SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tpj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 5tpj DENOVO NTF2
(synthetic
construct) 		4 / 6 PHE A  89
LEU A  17
VAL A  62
VAL A  76
 None
 1.16A 1dz4A-5tpjA:
undetectable		 1dz4A-5tpjA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 5tpj DENOVO NTF2
(synthetic
construct) 		4 / 6 PHE A  89
LEU A  17
VAL A  62
VAL A  76
 None
 1.16A 1dz4B-5tpjA:
undetectable		 1dz4B-5tpjA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 5tpj DENOVO NTF2
(synthetic
construct) 		4 / 5 PHE A  89
LEU A  17
VAL A  62
VAL A  76
 None
 1.14A 1t88B-5tpjA:
undetectable		 1t88B-5tpjA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5tpj DENOVO NTF2
(synthetic
construct) 		4 / 5 PHE A  89
LEU A  17
VAL A  62
VAL A  76
 None
 1.14A 2m56A-5tpjA:
undetectable		 2m56A-5tpjA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5tpj DENOVO NTF2
(synthetic
construct) 		4 / 6 PHE A  89
LEU A  17
VAL A  62
VAL A  76
 None
 1.11A 3fwgA-5tpjA:
undetectable		 3fwgA-5tpjA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 5tpj DENOVO NTF2
(synthetic
construct) 		4 / 6 PHE A  89
LEU A  17
VAL A  62
VAL A  76
 None
 1.11A 3wrhE-5tpjA:
undetectable		 3wrhE-5tpjA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 5tpj DENOVO NTF2
(synthetic
construct) 		4 / 6 PHE A  89
LEU A  17
VAL A  62
VAL A  76
 None
 1.13A 3wrjE-5tpjA:
undetectable		 3wrjE-5tpjA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5tpj DENOVO NTF2
(synthetic
construct) 		4 / 6 PHE A  89
LEU A  17
VAL A  62
VAL A  76
 None
 1.08A 4ek1A-5tpjA:
undetectable		 4ek1A-5tpjA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5tpj DENOVO NTF2
(synthetic
construct) 		4 / 6 PHE A  89
LEU A  17
VAL A  62
VAL A  76
 None
 1.12A 4g3rA-5tpjA:
undetectable		 4g3rA-5tpjA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 5tpj DENOVO NTF2
(synthetic
construct) 		4 / 6 PHE A  89
LEU A  17
VAL A  62
VAL A  76
 None
 1.13A 4kkyX-5tpjA:
undetectable		 4kkyX-5tpjA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5tpj DENOVO NTF2
(synthetic
construct) 		4 / 5 PHE A  89
LEU A  17
VAL A  62
VAL A  76
 None
 1.12A 4l49A-5tpjA:
undetectable		 4l49A-5tpjA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5tpj DENOVO NTF2
(synthetic
construct) 		4 / 6 PHE A  89
LEU A  17
VAL A  62
VAL A  76
 None
 1.08A 4l4cA-5tpjA:
undetectable		 4l4cA-5tpjA:
14.29