SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tpu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 5tpu PUTATIVE
UNCHARACTERIZED
PROTEIN
(Campylobacter
jejuni) 		5 / 12 ILE A  39
MET A  99
LEU A  60
ILE A  91
PHE A 102
 None
 1.29A 1y0xX-5tpuA:
undetectable		 1y0xX-5tpuA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 5tpu PUTATIVE
UNCHARACTERIZED
PROTEIN
(Campylobacter
jejuni) 		4 / 8 ILE A  61
ILE A  33
LYS A  93
GLY A  92
 None
 0.94A 4hdlA-5tpuA:
undetectable		 4hdlA-5tpuA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA505_0
(RNA POLYMERASE
3D-POL)		 5tpu PUTATIVE
UNCHARACTERIZED
PROTEIN
(Campylobacter
jejuni) 		3 / 3 CYH A  81
ASN A 101
LYS A  79
 None
 1.50A 4k50A-5tpuA:
undetectable		 4k50A-5tpuA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 5tpu PUTATIVE
UNCHARACTERIZED
PROTEIN
(Campylobacter
jejuni) 		5 / 12 LEU A  89
GLY A  65
ASN A  83
MET A  99
LEU A 108
 None
 1.32A 5emlA-5tpuA:
undetectable		 5emlA-5tpuA:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5tpu PUTATIVE
UNCHARACTERIZED
PROTEIN
(Campylobacter
jejuni) 		4 / 8 LEU A  89
ILE A  69
LEU A  60
MET A  62
 None
 0.94A 5g48A-5tpuA:
undetectable		 5g48A-5tpuA:
18.80