SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tpw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 5 GLY B 295
LEU B 299
THR B 300
VAL B  99
 None
 1.08A 1ekjF-5tpwB:
3.1
1ekjG-5tpwB:
3.1		 1ekjF-5tpwB:
18.46
1ekjG-5tpwB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 8 SER B 118
GLN B 111
PHE B 115
ASP B 114
 None
 1.34A 1p6kA-5tpwB:
undetectable		 1p6kA-5tpwB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 8 SER B 118
GLN B 111
PHE B 115
ASP B 114
 None
 1.26A 1p6kB-5tpwB:
undetectable		 1p6kB-5tpwB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		6 / 12 ILE B 116
THR B 120
ALA B 316
GLY B  97
LEU B  39
LEU B  89
 None
 1.33A 1rjdB-5tpwB:
undetectable		 1rjdB-5tpwB:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		6 / 12 ILE B 116
THR B 120
ALA B 316
GLY B  97
LEU B  39
LEU B  89
 None
 1.32A 1rjdC-5tpwB:
3.7		 1rjdC-5tpwB:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 8 SER B 118
GLN B 111
PHE B 115
ASP B 114
 None
 1.33A 1rs6B-5tpwB:
undetectable		 1rs6B-5tpwB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 8 SER B 118
GLN B 111
PHE B 115
ASP B 114
 None
 1.24A 1rs7B-5tpwB:
undetectable		 1rs7B-5tpwB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		5 / 10 GLY B 297
ALA B 302
ILE B 298
SER B 304
ALA B 303
 None
 1.18A 1utdT-5tpwB:
undetectable
1utdU-5tpwB:
undetectable		 1utdT-5tpwB:
13.62
1utdU-5tpwB:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 8 SER B 118
GLN B 111
PHE B 115
ASP B 114
 None
 1.30A 1zzuA-5tpwB:
undetectable		 1zzuA-5tpwB:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 8 SER B 118
GLN B 111
PHE B 115
ASP B 114
 None
 1.28A 1zzuB-5tpwB:
undetectable		 1zzuB-5tpwB:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		5 / 12 LEU B  40
GLY B 129
SER B  43
ALA B 131
ALA B 110
 None
 1.13A 2br4A-5tpwB:
4.5		 2br4A-5tpwB:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_1
(CATECHOL
O-METHYLTRANSFERASE)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 6 SER B  43
TYR B 286
SER B 259
GLN B 154
 None
 1.22A 2cl5B-5tpwB:
undetectable		 2cl5B-5tpwB:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 8 ILE B 127
PHE B 147
THR B 300
LEU B 299
 None
 0.82A 2eijN-5tpwB:
undetectable
2eijW-5tpwB:
undetectable		 2eijN-5tpwB:
20.58
2eijW-5tpwB:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 8 ILE B 127
PHE B 147
THR B 300
LEU B 299
 None
 0.84A 2eikN-5tpwB:
undetectable
2eikW-5tpwB:
undetectable		 2eikN-5tpwB:
20.58
2eikW-5tpwB:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 8 ILE B 127
PHE B 147
THR B 300
LEU B 299
 None
 0.82A 2eilN-5tpwB:
undetectable
2eilW-5tpwB:
undetectable		 2eilN-5tpwB:
20.58
2eilW-5tpwB:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 6 SER B  43
TYR B 286
SER B 259
GLN B 154
 None
 1.21A 2zvjA-5tpwB:
undetectable		 2zvjA-5tpwB:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 8 ILE B 127
PHE B 147
THR B 300
LEU B 299
 None
 0.86A 3ablN-5tpwB:
undetectable
3ablW-5tpwB:
undetectable		 3ablN-5tpwB:
20.58
3ablW-5tpwB:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 8 ILE B 127
PHE B 147
THR B 300
LEU B 299
 None
 0.81A 3ag3N-5tpwB:
undetectable
3ag3W-5tpwB:
undetectable		 3ag3N-5tpwB:
20.58
3ag3W-5tpwB:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 8 ILE B 127
PHE B 147
THR B 300
LEU B 299
 None
 0.86A 3asnN-5tpwB:
undetectable
3asnW-5tpwB:
undetectable		 3asnN-5tpwB:
20.58
3asnW-5tpwB:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		5 / 12 GLY B 297
GLY B 295
PHE B 145
ALA B 302
THR B 300
 None
 1.13A 3dh0B-5tpwB:
undetectable		 3dh0B-5tpwB:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 8 SER B 118
GLN B 111
PHE B 115
ASP B 114
 None
 1.31A 3n62A-5tpwB:
undetectable		 3n62A-5tpwB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 8 SER B 118
GLN B 111
PHE B 115
ASP B 114
 None
 1.23A 3n62B-5tpwB:
undetectable		 3n62B-5tpwB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 8 SER B 118
GLN B 111
PHE B 115
ASP B 114
 None
 1.33A 3n66B-5tpwB:
undetectable		 3n66B-5tpwB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A2000_1
(P38A)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		5 / 12 ASP B 294
ILE B 127
VAL B 362
ILE B 364
ALA B 290
 None
 1.12A 3ohtA-5tpwB:
undetectable
3ohtB-5tpwB:
undetectable		 3ohtA-5tpwB:
20.57
3ohtB-5tpwB:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 7 SER B 171
ILE B 222
THR B 174
THR B 175
 None
 0.92A 3tneB-5tpwB:
undetectable		 3tneB-5tpwB:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 7 ILE B 134
PHE B 350
HIS B 128
VAL B  38
 None
None
ZN  B 401 (-3.2A)
None
 1.11A 4a97A-5tpwB:
undetectable		 4a97A-5tpwB:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUB_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		3 / 3 TYR B 281
ARG B 291
HIS B 128
 None
None
ZN  B 401 (-3.2A)
 1.02A 4fubA-5tpwB:
undetectable		 4fubA-5tpwB:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2G_A_ADNA603_1
(5'-NUCLEOTIDASE)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		5 / 9 GLY B 126
PHE B 144
GLY B 129
PHE B 100
ASP B 102
 None
 1.21A 4h2gA-5tpwB:
undetectable		 4h2gA-5tpwB:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 7 SER B 118
GLN B 111
PHE B 115
ASP B 114
 None
 1.38A 4kcnB-5tpwB:
undetectable		 4kcnB-5tpwB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 7 ILE B 127
PHE B 147
THR B 300
LEU B 299
 None
 0.80A 5b1bN-5tpwB:
undetectable
5b1bW-5tpwB:
undetectable		 5b1bN-5tpwB:
20.58
5b1bW-5tpwB:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 7 ILE B 127
PHE B 147
THR B 300
LEU B 299
 None
 0.83A 5b3sN-5tpwB:
undetectable
5b3sW-5tpwB:
undetectable		 5b3sN-5tpwB:
20.58
5b3sW-5tpwB:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		5 / 10 GLY B 297
ALA B 302
ILE B 298
SER B 304
ALA B 303
 None
 1.19A 5eeuO-5tpwB:
undetectable
5eeuP-5tpwB:
undetectable		 5eeuO-5tpwB:
13.62
5eeuP-5tpwB:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		5 / 10 GLY B 297
ALA B 302
ILE B 298
SER B 304
ALA B 303
 None
 1.19A 5eevO-5tpwB:
undetectable
5eevP-5tpwB:
undetectable		 5eevO-5tpwB:
13.62
5eevP-5tpwB:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		5 / 10 GLY B 297
ALA B 302
ILE B 298
SER B 304
ALA B 303
 None
 1.19A 5eewO-5tpwB:
undetectable
5eewP-5tpwB:
undetectable		 5eewO-5tpwB:
13.62
5eewP-5tpwB:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		5 / 10 GLY B 297
ALA B 302
ILE B 298
SER B 304
ALA B 303
 None
 1.19A 5eexO-5tpwB:
undetectable
5eexP-5tpwB:
undetectable		 5eexO-5tpwB:
13.62
5eexP-5tpwB:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		5 / 10 GLY B 297
ALA B 302
ILE B 298
SER B 304
ALA B 303
 None
 1.19A 5eeyO-5tpwB:
undetectable
5eeyP-5tpwB:
undetectable		 5eeyO-5tpwB:
13.62
5eeyP-5tpwB:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		5 / 10 GLY B 297
ALA B 302
ILE B 298
SER B 304
ALA B 303
 None
 1.19A 5eezO-5tpwB:
undetectable
5eezP-5tpwB:
undetectable		 5eezO-5tpwB:
13.62
5eezP-5tpwB:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		5 / 10 GLY B 297
ALA B 302
ILE B 298
SER B 304
ALA B 303
 None
 1.19A 5ef0O-5tpwB:
undetectable
5ef0P-5tpwB:
undetectable		 5ef0O-5tpwB:
13.62
5ef0P-5tpwB:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		5 / 10 GLY B 297
ALA B 302
ILE B 298
SER B 304
ALA B 303
 None
 1.19A 5ef1O-5tpwB:
undetectable
5ef1P-5tpwB:
undetectable		 5ef1O-5tpwB:
13.62
5ef1P-5tpwB:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		5 / 10 GLY B 297
ALA B 302
ILE B 298
SER B 304
ALA B 303
 None
 1.19A 5ef2O-5tpwB:
undetectable
5ef2P-5tpwB:
undetectable		 5ef2O-5tpwB:
13.62
5ef2P-5tpwB:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		5 / 10 GLY B 297
ALA B 302
ILE B 298
SER B 304
ALA B 303
 None
 1.20A 5ef3O-5tpwB:
undetectable
5ef3P-5tpwB:
undetectable		 5ef3O-5tpwB:
13.62
5ef3P-5tpwB:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 7 ILE B 127
PHE B 147
THR B 300
LEU B 299
 None
 0.86A 5iy5N-5tpwB:
undetectable
5iy5W-5tpwB:
undetectable		 5iy5N-5tpwB:
20.58
5iy5W-5tpwB:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 8 VAL B  69
GLY B 297
LEU B 299
THR B 301
 None
 0.98A 5sxqB-5tpwB:
undetectable		 5sxqB-5tpwB:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 8 VAL B  69
GLY B 297
LEU B 299
THR B 301
 None
 0.96A 5syjA-5tpwB:
undetectable		 5syjA-5tpwB:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 8 ILE B 127
PHE B 147
THR B 300
LEU B 299
 None
 0.85A 5xdxN-5tpwB:
undetectable
5xdxW-5tpwB:
undetectable		 5xdxN-5tpwB:
20.58
5xdxW-5tpwB:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6L_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		5 / 9 ILE B 127
ALA B 290
ASP B 294
ILE B  36
PRO B 123
 None
 1.41A 5z6lA-5tpwB:
2.7		 5z6lA-5tpwB:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 8 ILE B 127
PHE B 147
THR B 300
LEU B 299
 None
 0.85A 5zcoA-5tpwB:
undetectable
5zcoJ-5tpwB:
undetectable		 5zcoA-5tpwB:
20.58
5zcoJ-5tpwB:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tpw GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2A
(Rattus
norvegicus) 		4 / 8 ILE B 127
PHE B 147
THR B 300
LEU B 299
 None
 0.83A 5zcqN-5tpwB:
undetectable
5zcqW-5tpwB:
undetectable		 5zcqN-5tpwB:
20.58
5zcqW-5tpwB:
11.44