SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tqb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQG_B_IBPB1701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	5tqb	60S RIBOSOMAL PROTEIN L4-LIKE PROTEIN (Chaetomium thermophilum)	5 / 11	VAL A 163 VAL A 153 SER A 155 ALA A 12 LEU A 172	None	1.06A	1eqgB-5tqbA: undetectable	1eqgB-5tqbA: 18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZBZ_A_VDXA501_1 (CYTOCHROME P450-SU1)	5tqb	60S RIBOSOMAL PROTEIN L4-LIKE PROTEIN (Chaetomium thermophilum)	5 / 11	THR A 145 VAL A 182 VAL A 256 ILE A 211 ALA A 175	None None EDO A 301 ( 4.7A) None None	1.21A	2zbzA-5tqbA: undetectable	2zbzA-5tqbA: 23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NUV_A_ASDA126_1 (STEROID DELTA-ISOMERASE)	5tqb	60S RIBOSOMAL PROTEIN L4-LIKE PROTEIN (Chaetomium thermophilum)	5 / 12	PHE A 27 SER A 130 LEU A 136 PHE A 254 VAL A 146	None EDO A 301 (-4.2A) EDO A 301 (-4.1A) EDO A 301 (-4.1A) None	1.40A	3nuvA-5tqbA: undetectable	3nuvA-5tqbA: 19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DH0_A_017A101_0 (PROTEASE)	5tqb	60S RIBOSOMAL PROTEIN L4-LIKE PROTEIN (Chaetomium thermophilum)	5 / 12	GLY A 177 ALA A 178 VAL A 232 ILE A 211 VAL A 182	None	0.88A	6dh0A-5tqbA: undetectable	6dh0A-5tqbA: 13.55

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EQG_B_IBPB1701_1","PROSTAGLANDIN H2 SYNTHASE-1","5tqb","60S RIBOSOMAL PROTEIN L4-LIKE PROTEIN","Chaetomium thermophilum",5,"VAL A 163;VAL A 153;SER A 155;ALA A  12;LEU A 172","None","1.06A","1eqgB-5tqbA:undetectable","1eqgB-5tqbA:18.21"],["2ZBZ_A_VDXA501_1","CYTOCHROME P450-SU1","5tqb","60S RIBOSOMAL PROTEIN L4-LIKE PROTEIN","Chaetomium thermophilum",5,"THR A 145;VAL A 182;VAL A 256;ILE A 211;ALA A 175","None;None;EDO A 301 ( 4.7A);None;None","1.21A","2zbzA-5tqbA:undetectable","2zbzA-5tqbA:23.44"],["3NUV_A_ASDA126_1","STEROID DELTA-ISOMERASE","5tqb","60S RIBOSOMAL PROTEIN L4-LIKE PROTEIN","Chaetomium thermophilum",5,"PHE A  27;SER A 130;LEU A 136;PHE A 254;VAL A 146","None;EDO A 301 (-4.2A);EDO A 301 (-4.1A);EDO A 301 (-4.1A);None","1.40A","3nuvA-5tqbA:undetectable","3nuvA-5tqbA:19.17"],["6DH0_A_017A101_0","PROTEASE","5tqb","60S RIBOSOMAL PROTEIN L4-LIKE PROTEIN","Chaetomium thermophilum",5,"GLY A 177;ALA A 178;VAL A 232;ILE A 211;VAL A 182","None","0.88A","6dh0A-5tqbA:undetectable","6dh0A-5tqbA:13.55"]]