SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tqj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NVK_J_SAMJ228_0 (FIBRILLARIN-LIKE RRNA/TRNA 2'-O-METHYLTRANSFERA SE NOP5/NOP56 RELATED PROTEIN)	5tqj	RESPONSE REGULATOR RECEIVER PROTEIN (Paraburkholderia phymatum)	5 / 12	GLY A 18 ALA A 15 ALA A 32 ASP A 12 VAL A 10	EDO A 204 ( 4.4A) EDO A 204 (-3.5A) None None None	1.25A	3nvkF-5tqjA: undetectable 3nvkJ-5tqjA: 4.2	3nvkF-5tqjA: 18.35 3nvkJ-5tqjA: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NNW_D_GCSD302_1 (25 KDA PROTEIN ELICITOR)	5tqj	RESPONSE REGULATOR RECEIVER PROTEIN (Paraburkholderia phymatum)	4 / 7	ASP A 12 GLY A 18 ASP A 59 ASP A 14	None EDO A 204 ( 4.4A) None None	0.93A	5nnwD-5tqjA: undetectable	5nnwD-5tqjA: 19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NO9_D_95ZD302_1 (25 KDA PROTEIN ELICITOR)	5tqj	RESPONSE REGULATOR RECEIVER PROTEIN (Paraburkholderia phymatum)	4 / 7	ASP A 12 GLY A 18 ASP A 59 ASP A 14	None EDO A 204 ( 4.4A) None None	0.92A	5no9D-5tqjA: undetectable	5no9D-5tqjA: 19.85

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3NVK_J_SAMJ228_0","FIBRILLARIN-LIKE RRNA\/TRNA 2'-O-METHYLTRANSFERASE;NOP5\/NOP56 RELATED PROTEIN","5tqj","RESPONSE REGULATOR RECEIVER PROTEIN","Paraburkholderia phymatum",5,"GLY A  18;ALA A  15;ALA A  32;ASP A  12;VAL A  10","EDO A 204 ( 4.4A);EDO A 204 (-3.5A);None;None;None","1.25A","3nvkF-5tqjA:undetectable;3nvkJ-5tqjA:4.2","3nvkF-5tqjA:18.35;3nvkJ-5tqjA:25.00"],["5NNW_D_GCSD302_1","25 KDA PROTEIN ELICITOR","5tqj","RESPONSE REGULATOR RECEIVER PROTEIN","Paraburkholderia phymatum",4,"ASP A  12;GLY A  18;ASP A  59;ASP A  14","None;EDO A 204 ( 4.4A);None;None","0.93A","5nnwD-5tqjA:undetectable","5nnwD-5tqjA:19.85"],["5NO9_D_95ZD302_1","25 KDA PROTEIN ELICITOR","5tqj","RESPONSE REGULATOR RECEIVER PROTEIN","Paraburkholderia phymatum",4,"ASP A  12;GLY A  18;ASP A  59;ASP A  14","None;EDO A 204 ( 4.4A);None;None","0.92A","5no9D-5tqjA:undetectable","5no9D-5tqjA:19.85"]]