SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tr0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		5 / 12 LEU A 742
PHE A 270
ILE A 297
LEU A 299
PRO A 300
 None
 1.13A 1re7B-5tr0A:
undetectable		 1re7B-5tr0A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.01A 1v54A-5tr0A:
3.0
1v54C-5tr0A:
undetectable		 1v54A-5tr0A:
21.71
1v54C-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.01A 1v54N-5tr0A:
0.8
1v54P-5tr0A:
undetectable		 1v54N-5tr0A:
21.71
1v54P-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.01A 1v55A-5tr0A:
3.1
1v55C-5tr0A:
undetectable		 1v55A-5tr0A:
21.71
1v55C-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YI4_A_ADNA306_1
(PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		5 / 10 LEU A 675
ILE A 683
LEU A 680
LEU A 528
ILE A 682
 None
 0.98A 1yi4A-5tr0A:
undetectable		 1yi4A-5tr0A:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 THR A  62
PHE A  35
GLU A  65
GLY A  66
 None
 1.08A 1ykiC-5tr0A:
undetectable
1ykiD-5tr0A:
undetectable		 1ykiC-5tr0A:
14.68
1ykiD-5tr0A:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		3 / 3 THR A 773
PRO A 523
TYR A 628
 None
 0.91A 2dxrA-5tr0A:
undetectable		 2dxrA-5tr0A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.02A 2dyrA-5tr0A:
2.8
2dyrC-5tr0A:
undetectable		 2dyrA-5tr0A:
21.71
2dyrC-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.02A 2dyrN-5tr0A:
undetectable
2dyrP-5tr0A:
undetectable		 2dyrN-5tr0A:
21.71
2dyrP-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.01A 2eijA-5tr0A:
3.3
2eijC-5tr0A:
undetectable		 2eijA-5tr0A:
21.71
2eijC-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.00A 2eijN-5tr0A:
2.2
2eijP-5tr0A:
undetectable		 2eijN-5tr0A:
21.71
2eijP-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 0.99A 2eikA-5tr0A:
2.4
2eikC-5tr0A:
undetectable		 2eikA-5tr0A:
21.71
2eikC-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 0.97A 2eikN-5tr0A:
undetectable
2eikP-5tr0A:
undetectable		 2eikN-5tr0A:
21.71
2eikP-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.00A 2eilA-5tr0A:
undetectable
2eilC-5tr0A:
undetectable		 2eilA-5tr0A:
21.71
2eilC-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 0.98A 2eilN-5tr0A:
3.0
2eilP-5tr0A:
undetectable		 2eilN-5tr0A:
21.71
2eilP-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_1
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		3 / 3 ARG A 831
ASP A 613
ASP A 607
 None
 0.89A 2ejtA-5tr0A:
undetectable		 2ejtA-5tr0A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 6 VAL A 564
SER A 567
LEU A 546
HIS A 499
 None
None
None
FE2  A 901 (-3.6A)
 1.25A 2f8dA-5tr0A:
undetectable		 2f8dA-5tr0A:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 SER A 451
SER A 464
VAL A 466
LEU A 362
 None
 1.06A 2hdnE-5tr0A:
undetectable
2hdnF-5tr0A:
undetectable
2hdnH-5tr0A:
undetectable		 2hdnE-5tr0A:
4.81
2hdnF-5tr0A:
18.29
2hdnH-5tr0A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 SER A 464
VAL A 466
LEU A 362
SER A 451
 None
 0.99A 2hdnF-5tr0A:
undetectable
2hdnG-5tr0A:
undetectable
2hdnH-5tr0A:
undetectable		 2hdnF-5tr0A:
18.29
2hdnG-5tr0A:
4.81
2hdnH-5tr0A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TYR A 698
GLN A 334
TYR A 293
ILE A 704
 None
 1.05A 2ph9A-5tr0A:
undetectable
2ph9B-5tr0A:
undetectable		 2ph9A-5tr0A:
15.44
2ph9B-5tr0A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		3 / 3 LEU A  71
PRO A  72
ARG A 124
 None
 0.63A 2qd4B-5tr0A:
undetectable		 2qd4B-5tr0A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		3 / 3 PRO A 816
ASN A 800
ARG A 809
 None
 0.95A 2qeuB-5tr0A:
undetectable		 2qeuB-5tr0A:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 ASN A 355
SER A 491
VAL A 358
PHE A 413
 None
 1.27A 2wekB-5tr0A:
undetectable		 2wekB-5tr0A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.02A 2y69C-5tr0A:
undetectable
2y69N-5tr0A:
2.7
2y69P-5tr0A:
undetectable		 2y69C-5tr0A:
14.81
2y69N-5tr0A:
21.71
2y69P-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.01A 3abkA-5tr0A:
3.4
3abkC-5tr0A:
undetectable		 3abkA-5tr0A:
21.71
3abkC-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 6 ILE A 434
ILE A 487
LEU A 362
PHE A 405
 None
 1.13A 3adsA-5tr0A:
undetectable		 3adsA-5tr0A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 0.97A 3ag2A-5tr0A:
2.1
3ag2C-5tr0A:
undetectable		 3ag2A-5tr0A:
21.71
3ag2C-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.02A 3ag2N-5tr0A:
2.4
3ag2P-5tr0A:
undetectable		 3ag2N-5tr0A:
21.71
3ag2P-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.00A 3ag3A-5tr0A:
2.8
3ag3C-5tr0A:
undetectable		 3ag3A-5tr0A:
21.71
3ag3C-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.01A 3ag4A-5tr0A:
undetectable
3ag4C-5tr0A:
undetectable		 3ag4A-5tr0A:
21.71
3ag4C-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.02A 3asnC-5tr0A:
undetectable
3asnN-5tr0A:
undetectable
3asnP-5tr0A:
undetectable		 3asnC-5tr0A:
14.81
3asnN-5tr0A:
21.71
3asnP-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 0.99A 3asoA-5tr0A:
undetectable
3asoC-5tr0A:
undetectable
3asoP-5tr0A:
undetectable		 3asoA-5tr0A:
21.71
3asoC-5tr0A:
14.81
3asoP-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.00A 3asoC-5tr0A:
undetectable
3asoN-5tr0A:
3.3
3asoP-5tr0A:
undetectable		 3asoC-5tr0A:
14.81
3asoN-5tr0A:
21.71
3asoP-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		5 / 12 ALA A 652
LEU A 527
LEU A 528
ILE A 682
ILE A 621
 None
 1.00A 3gcsA-5tr0A:
undetectable		 3gcsA-5tr0A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_D_HCZD800_1
(GLUTAMATE RECEPTOR 2)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		5 / 9 ILE A 524
PRO A 523
SER A 643
SER A 152
LEU A 675
 None
 1.47A 3ijxB-5tr0A:
undetectable
3ijxD-5tr0A:
undetectable		 3ijxB-5tr0A:
15.52
3ijxD-5tr0A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 SER A 498
ASN A 355
GLN A 697
ASN A 502
 None
 1.24A 3n62A-5tr0A:
undetectable		 3n62A-5tr0A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 SER A 498
ASN A 355
GLN A 697
ASN A 502
 None
 1.26A 3n66B-5tr0A:
undetectable		 3n66B-5tr0A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 6 ALA A 686
ILE A 837
VAL A 511
ASN A 535
 None
 1.00A 3nneG-5tr0A:
undetectable		 3nneG-5tr0A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5V_C_ACTC510_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 5 ARG A 219
THR A 220
ASP A 187
GLU A 232
 None
 1.17A 3v5vC-5tr0A:
undetectable
3v5vD-5tr0A:
undetectable		 3v5vC-5tr0A:
19.86
3v5vD-5tr0A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 GLN A 495
HIS A 499
HIS A 690
HIS A 504
 None
FE2  A 901 (-3.6A)
FE2  A 901 (-3.6A)
FE2  A 901 (-3.5A)
 0.84A 3w6hA-5tr0A:
undetectable		 3w6hA-5tr0A:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.02A 3wg7A-5tr0A:
undetectable
3wg7C-5tr0A:
undetectable
3wg7P-5tr0A:
1.2		 3wg7A-5tr0A:
21.71
3wg7C-5tr0A:
14.81
3wg7P-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.00A 3x2qA-5tr0A:
3.3
3x2qC-5tr0A:
undetectable
3x2qP-5tr0A:
undetectable		 3x2qA-5tr0A:
21.71
3x2qC-5tr0A:
14.81
3x2qP-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.02A 3x2qC-5tr0A:
undetectable
3x2qN-5tr0A:
undetectable
3x2qP-5tr0A:
undetectable		 3x2qC-5tr0A:
14.81
3x2qN-5tr0A:
21.71
3x2qP-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		3 / 3 TRP A 574
TRP A 665
THR A 577
 None
 1.50A 4bboB-5tr0A:
0.9		 4bboB-5tr0A:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_F_SASF805_1
(SEPIAPTERIN
REDUCTASE)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		5 / 12 SER A 749
LEU A 748
TYR A 317
ASP A 291
ASP A 288
 None
 1.37A 4j7xF-5tr0A:
undetectable		 4j7xF-5tr0A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 VAL A 629
TYR A 628
LEU A 518
LEU A 645
 None
 0.87A 4jtrA-5tr0A:
undetectable		 4jtrA-5tr0A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 SER A 498
ASN A 355
GLN A 697
ASN A 502
 None
 1.25A 4kcnB-5tr0A:
undetectable		 4kcnB-5tr0A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 GLN A 495
HIS A 499
HIS A 690
HIS A 504
 None
FE2  A 901 (-3.6A)
FE2  A 901 (-3.6A)
FE2  A 901 (-3.5A)
 0.92A 4n16A-5tr0A:
undetectable		 4n16A-5tr0A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 ILE A 553
GLN A 495
HIS A 499
HIS A 690
 None
None
FE2  A 901 (-3.6A)
FE2  A 901 (-3.6A)
 0.87A 4n16A-5tr0A:
undetectable		 4n16A-5tr0A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		5 / 12 LEU A 299
LEU A 745
ILE A 746
LEU A 742
ILE A 265
 None
 0.94A 4odrA-5tr0A:
undetectable
4odrB-5tr0A:
undetectable		 4odrA-5tr0A:
9.47
4odrB-5tr0A:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		5 / 11 LEU A 299
LEU A 745
ILE A 746
LEU A 742
ILE A 265
 None
 1.01A 4odrA-5tr0A:
undetectable
4odrB-5tr0A:
undetectable		 4odrA-5tr0A:
9.47
4odrB-5tr0A:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 5 ARG A 767
THR A 773
ASP A 775
TYR A 632
 None
 1.49A 4oltB-5tr0A:
0.6		 4oltB-5tr0A:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 PHE A 283
TYR A 734
GLY A 702
ILE A 751
 None
 0.97A 4qoiA-5tr0A:
undetectable
4qoiB-5tr0A:
undetectable		 4qoiA-5tr0A:
16.52
4qoiB-5tr0A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		5 / 11 ASN A 539
HIS A 504
HIS A 499
HIS A 690
ALA A 754
 None
FE2  A 901 (-3.5A)
FE2  A 901 (-3.6A)
FE2  A 901 (-3.6A)
None
 1.49A 4ygfA-5tr0A:
undetectable		 4ygfA-5tr0A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		5 / 11 ASN A 539
HIS A 504
HIS A 499
HIS A 690
ALA A 754
 None
FE2  A 901 (-3.5A)
FE2  A 901 (-3.6A)
FE2  A 901 (-3.6A)
None
 1.43A 4ygfC-5tr0A:
undetectable		 4ygfC-5tr0A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 0.99A 5b1bN-5tr0A:
3.4
5b1bP-5tr0A:
undetectable		 5b1bN-5tr0A:
21.71
5b1bP-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.00A 5b3sA-5tr0A:
undetectable
5b3sC-5tr0A:
undetectable
5b3sP-5tr0A:
undetectable		 5b3sA-5tr0A:
21.71
5b3sC-5tr0A:
14.81
5b3sP-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.02A 5b3sN-5tr0A:
undetectable
5b3sP-5tr0A:
undetectable		 5b3sN-5tr0A:
21.71
5b3sP-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 6 TYR A 317
GLY A 258
SER A 261
LEU A 262
 None
 1.09A 5bphA-5tr0A:
undetectable		 5bphA-5tr0A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 4 TYR A 317
GLY A 258
SER A 261
LEU A 262
 None
 1.11A 5bphC-5tr0A:
undetectable		 5bphC-5tr0A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.03A 5iy5A-5tr0A:
undetectable
5iy5C-5tr0A:
undetectable		 5iy5A-5tr0A:
21.71
5iy5C-5tr0A:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.04A 5iy5C-5tr0A:
undetectable
5iy5N-5tr0A:
undetectable
5iy5P-5tr0A:
undetectable		 5iy5C-5tr0A:
14.79
5iy5N-5tr0A:
21.71
5iy5P-5tr0A:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 LEU A 546
LEU A 496
ILE A 704
THR A 709
 None
 1.04A 5ljbA-5tr0A:
undetectable		 5ljbA-5tr0A:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_B_RITB602_1
(CYTOCHROME P450 3A5)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		5 / 12 PHE A 785
ILE A 683
ALA A 686
ALA A 692
GLY A 832
 None
 1.08A 5veuB-5tr0A:
undetectable		 5veuB-5tr0A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 PHE A 413
ILE A 448
SER A 711
THR A 428
 None
 0.99A 5vkqA-5tr0A:
3.4
5vkqD-5tr0A:
3.4		 5vkqA-5tr0A:
18.88
5vkqD-5tr0A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 SER A 711
THR A 428
PHE A 413
ILE A 448
 None
 0.99A 5vkqA-5tr0A:
3.4
5vkqB-5tr0A:
3.4		 5vkqA-5tr0A:
18.88
5vkqB-5tr0A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 SER A 711
THR A 428
PHE A 413
ILE A 448
 None
 0.97A 5vkqB-5tr0A:
3.4
5vkqC-5tr0A:
3.3		 5vkqB-5tr0A:
18.88
5vkqC-5tr0A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 SER A 711
THR A 428
PHE A 413
ILE A 448
 None
 0.99A 5vkqC-5tr0A:
3.3
5vkqD-5tr0A:
3.4		 5vkqC-5tr0A:
18.88
5vkqD-5tr0A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 SER A 498
ASN A 355
GLN A 697
ASN A 502
 None
 1.27A 5vunA-5tr0A:
undetectable		 5vunA-5tr0A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 SER A 498
ASN A 355
GLN A 697
ASN A 502
 None
 1.27A 5vunB-5tr0A:
undetectable		 5vunB-5tr0A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 SER A 498
ASN A 355
GLN A 697
ASN A 502
 None
 1.25A 5vuoB-5tr0A:
undetectable		 5vuoB-5tr0A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.05A 5w97A-5tr0A:
2.3
5w97C-5tr0A:
undetectable
5w97c-5tr0A:
undetectable		 5w97A-5tr0A:
21.71
5w97C-5tr0A:
14.81
5w97c-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 0.99A 5wauA-5tr0A:
undetectable
5wauC-5tr0A:
undetectable
5wauc-5tr0A:
undetectable		 5wauA-5tr0A:
21.71
5wauC-5tr0A:
14.81
5wauc-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.03A 5x19A-5tr0A:
undetectable
5x19C-5tr0A:
undetectable
5x19P-5tr0A:
undetectable		 5x19A-5tr0A:
21.71
5x19C-5tr0A:
14.81
5x19P-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.01A 5xdqA-5tr0A:
undetectable
5xdqC-5tr0A:
undetectable
5xdqP-5tr0A:
undetectable		 5xdqA-5tr0A:
21.71
5xdqC-5tr0A:
14.81
5xdqP-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.02A 5xdxC-5tr0A:
undetectable
5xdxN-5tr0A:
3.5
5xdxP-5tr0A:
undetectable		 5xdxC-5tr0A:
14.78
5xdxN-5tr0A:
21.71
5xdxP-5tr0A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.00A 5z84A-5tr0A:
undetectable
5z84C-5tr0A:
undetectable
5z84P-5tr0A:
undetectable		 5z84A-5tr0A:
21.71
5z84C-5tr0A:
14.81
5z84P-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 0.99A 5z85A-5tr0A:
3.5
5z85C-5tr0A:
undetectable
5z85P-5tr0A:
undetectable		 5z85A-5tr0A:
21.71
5z85C-5tr0A:
14.81
5z85P-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 0.99A 5z86A-5tr0A:
undetectable
5z86C-5tr0A:
undetectable
5z86P-5tr0A:
undetectable		 5z86A-5tr0A:
21.71
5z86C-5tr0A:
14.81
5z86P-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.03A 5z86C-5tr0A:
undetectable
5z86N-5tr0A:
2.9
5z86P-5tr0A:
undetectable		 5z86C-5tr0A:
14.81
5z86N-5tr0A:
21.71
5z86P-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.00A 5zcoA-5tr0A:
3.3
5zcoC-5tr0A:
undetectable
5zcoP-5tr0A:
undetectable		 5zcoA-5tr0A:
21.71
5zcoC-5tr0A:
14.81
5zcoP-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.01A 5zcoC-5tr0A:
undetectable
5zcoN-5tr0A:
undetectable
5zcoP-5tr0A:
undetectable		 5zcoC-5tr0A:
14.81
5zcoN-5tr0A:
21.71
5zcoP-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.02A 5zcpA-5tr0A:
3.3
5zcpC-5tr0A:
undetectable
5zcpP-5tr0A:
undetectable		 5zcpA-5tr0A:
21.71
5zcpC-5tr0A:
14.81
5zcpP-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.02A 5zcpC-5tr0A:
undetectable
5zcpN-5tr0A:
3.3
5zcpP-5tr0A:
undetectable		 5zcpC-5tr0A:
14.81
5zcpN-5tr0A:
21.71
5zcpP-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.01A 5zcqA-5tr0A:
3.2
5zcqC-5tr0A:
undetectable
5zcqP-5tr0A:
undetectable		 5zcqA-5tr0A:
21.71
5zcqC-5tr0A:
14.81
5zcqP-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.01A 5zcqN-5tr0A:
undetectable
5zcqP-5tr0A:
undetectable		 5zcqN-5tr0A:
21.71
5zcqP-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 SER A 498
ASN A 355
GLN A 697
ASN A 502
 None
 1.27A 6auuB-5tr0A:
undetectable		 6auuB-5tr0A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 6 PHE A 327
VAL A 266
LEU A 742
LEU A 745
 None
 1.03A 6e43A-5tr0A:
0.8		 6e43A-5tr0A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 6 PHE A 327
VAL A 266
LEU A 742
LEU A 745
 None
 1.02A 6e43C-5tr0A:
undetectable		 6e43C-5tr0A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 ASP A 490
GLY A 811
ASN A 706
VAL A 332
 None
 1.08A 6giqL-5tr0A:
undetectable
6giqP-5tr0A:
undetectable
6giqT-5tr0A:
undetectable		 6giqL-5tr0A:
21.47
6giqP-5tr0A:
13.37
6giqT-5tr0A:
5.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 ALA A 542
THR A 259
ILE A 753
ALA A 754
 None
 0.68A 6ma7A-5tr0A:
undetectable		 6ma7A-5tr0A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 8 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.00A 6nknC-5tr0A:
undetectable
6nknN-5tr0A:
undetectable
6nknP-5tr0A:
undetectable		 6nknC-5tr0A:
14.81
6nknN-5tr0A:
21.71
6nknP-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 0.99A 6nmfN-5tr0A:
undetectable
6nmfP-5tr0A:
undetectable		 6nmfN-5tr0A:
21.71
6nmfP-5tr0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1
(Glycine
max) 		4 / 7 TRP A 649
ASP A 659
TRP A 648
HIS A 517
 None
 1.01A 6nmpN-5tr0A:
undetectable
6nmpP-5tr0A:
undetectable		 6nmpN-5tr0A:
21.71
6nmpP-5tr0A:
14.81