SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tr7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		7 / 12 ALA A  65
SER A  66
LYS A  69
SER A 129
ASN A 131
LYS A 232
GLY A 234
 None
 0.59A 1ghmA-5tr7A:
21.6		 1ghmA-5tr7A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		7 / 12 ALA A  65
SER A  66
LYS A  69
SER A 129
ASN A 131
LYS A 232
GLY A 234
 None
 0.57A 1i2wA-5tr7A:
22.3		 1i2wA-5tr7A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		6 / 12 ALA A  65
SER A  66
LYS A  69
SER A 129
ASN A 131
GLY A 234
 None
 0.58A 1i2wB-5tr7A:
22.4		 1i2wB-5tr7A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		6 / 12 SER A  66
LYS A  69
SER A 129
ASN A 131
LYS A 232
GLY A 234
 None
 0.55A 1ymxA-5tr7A:
22.1		 1ymxA-5tr7A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		6 / 12 SER A  66
LYS A  69
SER A 129
ASN A 131
LYS A 232
GLY A 234
 None
 0.54A 1ymxB-5tr7A:
22.0		 1ymxB-5tr7A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_2
(HIV-1 PROTEASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		3 / 3 ARG A 217
VAL A 258
THR A 261
 None
 0.70A 3cyxA-5tr7A:
undetectable		 3cyxA-5tr7A:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_2
(RENIN)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		4 / 5 TYR A 182
ALA A 190
ALA A 256
MET A 259
 None
 0.85A 3d91A-5tr7A:
undetectable		 3d91A-5tr7A:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		5 / 9 ALA A  97
GLY A 130
ILE A 125
VAL A 116
ILE A  93
 None
 1.08A 3ekvB-5tr7A:
undetectable		 3ekvB-5tr7A:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_1
(REPRESSOR PROTEIN
MPHR(A))		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		4 / 7 ASN A 263
ARG A 267
ASN A 242
ALA A 239
 None
NO2  A 403 (-3.7A)
None
None
 1.33A 3frqB-5tr7A:
0.8		 3frqB-5tr7A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		5 / 12 LYS A  69
ASN A 131
LYS A 232
THR A 233
GLY A 234
 None
 0.55A 3huoA-5tr7A:
22.1		 3huoA-5tr7A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		5 / 12 HIS A  48
ASP A  46
GLY A 250
PHE A 279
ALA A 247
 None
 1.08A 3keeA-5tr7A:
undetectable		 3keeA-5tr7A:
17.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		6 / 12 ALA A  65
LYS A  69
THR A 233
GLY A 234
THR A 236
ARG A 267
 None
None
None
None
None
NO2  A 403 (-3.7A)
 1.28A 3mzeA-5tr7A:
41.3		 3mzeA-5tr7A:
58.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		8 / 12 ALA A  65
SER A  66
LYS A  69
ASN A 131
LEU A 172
THR A 233
GLY A 234
ARG A 267
 None
None
None
None
None
None
None
NO2  A 403 (-3.7A)
 0.76A 3mzeA-5tr7A:
41.3		 3mzeA-5tr7A:
58.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		6 / 12 ALA A  65
SER A  66
LYS A  69
LEU A 172
ARG A 217
THR A 233
 None
 1.30A 3mzeA-5tr7A:
41.3		 3mzeA-5tr7A:
58.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		3 / 3 SER A 105
SER A 106
HIS A 235
 None
 0.72A 3mzeA-5tr7A:
41.3		 3mzeA-5tr7A:
58.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		6 / 12 SER A  66
SER A 129
ARG A 267
LYS A 232
THR A 233
GLY A 234
 None
None
NO2  A 403 (-3.7A)
None
None
None
 0.85A 3ny4A-5tr7A:
21.7		 3ny4A-5tr7A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		5 / 12 LYS A  69
SER A 129
ASN A 131
LYS A 232
GLY A 234
 None
 0.62A 3q07A-5tr7A:
22.1		 3q07A-5tr7A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		5 / 12 LYS A  69
SER A 129
ASN A 131
LYS A 232
GLY A 234
 None
 0.56A 3q07B-5tr7A:
22.1		 3q07B-5tr7A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		3 / 3 HIS A 165
SER A  63
ASN A 168
 None
 0.89A 3s8pB-5tr7A:
undetectable		 3s8pB-5tr7A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		7 / 12 ALA A  65
SER A  66
SER A 129
ASN A 131
LYS A 232
THR A 233
GLY A 234
 None
 0.69A 3sh8A-5tr7A:
22.5		 3sh8A-5tr7A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		7 / 12 ALA A  65
SER A  66
LYS A  69
SER A 129
ASN A 131
LYS A 232
GLY A 234
 None
 0.74A 3sh8B-5tr7A:
22.1		 3sh8B-5tr7A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		6 / 12 ALA A  65
SER A  66
LYS A  69
SER A 129
GLY A 234
TYR A 241
 None
 1.00A 3sh8B-5tr7A:
22.1		 3sh8B-5tr7A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		5 / 12 HIS A  48
ASP A  46
GLY A 250
PHE A 279
ALA A 247
 None
 1.05A 3sudA-5tr7A:
undetectable		 3sudA-5tr7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		5 / 12 HIS A  48
ASP A  46
GLY A 250
PHE A 279
ALA A 247
 None
 1.10A 3sueB-5tr7A:
undetectable		 3sueB-5tr7A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		5 / 12 HIS A  48
ASP A  46
GLY A 250
PHE A 279
ALA A 247
 None
 1.06A 3sufA-5tr7A:
undetectable		 3sufA-5tr7A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		5 / 11 HIS A  48
ASP A  46
GLY A 250
PHE A 279
ALA A 247
 None
 1.15A 3sufC-5tr7A:
undetectable		 3sufC-5tr7A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		5 / 12 HIS A  48
ASP A  46
GLY A 250
PHE A 279
ALA A 247
 None
 1.05A 3sugA-5tr7A:
undetectable		 3sugA-5tr7A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		3 / 3 TYR A  47
MET A  71
LEU A 159
 None
 0.94A 3vw1D-5tr7A:
undetectable		 3vw1D-5tr7A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		3 / 3 ASP A 183
GLY A 160
TYR A 182
 None
 0.74A 3w9tC-5tr7A:
undetectable		 3w9tC-5tr7A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		3 / 3 ASP A 183
GLY A 160
TYR A 182
 None
 0.75A 3w9tG-5tr7A:
undetectable		 3w9tG-5tr7A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		5 / 10 ALA A  97
GLY A 130
ILE A 125
VAL A 116
ILE A  93
 None
 1.11A 4dqcA-5tr7A:
undetectable		 4dqcA-5tr7A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		4 / 7 LEU A 191
TYR A 202
ILE A 125
GLY A  77
 None
 0.88A 4eq4A-5tr7A:
undetectable		 4eq4A-5tr7A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		4 / 7 LEU A 191
TYR A 202
ILE A 125
GLY A  77
 None
 0.89A 4eqlA-5tr7A:
undetectable		 4eqlA-5tr7A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		4 / 7 LEU A 191
TYR A 202
ILE A 125
GLY A  77
 None
 0.89A 4eqlB-5tr7A:
undetectable		 4eqlB-5tr7A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		7 / 12 LYS A  69
SER A 129
ASN A 131
LEU A 172
LYS A 232
THR A 233
GLY A 234
 None
 0.80A 4euzA-5tr7A:
22.1		 4euzA-5tr7A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		5 / 10 SER A 129
ASN A 131
LYS A 232
THR A 233
GLY A 234
 None
 0.62A 4fh2A-5tr7A:
22.7		 4fh2A-5tr7A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		4 / 6 LEU A 191
TYR A 202
ILE A 125
GLY A  77
 None
 1.00A 4l39A-5tr7A:
undetectable		 4l39A-5tr7A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		4 / 7 LEU A 191
TYR A 202
ILE A 125
GLY A  77
 None
 0.96A 4l39B-5tr7A:
undetectable		 4l39B-5tr7A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		7 / 12 ALA A  65
SER A  66
SER A 129
ASN A 131
LYS A 232
THR A 233
GLY A 234
 None
 0.69A 4n9kA-5tr7A:
22.3		 4n9kA-5tr7A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		7 / 12 ALA A  65
SER A  66
SER A 129
ASN A 131
LYS A 232
THR A 233
GLY A 234
 None
 0.68A 4n9kB-5tr7A:
22.4		 4n9kB-5tr7A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_2
(ASPARTYL PROTEASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		5 / 10 ALA A  97
GLY A 130
ILE A 125
VAL A 116
ILE A  93
 None
 1.09A 4q1wB-5tr7A:
undetectable		 4q1wB-5tr7A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		3 / 3 MET A 137
GLN A  78
TYR A  74
 None
 1.01A 4udcA-5tr7A:
undetectable		 4udcA-5tr7A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		4 / 5 LEU A 191
TYR A 202
ASN A 122
ILE A  76
 None
 1.12A 4y03B-5tr7A:
undetectable		 4y03B-5tr7A:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		3 / 3 HIS A 165
SER A  63
ASN A 168
 None
 0.87A 5cprB-5tr7A:
undetectable		 5cprB-5tr7A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		6 / 12 ALA A  65
SER A  66
SER A 129
ASN A 131
LYS A 232
GLY A 234
 None
 0.75A 5ghyA-5tr7A:
22.1		 5ghyA-5tr7A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		6 / 12 ALA A  65
SER A  66
SER A 129
ASN A 131
LYS A 232
GLY A 234
 None
 0.71A 5ghyB-5tr7A:
22.1		 5ghyB-5tr7A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		7 / 11 ALA A  65
SER A  66
SER A 129
ASN A 131
LYS A 232
THR A 233
GLY A 234
 None
 0.69A 5ghzA-5tr7A:
22.2		 5ghzA-5tr7A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		7 / 10 ALA A  65
SER A  66
SER A 129
ASN A 131
LYS A 232
THR A 233
GLY A 234
 None
 0.69A 5ghzB-5tr7A:
22.1		 5ghzB-5tr7A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_C_MMZC503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		4 / 4 TYR A 199
ASN A 218
SER A 245
SER A 246
 None
 1.36A 5gsnC-5tr7A:
undetectable		 5gsnC-5tr7A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		5 / 12 GLY A 234
LEU A 275
GLY A 230
ASN A 218
ILE A 231
 None
 1.02A 5vopA-5tr7A:
undetectable		 5vopA-5tr7A:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		5 / 12 GLY A 234
LEU A 275
GLY A 230
ASN A 218
ILE A 231
 None
 1.10A 5vopB-5tr7A:
undetectable		 5vopB-5tr7A:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		6 / 12 SER A  66
SER A 129
ARG A 267
LYS A 232
GLY A 234
GLU A 264
 None
None
NO2  A 403 (-3.7A)
None
None
NO2  A 403 (-4.2A)
 0.83A 6b68D-5tr7A:
21.9		 6b68D-5tr7A:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		7 / 12 SER A  66
SER A 129
ARG A 267
LYS A 232
THR A 233
GLY A 234
GLU A 264
 None
None
NO2  A 403 (-3.7A)
None
None
None
NO2  A 403 (-4.2A)
 0.79A 6b69D-5tr7A:
21.9		 6b69D-5tr7A:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		6 / 12 SER A  66
SER A 129
ARG A 267
LYS A 232
THR A 233
GLY A 234
 None
None
NO2  A 403 (-3.7A)
None
None
None
 0.73A 6b6aB-5tr7A:
21.9		 6b6aB-5tr7A:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		7 / 12 SER A  66
SER A 129
ARG A 267
LYS A 232
THR A 233
GLY A 234
GLU A 264
 None
None
NO2  A 403 (-3.7A)
None
None
None
NO2  A 403 (-4.2A)
 0.79A 6b6aD-5tr7A:
21.9		 6b6aD-5tr7A:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		6 / 12 SER A  66
SER A 129
ARG A 267
LYS A 232
THR A 233
GLY A 234
 None
None
NO2  A 403 (-3.7A)
None
None
None
 0.70A 6b6cA-5tr7A:
22.1		 6b6cA-5tr7A:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 5tr7 D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Vibrio
cholerae) 		6 / 12 SER A  66
SER A 129
ARG A 267
LYS A 232
THR A 233
GLY A 234
 None
None
NO2  A 403 (-3.7A)
None
None
None
 0.79A 6b6eA-5tr7A:
22.0		 6b6eA-5tr7A:
13.71