SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tro'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 12 SER A 314
LYS A 317
SER A 368
ASN A 370
LYS A 513
GLY A 515
 None
 0.40A 1ghmA-5troA:
16.5		 1ghmA-5troA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 12 SER A 314
LYS A 317
SER A 368
ASN A 370
LYS A 513
GLY A 515
 None
 0.41A 1i2wA-5troA:
16.6		 1i2wA-5troA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		5 / 9 ILE A 181
GLY A 198
ILE A  68
ALA A  77
ARG A 169
 None
 1.26A 1mrgA-5troA:
undetectable		 1mrgA-5troA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 12 SER A 314
LYS A 317
SER A 368
ASN A 370
LYS A 513
GLY A 515
 None
 0.52A 1ymxA-5troA:
17.1		 1ymxA-5troA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 12 SER A 314
LYS A 317
SER A 368
ASN A 370
LYS A 513
GLY A 515
 None
 0.49A 1ymxB-5troA:
17.3		 1ymxB-5troA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		4 / 6 PRO A 431
ILE A 280
ASN A 303
LEU A 180
 None
 1.34A 2wekB-5troA:
undetectable		 2wekB-5troA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOB_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		5 / 12 MET A 373
GLN A 377
PHE A 330
ALA A 329
GLY A 381
 None
 1.50A 3aobC-5troA:
undetectable		 3aobC-5troA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		5 / 12 LYS A 317
SER A 368
ASN A 370
LYS A 513
GLY A 515
 None
 0.40A 3hlwA-5troA:
17.1		 3hlwA-5troA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		5 / 12 SER A 368
ASN A 370
LYS A 513
THR A 514
GLY A 515
 None
 0.30A 3hlwB-5troA:
17.3		 3hlwB-5troA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		5 / 12 LYS A 317
ASN A 370
LYS A 513
THR A 514
GLY A 515
 None
 0.35A 3huoA-5troA:
17.3		 3huoA-5troA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 12 SER A 314
SER A 368
LYS A 513
THR A 514
GLY A 515
THR A 516
 None
 0.49A 3ny4A-5troA:
17.1		 3ny4A-5troA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		5 / 12 LYS A 317
SER A 368
ASN A 370
LYS A 513
GLY A 515
 None
 0.36A 3q07A-5troA:
17.2		 3q07A-5troA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		5 / 12 LYS A 317
SER A 368
ASN A 370
LYS A 513
GLY A 515
 None
 0.56A 3q07B-5troA:
17.2		 3q07B-5troA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 12 SER A 314
SER A 368
ASN A 370
LYS A 513
THR A 514
GLY A 515
 None
 0.30A 3sh8A-5troA:
17.6		 3sh8A-5troA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 12 SER A 314
LYS A 317
SER A 368
ASN A 370
LYS A 513
GLY A 515
 None
 0.39A 3sh8B-5troA:
17.4		 3sh8B-5troA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 12 SER A 314
LYS A 317
SER A 368
ASN A 370
LYS A 513
TYR A 566
 None
 0.88A 3sh8B-5troA:
17.4		 3sh8B-5troA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		4 / 5 ILE A 410
THR A 427
THR A 428
PHE A 316
 None
 1.14A 3snfA-5troA:
undetectable		 3snfA-5troA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		4 / 6 ILE A 124
LEU A 113
ARG A 140
THR A 143
 None
 1.15A 3wg7A-5troA:
undetectable
3wg7J-5troA:
undetectable		 3wg7A-5troA:
21.23
3wg7J-5troA:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		3 / 3 ASN A  72
ASP A 245
ASN A 247
 None
 0.71A 4agaA-5troA:
undetectable		 4agaA-5troA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		5 / 12 ARG A 236
ARG A 169
VAL A 199
GLU A 200
VAL A 453
 None
None
None
None
CL  A 701 (-4.1A)
 1.25A 4danA-5troA:
undetectable
4danB-5troA:
undetectable		 4danA-5troA:
17.16
4danB-5troA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		7 / 12 LYS A 317
SER A 368
ASN A 370
LYS A 513
THR A 514
GLY A 515
THR A 516
 None
 0.59A 4euzA-5troA:
17.0		 4euzA-5troA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		5 / 10 SER A 368
ASN A 370
LYS A 513
THR A 514
GLY A 515
 None
 0.52A 4fh2A-5troA:
19.2		 4fh2A-5troA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 12 SER A 314
SER A 368
ASN A 370
LYS A 513
THR A 514
GLY A 515
 None
 0.36A 4n9kA-5troA:
17.1		 4n9kA-5troA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 12 SER A 314
SER A 368
ASN A 370
LYS A 513
THR A 514
GLY A 515
 None
 0.37A 4n9kB-5troA:
17.2		 4n9kB-5troA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		4 / 4 ALA A 553
VAL A 536
GLY A 313
THR A 315
 None
 1.06A 4ubeA-5troA:
undetectable		 4ubeA-5troA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_A_QDNA602_1
(CYTOCHROME P450 2D6)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		5 / 11 LEU A 242
GLY A 198
LEU A 197
GLU A 200
ALA A 177
 None
 1.18A 4wnuA-5troA:
undetectable		 4wnuA-5troA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		5 / 9 ILE A 181
GLY A 198
ILE A  68
ALA A  77
ARG A 169
 None
 1.25A 4yp2B-5troA:
undetectable		 4yp2B-5troA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		4 / 7 LYS A 152
TYR A 147
TYR A  83
LEU A 145
 None
 1.25A 4yv5B-5troA:
undetectable		 4yv5B-5troA:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		5 / 9 ILE A 181
GLY A 198
ILE A  68
ALA A  77
ARG A 169
 None
 1.26A 5cf9B-5troA:
undetectable		 5cf9B-5troA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 11 SER A 314
SER A 368
ASN A 370
LYS A 513
THR A 514
GLY A 515
 None
 0.33A 5ghzA-5troA:
17.1		 5ghzA-5troA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 10 SER A 314
SER A 368
ASN A 370
LYS A 513
THR A 514
GLY A 515
 None
 0.35A 5ghzB-5troA:
17.1		 5ghzB-5troA:
19.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		5 / 12 TRP A 351
ASN A 370
GLY A 515
THR A 516
GLN A 518
 None
 1.23A 5oj0A-5troA:
40.1		 5oj0A-5troA:
31.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 12 TRP A 351
SER A 368
ASN A 370
GLN A 425
GLY A 515
THR A 516
 None
 1.14A 5oj0A-5troA:
40.1		 5oj0A-5troA:
31.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		4 / 5 ARG A 341
MET A 373
THR A 371
LEU A 372
 None
 1.42A 5z86J-5troA:
undetectable		 5z86J-5troA:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 12 SER A 314
SER A 368
LYS A 513
THR A 514
GLY A 515
THR A 516
 None
 0.42A 6b5yB-5troA:
17.0		 6b5yB-5troA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 12 SER A 314
SER A 368
LYS A 513
THR A 514
GLY A 515
THR A 516
 None
 0.47A 6b5yD-5troA:
16.9		 6b5yD-5troA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 12 SER A 314
SER A 368
LYS A 513
THR A 514
GLY A 515
THR A 516
 None
 0.29A 6b68B-5troA:
16.9		 6b68B-5troA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		5 / 12 SER A 314
SER A 368
LYS A 513
GLY A 515
THR A 516
 None
 0.36A 6b68D-5troA:
17.0		 6b68D-5troA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 12 SER A 314
SER A 368
LYS A 513
THR A 514
GLY A 515
THR A 516
 None
 0.27A 6b69A-5troA:
17.0
6b69B-5troA:
16.8		 6b69A-5troA:
10.38
6b69B-5troA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 12 SER A 314
SER A 368
LYS A 513
THR A 514
GLY A 515
THR A 516
 None
 0.27A 6b69D-5troA:
16.9		 6b69D-5troA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 12 SER A 314
SER A 368
LYS A 513
THR A 514
GLY A 515
THR A 516
 None
 0.34A 6b6aB-5troA:
16.9		 6b6aB-5troA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 12 SER A 314
SER A 368
LYS A 513
THR A 514
GLY A 515
THR A 516
 None
 0.31A 6b6aD-5troA:
16.9		 6b6aD-5troA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 12 SER A 314
SER A 368
LYS A 513
THR A 514
GLY A 515
THR A 516
 None
 0.43A 6b6cA-5troA:
16.8		 6b6cA-5troA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 12 SER A 314
SER A 368
LYS A 513
THR A 514
GLY A 515
THR A 516
 None
 0.59A 6b6dA-5troA:
16.7		 6b6dA-5troA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 12 SER A 314
SER A 368
LYS A 513
THR A 514
GLY A 515
THR A 516
 None
 0.40A 6b6eA-5troA:
16.9		 6b6eA-5troA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		6 / 12 SER A 314
SER A 368
LYS A 513
THR A 514
GLY A 515
THR A 516
 None
 0.52A 6b6fA-5troA:
16.9		 6b6fA-5troA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F32_B_ACTB602_0
(AMINE OXIDASE LKCE)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		4 / 6 ASN A 532
TYR A 566
VAL A 536
THR A 516
 None
 1.25A 6f32B-5troA:
undetectable		 6f32B-5troA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tro PENICILLIN-BINDING
PROTEIN 1
(Staphylococcus
aureus) 		4 / 6 ILE A 124
LEU A 113
ARG A 140
THR A 143
 None
 1.14A 6nmfN-5troA:
undetectable
6nmfW-5troA:
undetectable		 6nmfN-5troA:
21.23
6nmfW-5troA:
7.94