SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tsb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)		 5tsb MEMBRANE PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ALA A 184
GLY A 182
GLY A 243
ILE A 196
GLY A 192
 None
 1.04A 1sqfA-5tsbA:
undetectable		 1sqfA-5tsbA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 5tsb MEMBRANE PROTEIN
(Bordetella
bronchiseptica) 		4 / 7 SER A 236
LEU A 224
ILE A 174
GLY A 227
 None
 0.96A 2v0mC-5tsbA:
undetectable		 2v0mC-5tsbA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 5tsb MEMBRANE PROTEIN
(Bordetella
bronchiseptica) 		4 / 7 GLY A 186
GLY A 182
THR A 201
ALA A  59
 None
 0.73A 3fpjB-5tsbA:
undetectable		 3fpjB-5tsbA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 5tsb MEMBRANE PROTEIN
(Bordetella
bronchiseptica) 		4 / 8 GLY A 197
THR A 201
MET A 183
GLY A 182
 None
 0.76A 4fo4B-5tsbA:
undetectable		 4fo4B-5tsbA:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5tsb MEMBRANE PROTEIN
(Bordetella
bronchiseptica) 		5 / 11 ALA A  59
ALA A 244
GLY A 192
ALA A 190
SER A 251
 None
 0.95A 4qvlK-5tsbA:
undetectable
4qvlL-5tsbA:
undetectable		 4qvlK-5tsbA:
22.83
4qvlL-5tsbA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5tsb MEMBRANE PROTEIN
(Bordetella
bronchiseptica) 		5 / 11 ALA A  59
ALA A 244
GLY A 192
ALA A 190
SER A 251
 None
 0.95A 4qvlY-5tsbA:
undetectable
4qvlZ-5tsbA:
undetectable		 4qvlY-5tsbA:
22.83
4qvlZ-5tsbA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5tsb MEMBRANE PROTEIN
(Bordetella
bronchiseptica) 		5 / 10 ALA A  59
ALA A 244
GLY A 192
ALA A 190
SER A 251
 None
 0.95A 4qvmY-5tsbA:
undetectable
4qvmZ-5tsbA:
undetectable		 4qvmY-5tsbA:
22.54
4qvmZ-5tsbA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5tsb MEMBRANE PROTEIN
(Bordetella
bronchiseptica) 		5 / 11 ALA A  59
ALA A 244
GLY A 192
ALA A 190
SER A 251
 None
 0.95A 4qw1K-5tsbA:
undetectable
4qw1L-5tsbA:
undetectable		 4qw1K-5tsbA:
22.33
4qw1L-5tsbA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5tsb MEMBRANE PROTEIN
(Bordetella
bronchiseptica) 		5 / 11 ALA A  59
ALA A 244
GLY A 192
ALA A 190
SER A 251
 None
 0.94A 5bxnK-5tsbA:
undetectable
5bxnL-5tsbA:
undetectable		 5bxnK-5tsbA:
22.83
5bxnL-5tsbA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5tsb MEMBRANE PROTEIN
(Bordetella
bronchiseptica) 		5 / 11 ALA A  59
ALA A 244
GLY A 192
ALA A 190
SER A 251
 None
 0.94A 5bxnY-5tsbA:
undetectable
5bxnZ-5tsbA:
undetectable		 5bxnY-5tsbA:
22.83
5bxnZ-5tsbA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5tsb MEMBRANE PROTEIN
(Bordetella
bronchiseptica) 		5 / 9 SER A 261
GLY A 263
ALA A 115
VAL A 129
ILE A 108
 None
 1.27A 5i3cA-5tsbA:
undetectable		 5i3cA-5tsbA:
26.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5tsb MEMBRANE PROTEIN
(Bordetella
bronchiseptica) 		3 / 3 GLY A 136
VAL A 187
MET A 183
 None
 0.56A 5ycpA-5tsbA:
undetectable		 5ycpA-5tsbA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 5tsb MEMBRANE PROTEIN
(Bordetella
bronchiseptica) 		5 / 9 ALA A 235
SER A 236
GLY A 237
ALA A 216
GLY A 212
 None
 1.17A 6bklE-5tsbA:
undetectable
6bklF-5tsbA:
undetectable
6bklG-5tsbA:
undetectable
6bklH-5tsbA:
undetectable		 6bklE-5tsbA:
7.12
6bklF-5tsbA:
7.12
6bklG-5tsbA:
7.12
6bklH-5tsbA:
7.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5tsb MEMBRANE PROTEIN
(Bordetella
bronchiseptica) 		5 / 10 VAL A 137
GLY A 267
SER A 103
ALA A 104
VAL A 273
 None
 1.33A 6hu9L-5tsbA:
undetectable
6hu9P-5tsbA:
undetectable
6hu9T-5tsbA:
undetectable		 6hu9L-5tsbA:
19.07
6hu9P-5tsbA:
21.29
6hu9T-5tsbA:
10.68