SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tt1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 5tt1 PUTATIVE SHORT-CHAIN
ALCOHOL
DEHYDROGENASE
(Burkholderia
multivorans) 		5 / 12 LEU A 137
PRO A 133
ILE A 138
LEU A  12
VAL A  36
 None
 0.88A 4gc9A-5tt1A:
5.8		 4gc9A-5tt1A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 5tt1 PUTATIVE SHORT-CHAIN
ALCOHOL
DEHYDROGENASE
(Burkholderia
multivorans) 		4 / 5 ARG A  31
TRP A  33
ILE A  11
ASN A  90
 None
 1.49A 4i00A-5tt1A:
undetectable		 4i00A-5tt1A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 5tt1 PUTATIVE SHORT-CHAIN
ALCOHOL
DEHYDROGENASE
(Burkholderia
multivorans) 		4 / 8 GLY A 144
ARG A 233
ASP A 229
TYR A 230
 None
 0.90A 5vlmA-5tt1A:
0.0		 5vlmA-5tt1A:
21.79