SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tta'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 5tta PUTATIVE EXPORTED
PROTEIN
(Clostridioides
difficile) 		4 / 6 GLN A 210
ILE A 204
TYR A 101
PHE A 214
 None
 1.47A 1e73M-5ttaA:
undetectable		 1e73M-5ttaA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I00_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 5tta PUTATIVE EXPORTED
PROTEIN
(Clostridioides
difficile) 		5 / 9 PHE A 259
ILE A 233
ASP A 109
GLY A 112
ASN A 266
 None
 1.37A 1i00B-5ttaA:
undetectable		 1i00B-5ttaA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 5tta PUTATIVE EXPORTED
PROTEIN
(Clostridioides
difficile) 		3 / 3 PRO A 150
ASP A 120
ASP A 218
 None
 0.79A 1sqfA-5ttaA:
undetectable		 1sqfA-5ttaA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 5tta PUTATIVE EXPORTED
PROTEIN
(Clostridioides
difficile) 		4 / 7 THR A  79
HIS A  82
GLY A 143
ASP A 141
 None
 1.01A 2ddwB-5ttaA:
undetectable		 2ddwB-5ttaA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 5tta PUTATIVE EXPORTED
PROTEIN
(Clostridioides
difficile) 		4 / 6 LEU A  67
LYS A 162
GLN A  75
ILE A  88
 None
 1.16A 2jn3A-5ttaA:
undetectable		 2jn3A-5ttaA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5tta PUTATIVE EXPORTED
PROTEIN
(Clostridioides
difficile) 		4 / 7 TYR A 101
CYH A 105
TYR A 160
ILE A  69
 None
 1.27A 2xz5B-5ttaA:
undetectable
2xz5E-5ttaA:
undetectable		 2xz5B-5ttaA:
23.02
2xz5E-5ttaA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPR_A_1KXA277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5tta PUTATIVE EXPORTED
PROTEIN
(Clostridioides
difficile) 		5 / 10 TYR A 252
ILE A 103
SER A 234
ILE A 232
TRP A 119
 None
 1.44A 3uprA-5ttaA:
2.0		 3uprA-5ttaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPR_C_1KXC277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5tta PUTATIVE EXPORTED
PROTEIN
(Clostridioides
difficile) 		5 / 10 TYR A 252
ILE A 103
SER A 234
ILE A 232
TRP A 119
 None
 1.42A 3uprC-5ttaA:
2.2		 3uprC-5ttaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5tta PUTATIVE EXPORTED
PROTEIN
(Clostridioides
difficile) 		5 / 12 CYH A 105
LEU A 216
VAL A 229
LEU A  90
TYR A 101
 None
 1.42A 4o8fB-5ttaA:
undetectable		 4o8fB-5ttaA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 5tta PUTATIVE EXPORTED
PROTEIN
(Clostridioides
difficile) 		4 / 6 ASP A 218
TYR A 156
PRO A 114
LEU A 106
 None
 1.10A 5bmvB-5ttaA:
undetectable		 5bmvB-5ttaA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5tta PUTATIVE EXPORTED
PROTEIN
(Clostridioides
difficile) 		4 / 6 TYR A 252
ILE A  69
TYR A 272
TYR A 108
 None
 1.48A 5igyA-5ttaA:
undetectable		 5igyA-5ttaA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_2
(CYCLIN-DEPENDENT
KINASE 6)		 5tta PUTATIVE EXPORTED
PROTEIN
(Clostridioides
difficile) 		3 / 3 LYS A 208
GLN A 201
ASN A 202
 None
 0.66A 5l2tA-5ttaA:
undetectable		 5l2tA-5ttaA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5tta PUTATIVE EXPORTED
PROTEIN
(Clostridioides
difficile) 		5 / 10 TYR A 252
ILE A 103
SER A 234
ILE A 232
TRP A 119
 None
 1.41A 5u98A-5ttaA:
undetectable		 5u98A-5ttaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_D_1KXD301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5tta PUTATIVE EXPORTED
PROTEIN
(Clostridioides
difficile) 		5 / 10 TYR A 252
ILE A 103
SER A 234
ILE A 232
TRP A 119
 None
 1.41A 5u98D-5ttaA:
2.2		 5u98D-5ttaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA609_0
(ALPHA-AMYLASE)		 5tta PUTATIVE EXPORTED
PROTEIN
(Clostridioides
difficile) 		4 / 7 GLY A 225
ASP A  77
TRP A  83
TYR A  76
 None
 1.17A 6ag0A-5ttaA:
undetectable		 6ag0A-5ttaA:
14.94