SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tte'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 129
THR B 131
PRO B 127
 None
 0.80A 1a7yA-5tteB:
undetectable		 1a7yA-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 131
PRO B 127
THR B 129
 None
 0.82A 1a7yB-5tteB:
undetectable		 1a7yB-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 129
THR B 131
PRO B 127
 None
 0.71A 1a7yB-5tteB:
undetectable		 1a7yB-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 TRP B 319
ALA B 479
VAL B 315
 None
 0.90A 1c4dA-5tteB:
undetectable
1c4dB-5tteB:
undetectable		 1c4dA-5tteB:
2.60
1c4dB-5tteB:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		4 / 6 CYH B 372
VAL B 374
HIS B 382
CYH B 389
 ZN  B 602 (-2.4A)
None
ZN  B 602 (-3.2A)
ZN  B 602 (-2.4A)
 1.30A 1ekjG-5tteB:
undetectable
1ekjH-5tteB:
undetectable		 1ekjG-5tteB:
15.30
1ekjH-5tteB:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 129
THR B 131
PRO B 127
 None
 0.80A 1fjaC-5tteB:
undetectable		 1fjaC-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 129
THR B 131
PRO B 127
 None
 0.80A 1fjaD-5tteB:
undetectable		 1fjaD-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 131
PRO B 127
THR B 129
 None
 0.77A 1i3wE-5tteB:
undetectable		 1i3wE-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 129
THR B 131
PRO B 127
 None
 0.80A 1i3wE-5tteB:
undetectable		 1i3wE-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 129
THR B 131
PRO B 127
 None
 0.81A 1i3wF-5tteB:
undetectable		 1i3wF-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 131
PRO B 127
THR B 129
 None
 0.74A 1i3wG-5tteB:
undetectable		 1i3wG-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 129
THR B 131
PRO B 127
 None
 0.82A 1i3wG-5tteB:
undetectable		 1i3wG-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 129
THR B 131
PRO B 127
 None
 0.80A 1i3wH-5tteB:
undetectable		 1i3wH-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 131
PRO B 127
THR B 129
 None
 0.86A 1mnvD-5tteB:
undetectable		 1mnvD-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 129
THR B 131
PRO B 127
 None
 0.83A 1mnvD-5tteB:
undetectable		 1mnvD-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 131
PRO B 127
THR B 129
 None
 0.86A 1ovfB-5tteB:
undetectable		 1ovfB-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 129
THR B 131
PRO B 127
 None
 0.83A 1qfiA-5tteB:
undetectable		 1qfiA-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 129
THR B 131
PRO B 127
 None
 0.72A 1qfiB-5tteB:
undetectable		 1qfiB-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 131
PRO B 127
THR B 129
 None
 0.76A 1unjF-5tteB:
undetectable		 1unjF-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 129
THR B 131
PRO B 127
 None
 0.79A 1unjF-5tteB:
undetectable		 1unjF-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 131
PRO B 127
THR B 129
 None
 0.77A 1unjL-5tteB:
undetectable		 1unjL-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 129
THR B 131
PRO B 127
 None
 0.79A 1unjL-5tteB:
undetectable		 1unjL-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 131
PRO B 127
THR B 129
 None
 0.83A 1unjR-5tteB:
undetectable		 1unjR-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 129
THR B 131
PRO B 127
 None
 0.78A 1unjR-5tteB:
undetectable		 1unjR-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 129
THR B 131
PRO B 127
 None
 0.80A 1unjW-5tteB:
undetectable		 1unjW-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 131
PRO B 127
THR B 129
 None
 0.77A 1unjX-5tteB:
undetectable		 1unjX-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 129
THR B 131
PRO B 127
 None
 0.79A 1unjX-5tteB:
undetectable		 1unjX-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 131
PRO B 127
THR B 129
 None
 0.78A 1unmE-5tteB:
undetectable		 1unmE-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 129
THR B 131
PRO B 127
 None
 0.77A 1unmE-5tteB:
undetectable		 1unmE-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 131
PRO B 127
THR B 129
 None
 0.79A 1unmF-5tteB:
undetectable		 1unmF-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 129
THR B 131
PRO B 127
 None
 0.74A 1unmF-5tteB:
undetectable		 1unmF-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 131
PRO B 127
THR B 129
 None
 0.66A 209dC-5tteB:
undetectable		 209dC-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 THR B 129
THR B 131
PRO B 127
 None
 0.72A 209dC-5tteB:
undetectable		 209dC-5tteB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		5 / 12 ARG B 247
TYR B 258
ILE B 130
ILE B 133
LEU B 201
 None
 1.26A 2bjfA-5tteB:
undetectable		 2bjfA-5tteB:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		4 / 6 TYR B 474
TYR B 481
TYR B 547
LEU B 482
 None
 1.14A 2w98A-5tteB:
undetectable
2w98B-5tteB:
undetectable		 2w98A-5tteB:
19.82
2w98B-5tteB:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 CYH B 372
CYH B 389
HIS B 382
 ZN  B 602 (-2.4A)
ZN  B 602 (-2.4A)
ZN  B 602 (-3.2A)
 0.88A 3dtuB-5tteB:
undetectable		 3dtuB-5tteB:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 CYH B 372
CYH B 389
HIS B 382
 ZN  B 602 (-2.4A)
ZN  B 602 (-2.4A)
ZN  B 602 (-3.2A)
 0.86A 3dtuD-5tteB:
undetectable		 3dtuD-5tteB:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		5 / 12 CYH B 357
GLY B 356
ASN B 423
ASN B 358
GLY B 355
 None
 1.00A 3huoB-5tteB:
undetectable		 3huoB-5tteB:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 5tte E3 UBIQUITIN-PROTEIN
LIGASE ARIH1
(Homo
sapiens) 		3 / 3 TYR B 529
ASP B 527
GLN B 526
 None
 0.75A 6g1pA-5tteB:
undetectable		 6g1pA-5tteB:
19.82