SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tu9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA142_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 5tu9 ACCUMULATION
ASSOCIATED PROTEIN
AAP G58-SPACER-G513
(VARIANT
G5-SPACER-CONSENSUS
G5)
(Staphylococcus
epidermidis) 		4 / 5 GLU A  11
PRO A  13
ILE A  12
GLY A  38
 None
 0.86A 2qeuA-5tu9A:
undetectable
2qeuC-5tu9A:
undetectable		 2qeuA-5tu9A:
18.40
2qeuC-5tu9A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5tu9 ACCUMULATION
ASSOCIATED PROTEIN
AAP G58-SPACER-G513
(VARIANT
G5-SPACER-CONSENSUS
G5)
(Staphylococcus
epidermidis) 		4 / 6 ASN A  21
GLU A  28
GLU A  29
GLU A  75
 None
 0.94A 4mi4A-5tu9A:
undetectable		 4mi4A-5tu9A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5tu9 ACCUMULATION
ASSOCIATED PROTEIN
AAP G58-SPACER-G513
(VARIANT
G5-SPACER-CONSENSUS
G5)
(Staphylococcus
epidermidis) 		4 / 8 ASN A  21
GLU A  28
GLU A  29
GLU A  75
 None
 0.91A 4mj8A-5tu9A:
undetectable
4mj8C-5tu9A:
undetectable		 4mj8A-5tu9A:
19.53
4mj8C-5tu9A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5tu9 ACCUMULATION
ASSOCIATED PROTEIN
AAP G58-SPACER-G513
(VARIANT
G5-SPACER-CONSENSUS
G5)
(Staphylococcus
epidermidis) 		4 / 7 ASN A  21
GLU A  28
GLU A  29
GLU A  75
 None
 1.08A 4mj8C-5tu9A:
undetectable		 4mj8C-5tu9A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5tu9 ACCUMULATION
ASSOCIATED PROTEIN
AAP G58-SPACER-G513
(VARIANT
G5-SPACER-CONSENSUS
G5)
(Staphylococcus
epidermidis) 		4 / 7 ASN A  21
GLU A  28
GLU A  29
GLU A  75
 None
 1.04A 4r87I-5tu9A:
undetectable		 4r87I-5tu9A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I5Z_D_SAMD401_0
(O-METHYLTRANSFERASE
1)		 5tu9 ACCUMULATION
ASSOCIATED PROTEIN
AAP G58-SPACER-G513
(VARIANT
G5-SPACER-CONSENSUS
G5)
(Staphylococcus
epidermidis) 		5 / 11 GLY A  78
GLY A  27
LEU A  24
ASP A  23
ASP A 111
 None
 1.21A 6i5zD-5tu9A:
undetectable		 6i5zD-5tu9A:
19.58