SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tud'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 5tud ANTI-5-HT2B FAB
HEAVY CHAIN
(Mus
musculus) 		3 / 3 ARG C  63
GLU C  46
ASN C  61
 None
 0.91A 4ip7D-5tudC:
undetectable		 4ip7D-5tudC:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 5tud ANTI-5-HT2B FAB
HEAVY CHAIN
(Mus
musculus) 		3 / 3 TYR C  94
GLN C  43
TRP C  47
 None
 0.94A 4kn2C-5tudC:
undetectable		 4kn2C-5tudC:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_A_DAHA60_1
(PUTATIVE CYTOCHROME
C)		 5tud ANTI-5-HT2B FAB
HEAVY CHAIN
(Mus
musculus) 		4 / 6 MET C  81
ASN C  77
VAL C  72
LEU C  70
 None
 1.17A 5xdhA-5tudC:
undetectable
5xdhC-5tudC:
undetectable		 5xdhA-5tudC:
16.11
5xdhC-5tudC:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_B_DAHB60_1
(PUTATIVE CYTOCHROME
C)		 5tud ANTI-5-HT2B FAB
HEAVY CHAIN
(Mus
musculus) 		4 / 5 MET C  81
ASN C  77
VAL C  72
LEU C  70
 None
 1.12A 5xdhB-5tudC:
undetectable		 5xdhB-5tudC:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 5tud ANTI-5-HT2B FAB
HEAVY CHAIN
(Mus
musculus) 		4 / 6 MET C  81
ASN C  77
VAL C  72
LEU C  70
 None
 1.05A 5xdhA-5tudC:
undetectable
5xdhC-5tudC:
undetectable		 5xdhA-5tudC:
16.11
5xdhC-5tudC:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_D_DAHD60_1
(PUTATIVE CYTOCHROME
C)		 5tud ANTI-5-HT2B FAB
HEAVY CHAIN
(Mus
musculus) 		4 / 5 MET C  81
ASN C  77
VAL C  72
LEU C  70
 None
 1.19A 5xdhD-5tudC:
undetectable		 5xdhD-5tudC:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 5tud ANTI-5-HT2B FAB
HEAVY CHAIN
(Mus
musculus) 		5 / 12 VAL C 221
THR C 219
VAL C 225
GLY C 132
VAL C 166
 None
 1.12A 6drzA-5tudC:
undetectable		 6drzA-5tudC:
17.35