SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tuj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5tuj ANCESTRAL PROTEIN
CDT-ANC1
(unidentified) 		4 / 8 PHE C 151
ALA C 177
VAL C 115
VAL C 200
 None
 0.75A 1epbB-5tujC:
undetectable		 1epbB-5tujC:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 5tuj ANCESTRAL PROTEIN
CDT-ANC1
(unidentified) 		5 / 12 GLU C 169
LYS C 116
ALA C 166
ALA C 148
VAL C 136
 None
 1.24A 3nvkF-5tujC:
undetectable
3nvkJ-5tujC:
undetectable		 3nvkF-5tujC:
undetectable
3nvkJ-5tujC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 5tuj ANCESTRAL PROTEIN
CDT-ANC1
(unidentified) 		4 / 4 THR C  15
GLY C 216
ASP C 101
SER C  14
 None
 1.39A 4rfqA-5tujC:
undetectable		 4rfqA-5tujC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_F_MN9F401_0
(N-ACETYLNEURAMINATE
LYASE)		 5tuj ANCESTRAL PROTEIN
CDT-ANC1
(unidentified) 		4 / 5 LEU C  52
ASP C  49
TYR C 237
LEU C 240
 None
 1.27A 4wozF-5tujC:
undetectable
4wozH-5tujC:
undetectable		 4wozF-5tujC:
undetectable
4wozH-5tujC:
undetectable