SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tup'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_B_BEZB264_0
(ECHA1_1)		 5tup PROLIFERATING CELL
NUCLEAR ANTIGEN
(Aspergillus
fumigatus) 		4 / 7 ILE A 116
LEU A 101
ALA A  81
ALA A  82
 None
 0.83A 3r9tB-5tupA:
undetectable		 3r9tB-5tupA:
21.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VKX_A_T3A301_1
(PROLIFERATING CELL
NUCLEAR ANTIGEN)		 5tup PROLIFERATING CELL
NUCLEAR ANTIGEN
(Aspergillus
fumigatus) 		4 / 6 MET A  40
LEU A  47
PRO A 234
TYR A 249
 None
 0.64A 3vkxA-5tupA:
36.6		 3vkxA-5tupA:
53.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 5tup PROLIFERATING CELL
NUCLEAR ANTIGEN
(Aspergillus
fumigatus) 		5 / 12 LEU A  88
VAL A  78
LEU A 118
ILE A  70
LEU A   2
 None
 1.19A 5ienA-5tupA:
undetectable		 5ienA-5tupA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_2
(PROTEIN CYP51)		 5tup PROLIFERATING CELL
NUCLEAR ANTIGEN
(Aspergillus
fumigatus) 		4 / 6 TYR A 239
LEU A  47
PHE A 248
LEU A 236
 None
 1.22A 5tl8A-5tupA:
undetectable		 5tl8A-5tupA:
20.77