SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tuv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_A_ADNA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 5tuv TRANSCRIPTION FACTOR
DP1
(Homo
sapiens) 		5 / 10 PHE A 261
ASP A 295
ILE A 297
VAL A 299
LEU A 259
 None
 1.35A 3ay0A-5tuvA:
undetectable		 3ay0A-5tuvA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_E_SC2E1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 5tuv TRANSCRIPTION FACTOR
DP1
TRANSCRIPTION FACTOR
E2F5
(Homo
sapiens) 		3 / 3 VAL B 126
GLN A 200
CYH A 202
 None
 0.75A 5icxA-5tuvB:
undetectable
5icxE-5tuvB:
undetectable		 5icxA-5tuvB:
20.19
5icxE-5tuvB:
7.69