SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tvg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		4 / 7 VAL A  11
LEU A  32
VAL A  28
LEU A 118
 None
 0.87A 1cqpA-5tvgA:
4.3
1cqpB-5tvgA:
3.7		 1cqpA-5tvgA:
19.20
1cqpB-5tvgA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_A_ESTA351_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 12 VAL A  26
GLY A  27
LEU A 442
GLY A  22
LEU A 437
 None
 1.12A 1fduA-5tvgA:
2.0		 1fduA-5tvgA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 12 GLY A 271
GLU A 274
LEU A 266
ILE A 312
HIS A  91
 None
 1.14A 1kyvA-5tvgA:
4.4
1kyvE-5tvgA:
4.3		 1kyvA-5tvgA:
14.97
1kyvE-5tvgA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 12 HIS A  91
GLY A 271
GLU A 274
LEU A 266
ILE A 312
 None
 1.15A 1kyvB-5tvgA:
4.4
1kyvC-5tvgA:
3.9		 1kyvB-5tvgA:
14.97
1kyvC-5tvgA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 12 HIS A  91
GLY A 271
GLU A 274
LEU A 266
ILE A 312
 None
 1.18A 1kyvC-5tvgA:
3.7
1kyvD-5tvgA:
4.5		 1kyvC-5tvgA:
14.97
1kyvD-5tvgA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 12 HIS A  91
GLY A 271
GLU A 274
LEU A 266
ILE A 312
 None
 1.19A 1kyvD-5tvgA:
4.5
1kyvE-5tvgA:
4.3		 1kyvD-5tvgA:
14.97
1kyvE-5tvgA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		3 / 3 ASP A  73
LEU A  67
LEU A  69
 None
 0.68A 1np1B-5tvgA:
undetectable		 1np1B-5tvgA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		4 / 8 THR A  63
ALA A  65
LEU A  67
VAL A  38
 None
 0.67A 1sn5C-5tvgA:
undetectable		 1sn5C-5tvgA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		4 / 7 MET A 282
GLN A 290
PHE A 279
ARG A 257
 None
 1.25A 1t9wA-5tvgA:
undetectable		 1t9wA-5tvgA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 12 ASN A 149
LEU A 127
ILE A 128
LEU A  32
ALA A  31
 None
 0.94A 2aclG-5tvgA:
undetectable		 2aclG-5tvgA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 11 SER A 196
ALA A 215
GLY A 205
THR A 206
ALA A 207
 None
 1.16A 2f16H-5tvgA:
undetectable
2f16I-5tvgA:
undetectable		 2f16H-5tvgA:
22.01
2f16I-5tvgA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 11 SER A 196
ALA A 215
GLY A 205
THR A 206
ALA A 207
 None
 1.16A 2f16V-5tvgA:
undetectable
2f16W-5tvgA:
undetectable		 2f16V-5tvgA:
22.01
2f16W-5tvgA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_B_PPFB3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		4 / 7 ARG A 265
HIS A  91
SER A 269
ASP A 364
 UDP  A 501 (-3.9A)
None
None
GOL  A 504 (-3.3A)
 1.50A 2rk8B-5tvgA:
undetectable		 2rk8B-5tvgA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		4 / 5 PHE A  99
PHE A  81
LEU A  86
PHE A  90
 None
 1.33A 2y69C-5tvgA:
undetectable
2y69J-5tvgA:
undetectable		 2y69C-5tvgA:
19.11
2y69J-5tvgA:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		4 / 5 PHE A  99
PHE A  81
LEU A  86
PHE A  90
 None
 1.34A 3abmC-5tvgA:
undetectable
3abmJ-5tvgA:
undetectable		 3abmC-5tvgA:
19.11
3abmJ-5tvgA:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		4 / 5 PHE A  99
PHE A  81
LEU A  86
PHE A  90
 None
 1.33A 3abmP-5tvgA:
undetectable
3abmW-5tvgA:
undetectable		 3abmP-5tvgA:
19.11
3abmW-5tvgA:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		4 / 5 PHE A  99
PHE A  81
LEU A  86
PHE A  90
 None
 1.24A 3ag3C-5tvgA:
undetectable
3ag3J-5tvgA:
undetectable		 3ag3C-5tvgA:
19.11
3ag3J-5tvgA:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 11 SER A 196
ALA A 215
GLY A 205
THR A 206
ALA A 207
 None
 1.18A 3mg0H-5tvgA:
undetectable
3mg0I-5tvgA:
undetectable		 3mg0H-5tvgA:
22.01
3mg0I-5tvgA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 11 SER A 196
ALA A 215
GLY A 205
THR A 206
ALA A 207
 None
 1.15A 3mg0V-5tvgA:
undetectable
3mg0W-5tvgA:
undetectable		 3mg0V-5tvgA:
22.01
3mg0W-5tvgA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		4 / 8 THR A  63
ALA A  65
LEU A  67
VAL A  38
 None
 0.70A 4ik6B-5tvgA:
undetectable		 4ik6B-5tvgA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		3 / 3 SER A  82
TYR A 107
PRO A  88
 None
 0.72A 4k8cA-5tvgA:
2.6		 4k8cA-5tvgA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		3 / 3 SER A 269
TYR A 268
PRO A 158
 None
 0.95A 4k8cA-5tvgA:
2.6		 4k8cA-5tvgA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		3 / 3 SER A  82
TYR A 107
PRO A  88
 None
 0.70A 4kahA-5tvgA:
4.1		 4kahA-5tvgA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		3 / 3 SER A 269
TYR A 268
PRO A 158
 None
 0.97A 4kahA-5tvgA:
4.1		 4kahA-5tvgA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		3 / 3 SER A  82
TYR A 107
PRO A  88
 None
 0.70A 4kahB-5tvgA:
5.0		 4kahB-5tvgA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		3 / 3 SER A 269
TYR A 268
PRO A 158
 None
 0.96A 4kahB-5tvgA:
5.0		 4kahB-5tvgA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		3 / 3 SER A  82
TYR A 107
PRO A  88
 None
 0.73A 4kanA-5tvgA:
5.4		 4kanA-5tvgA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		3 / 3 SER A 269
TYR A 268
PRO A 158
 None
 0.96A 4kanA-5tvgA:
5.4		 4kanA-5tvgA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		3 / 3 SER A  82
TYR A 107
PRO A  88
 None
 0.72A 4kanB-5tvgA:
3.7		 4kanB-5tvgA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		3 / 3 SER A 269
TYR A 268
PRO A 158
 None
 0.95A 4kanB-5tvgA:
3.7		 4kanB-5tvgA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		3 / 3 SER A  82
TYR A 107
PRO A  88
 None
 0.70A 4kbeA-5tvgA:
5.4		 4kbeA-5tvgA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		3 / 3 SER A 269
TYR A 268
PRO A 158
 None
 0.95A 4kbeA-5tvgA:
5.4		 4kbeA-5tvgA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		3 / 3 SER A  82
TYR A 107
PRO A  88
 None
 0.71A 4kbeB-5tvgA:
3.9		 4kbeB-5tvgA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		3 / 3 SER A 269
TYR A 268
PRO A 158
 None
 0.92A 4kbeB-5tvgA:
3.9		 4kbeB-5tvgA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		3 / 3 SER A  82
TYR A 107
PRO A  88
 None
 0.70A 4lbgA-5tvgA:
2.7		 4lbgA-5tvgA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		3 / 3 SER A  82
TYR A 107
PRO A  88
 None
 0.71A 4lbgB-5tvgA:
3.7		 4lbgB-5tvgA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 12 VAL A 147
LEU A 145
ARG A 143
LEU A 118
ALA A 139
 None
 1.05A 4o1zB-5tvgA:
undetectable		 4o1zB-5tvgA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		3 / 3 SER A 443
ASP A 447
GLN A  34
 None
GOL  A 505 (-3.7A)
GOL  A 505 (-3.0A)
 0.96A 4oltA-5tvgA:
undetectable
4oltB-5tvgA:
undetectable		 4oltA-5tvgA:
20.52
4oltB-5tvgA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 12 SER A 196
ALA A 215
GLY A 205
THR A 206
ALA A 207
 None
 1.17A 4qvpH-5tvgA:
undetectable
4qvpI-5tvgA:
undetectable		 4qvpH-5tvgA:
20.75
4qvpI-5tvgA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 12 SER A 196
ALA A 215
GLY A 205
THR A 206
ALA A 207
 None
 1.17A 4qvpV-5tvgA:
undetectable
4qvpW-5tvgA:
undetectable		 4qvpV-5tvgA:
20.75
4qvpW-5tvgA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 11 SER A 196
ALA A 215
GLY A 205
THR A 206
ALA A 207
 None
 1.15A 4qvvH-5tvgA:
undetectable		 4qvvH-5tvgA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 11 SER A 196
ALA A 215
GLY A 205
THR A 206
ALA A 207
 None
 1.15A 4qvvV-5tvgA:
undetectable		 4qvvV-5tvgA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 12 SER A 196
ALA A 215
GLY A 205
THR A 206
ALA A 207
 None
 1.19A 4qvyV-5tvgA:
undetectable
4qvyW-5tvgA:
undetectable		 4qvyV-5tvgA:
20.75
4qvyW-5tvgA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 11 SER A 196
ALA A 215
GLY A 205
THR A 206
ALA A 207
 None
 1.18A 4qw0H-5tvgA:
undetectable
4qw0I-5tvgA:
undetectable		 4qw0H-5tvgA:
20.75
4qw0I-5tvgA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 11 SER A 196
ALA A 215
GLY A 205
THR A 206
ALA A 207
 None
 1.18A 4qw0V-5tvgA:
undetectable
4qw0W-5tvgA:
undetectable		 4qw0V-5tvgA:
20.75
4qw0W-5tvgA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 12 SER A 196
ALA A 215
GLY A 205
THR A 206
ALA A 207
 None
 1.16A 4qw1H-5tvgA:
undetectable
4qw1I-5tvgA:
undetectable		 4qw1H-5tvgA:
20.75
4qw1I-5tvgA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 12 SER A 196
ALA A 215
GLY A 205
THR A 206
ALA A 207
 None
 1.16A 4qw1V-5tvgA:
undetectable
4qw1W-5tvgA:
undetectable		 4qw1V-5tvgA:
20.75
4qw1W-5tvgA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTR_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 11 GLY A 365
PHE A 159
TYR A 198
ASP A 191
PRO A 160
 GOL  A 504 (-3.7A)
None
None
None
None
 1.31A 4rtrA-5tvgA:
2.1		 4rtrA-5tvgA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		4 / 5 ILE A 157
SER A  82
HIS A 134
ASP A 267
 None
 1.35A 4rzvB-5tvgA:
undetectable		 4rzvB-5tvgA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 11 SER A 196
ALA A 215
GLY A 205
THR A 206
ALA A 207
 None
 1.17A 5bxnH-5tvgA:
undetectable
5bxnI-5tvgA:
undetectable		 5bxnH-5tvgA:
20.75
5bxnI-5tvgA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 11 SER A 196
ALA A 215
GLY A 205
THR A 206
ALA A 207
 None
 1.17A 5bxnV-5tvgA:
undetectable
5bxnW-5tvgA:
undetectable		 5bxnV-5tvgA:
20.75
5bxnW-5tvgA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 12 SER A 196
ALA A 215
GLY A 205
THR A 206
ALA A 207
 None
 1.16A 5cz7V-5tvgA:
undetectable
5cz7W-5tvgA:
undetectable		 5cz7V-5tvgA:
20.75
5cz7W-5tvgA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 10 LEU A 118
ALA A 120
ARG A   3
GLY A 146
LEU A 145
 None
 1.40A 5dxbA-5tvgA:
undetectable		 5dxbA-5tvgA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		3 / 3 THR A 188
ASP A 189
ALA A 190
 None
 0.10A 5g5gB-5tvgA:
undetectable		 5g5gB-5tvgA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 12 SER A 196
ALA A 215
GLY A 205
THR A 206
ALA A 207
 None
 1.18A 5l5fH-5tvgA:
undetectable
5l5fI-5tvgA:
undetectable		 5l5fH-5tvgA:
20.75
5l5fI-5tvgA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 12 SER A 196
ALA A 215
GLY A 205
THR A 206
ALA A 207
 None
 1.18A 5l5fV-5tvgA:
undetectable
5l5fW-5tvgA:
undetectable		 5l5fV-5tvgA:
20.75
5l5fW-5tvgA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 12 SER A 196
ALA A 215
GLY A 205
THR A 206
ALA A 207
 None
 1.15A 5l66H-5tvgA:
undetectable
5l66I-5tvgA:
undetectable		 5l66H-5tvgA:
20.75
5l66I-5tvgA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 12 SER A 196
ALA A 215
GLY A 205
THR A 206
ALA A 207
 None
 1.15A 5l66V-5tvgA:
undetectable
5l66W-5tvgA:
undetectable		 5l66V-5tvgA:
20.75
5l66W-5tvgA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_2
(TUBULIN BETA-2B
CHAIN)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 12 LEU A 442
LEU A 437
LEU A 368
ILE A 234
ALA A 375
 None
None
UDP  A 501 (-3.9A)
GOL  A 503 (-4.4A)
None
 1.15A 5nm5B-5tvgA:
undetectable		 5nm5B-5tvgA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_A_EF2A202_0
(CEREBLON ISOFORM 4)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		4 / 7 PRO A 160
PHE A  90
TRP A  87
TYR A 268
 None
 1.43A 5oh1A-5tvgA:
undetectable		 5oh1A-5tvgA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		4 / 5 PHE A  99
PHE A  81
LEU A  86
PHE A  90
 None
 1.26A 5wauC-5tvgA:
undetectable
5wauJ-5tvgA:
undetectable		 5wauC-5tvgA:
19.11
5wauJ-5tvgA:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		4 / 5 PHE A  99
PHE A  81
LEU A  86
PHE A  90
 None
 1.25A 5wauc-5tvgA:
undetectable
5wauj-5tvgA:
undetectable		 5wauc-5tvgA:
19.11
5wauj-5tvgA:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		4 / 5 PHE A  99
PHE A  81
LEU A  86
PHE A  90
 None
 1.27A 5xdqC-5tvgA:
undetectable
5xdqJ-5tvgA:
undetectable		 5xdqC-5tvgA:
19.11
5xdqJ-5tvgA:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		4 / 5 PHE A  99
PHE A  81
LEU A  86
PHE A  90
 None
 1.26A 5xdqP-5tvgA:
undetectable
5xdqW-5tvgA:
undetectable		 5xdqP-5tvgA:
19.11
5xdqW-5tvgA:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 12 PHE A 177
LEU A 165
ILE A 199
LEU A 108
TYR A 104
 None
 1.44A 5ycpA-5tvgA:
undetectable		 5ycpA-5tvgA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)
(Burkholderia
vietnamiensis) 		5 / 9 ALA A  21
SER A  20
ALA A  25
GLY A  23
GLY A  27
 None
 1.08A 6bklE-5tvgA:
undetectable
6bklF-5tvgA:
undetectable
6bklG-5tvgA:
undetectable
6bklH-5tvgA:
undetectable		 6bklE-5tvgA:
5.82
6bklF-5tvgA:
5.82
6bklG-5tvgA:
5.82
6bklH-5tvgA:
5.82