SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tzm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_E_CLME221_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	5tzm	OBSCURIN (Homo sapiens)	3 / 3	PHE A 78 CYH A 25 HIS A 61	None	1.12A	3u9fF-5tzmA: undetectable	3u9fF-5tzmA: 18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_I_CLMI221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	5tzm	OBSCURIN (Homo sapiens)	3 / 3	PHE A 78 CYH A 25 HIS A 61	None	1.12A	3u9fG-5tzmA: undetectable	3u9fG-5tzmA: 18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_K_CLMK221_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	5tzm	OBSCURIN (Homo sapiens)	3 / 3	PHE A 78 CYH A 25 HIS A 61	None	1.12A	3u9fL-5tzmA: undetectable	3u9fL-5tzmA: 18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_R_CLMR221_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	5tzm	OBSCURIN (Homo sapiens)	3 / 3	PHE A 78 CYH A 25 HIS A 61	None	1.18A	3u9fS-5tzmA: undetectable	3u9fS-5tzmA: 18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HPU_C_IPHC101_0 (INSULIN, CHAIN A INSULIN, CHAIN B)	5tzm	OBSCURIN (Homo sapiens)	4 / 6	CYH A 80 LEU A 4 CYH A 25 LEU A 27	None	1.14A	5hpuC-5tzmA: undetectable 5hpuD-5tzmA: undetectable	5hpuC-5tzmA: 10.20 5hpuD-5tzmA: 18.31

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3U9F_E_CLME221_1","CHLORAMPHENICOL ACETYLTRANSFERASE","5tzm","OBSCURIN","Homo sapiens",3,"PHE A  78;CYH A  25;HIS A  61","None","1.12A","3u9fF-5tzmA:undetectable","3u9fF-5tzmA:18.48"],["3U9F_I_CLMI221_0","CHLORAMPHENICOL ACETYLTRANSFERASE","5tzm","OBSCURIN","Homo sapiens",3,"PHE A  78;CYH A  25;HIS A  61","None","1.12A","3u9fG-5tzmA:undetectable","3u9fG-5tzmA:18.48"],["3U9F_K_CLMK221_1","CHLORAMPHENICOL ACETYLTRANSFERASE","5tzm","OBSCURIN","Homo sapiens",3,"PHE A  78;CYH A  25;HIS A  61","None","1.12A","3u9fL-5tzmA:undetectable","3u9fL-5tzmA:18.48"],["3U9F_R_CLMR221_1","CHLORAMPHENICOL ACETYLTRANSFERASE","5tzm","OBSCURIN","Homo sapiens",3,"PHE A  78;CYH A  25;HIS A  61","None","1.18A","3u9fS-5tzmA:undetectable","3u9fS-5tzmA:18.48"],["5HPU_C_IPHC101_0","INSULIN, CHAIN A;INSULIN, CHAIN B","5tzm","OBSCURIN","Homo sapiens",4,"CYH A  80;LEU A   4;CYH A  25;LEU A  27","None","1.14A","5hpuC-5tzmA:undetectable;5hpuD-5tzmA:undetectable","5hpuC-5tzmA:10.20;5hpuD-5tzmA:18.31"]]