SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5tzn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAW_A_SUZA91_1
(SEGMENT POLARITY
PROTEIN DISHEVELLED
HOMOLOG DVL-1)		 5tzn KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER
1B ALLELE B
(Mus
musculus) 		5 / 11 LEU A 156
GLY A 155
ILE A 154
ILE A 132
LEU A 178
 None
None
None
None
NAG  A 302 (-4.7A)
 0.94A 2kawA-5tznA:
undetectable		 2kawA-5tznA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)		 5tzn GLYCOPROTEIN FAMILY
PROTEIN M12
(Murid
betaherpesvirus
1) 		4 / 7 THR F 129
PRO F 128
SER F 123
GLU F  91
 None
 1.05A 2v41E-5tznF:
undetectable
2v41F-5tznF:
undetectable		 2v41E-5tznF:
21.22
2v41F-5tznF:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5tzn KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER
1B ALLELE B
GLYCOPROTEIN FAMILY
PROTEIN M12
(Mus
musculus;
Murid
betaherpesvirus
1) 		4 / 5 TYR A 158
ARG F  49
MET A 163
THR A 161
 None
 1.37A 3abkN-5tznA:
undetectable
3abkW-5tznA:
undetectable		 3abkN-5tznA:
13.13
3abkW-5tznA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5tzn KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER
1B ALLELE B
GLYCOPROTEIN FAMILY
PROTEIN M12
(Mus
musculus;
Murid
betaherpesvirus
1) 		4 / 5 TYR A 158
ARG F  49
MET A 163
THR A 161
 None
 1.44A 3ag1J-5tznA:
undetectable		 3ag1J-5tznA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5tzn KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER
1B ALLELE B
GLYCOPROTEIN FAMILY
PROTEIN M12
(Mus
musculus;
Murid
betaherpesvirus
1) 		4 / 5 TYR A 158
ARG F  49
MET A 163
THR A 161
 None
 1.36A 3ag2J-5tznA:
undetectable		 3ag2J-5tznA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tzn KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER
1B ALLELE B
GLYCOPROTEIN FAMILY
PROTEIN M12
(Mus
musculus;
Murid
betaherpesvirus
1) 		4 / 5 TYR A 158
ARG F  49
MET A 163
THR A 161
 None
 1.34A 5w97J-5tznA:
undetectable		 5w97J-5tznA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tzn KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER
1B ALLELE B
GLYCOPROTEIN FAMILY
PROTEIN M12
(Mus
musculus;
Murid
betaherpesvirus
1) 		4 / 5 TYR A 158
ARG F  49
MET A 163
THR A 161
 None
 1.40A 5x1bW-5tznA:
undetectable		 5x1bW-5tznA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tzn KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER
1B ALLELE B
GLYCOPROTEIN FAMILY
PROTEIN M12
(Mus
musculus;
Murid
betaherpesvirus
1) 		4 / 5 TYR A 158
ARG F  49
MET A 163
THR A 161
 None
 1.39A 5x1fW-5tznA:
undetectable		 5x1fW-5tznA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 5tzn KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER
1B ALLELE B
(Mus
musculus) 		5 / 12 GLU A 137
ILE A 132
LEU A 156
GLY A 155
ALA A 172
 None
 1.19A 5x5qB-5tznA:
undetectable		 5x5qB-5tznA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5tzn KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER
1B ALLELE B
GLYCOPROTEIN FAMILY
PROTEIN M12
(Mus
musculus;
Murid
betaherpesvirus
1) 		4 / 5 TYR A 158
ARG F  49
MET A 163
THR A 161
 None
 1.42A 6nknJ-5tznA:
undetectable		 6nknJ-5tznA:
18.25