SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u02'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 5u02 GLYCOSYL TRANSFERASE
(Staphylococcus
aureus) 		4 / 7 LEU A 472
THR A 473
PRO A 474
GLY A 514
 None
IMD  A 601 (-3.8A)
None
None
 1.05A 2ddwB-5u02A:
undetectable		 2ddwB-5u02A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5u02 GLYCOSYL TRANSFERASE
(Staphylococcus
aureus) 		4 / 7 GLN A 323
TYR A 324
TYR A 383
ILE A 437
 None
 1.34A 2ph9A-5u02A:
undetectable
2ph9B-5u02A:
undetectable		 2ph9A-5u02A:
18.75
2ph9B-5u02A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5u02 GLYCOSYL TRANSFERASE
(Staphylococcus
aureus) 		4 / 5 GLN A 283
THR A 259
HIS A 253
LEU A 250
 None
 1.38A 2zj0A-5u02A:
undetectable		 2zj0A-5u02A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 5u02 GLYCOSYL TRANSFERASE
(Staphylococcus
aureus) 		4 / 4 PRO A 474
THR A 473
GLY A 510
THR A 509
 None
IMD  A 601 (-3.8A)
None
None
 0.94A 3ib1A-5u02A:
undetectable		 3ib1A-5u02A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 5u02 GLYCOSYL TRANSFERASE
(Staphylococcus
aureus) 		4 / 7 GLN A 537
GLU A 458
PHE A 362
PRO A 474
 None
IMD  A 601 (-3.0A)
None
None
 1.06A 3ql6A-5u02A:
undetectable		 3ql6A-5u02A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5u02 GLYCOSYL TRANSFERASE
(Staphylococcus
aureus) 		4 / 5 GLU A 443
GLU A 434
PHE A 432
TYR A 399
 None
 1.07A 4a97J-5u02A:
undetectable		 4a97J-5u02A:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 5u02 GLYCOSYL TRANSFERASE
(Staphylococcus
aureus) 		4 / 6 GLN A 283
GLU A 287
HIS A 302
ALA A 306
 None
 1.38A 6f6jC-5u02A:
undetectable
6f6jD-5u02A:
undetectable		 6f6jC-5u02A:
21.58
6f6jD-5u02A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLO_A_GBQA1501_1
(SUBSTANCE-P
RECEPTOR,GLGA
GLYCOGEN
SYNTHASE,SUBSTANCE-P
RECEPTOR)		 5u02 GLYCOSYL TRANSFERASE
(Staphylococcus
aureus) 		5 / 9 ASN A 413
GLU A 434
VAL A 446
ILE A 483
MET A 415
 None
 1.49A 6hloA-5u02A:
undetectable		 6hloA-5u02A:
19.92