SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u08'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 5u08 AAC3-I
(uncultured
bacterium) 		4 / 5 LEU A  30
LEU A  27
SER A  74
GLY A  71
 None
 0.82A 1a4lC-5u08A:
undetectable		 1a4lC-5u08A:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5u08 AAC3-I
(uncultured
bacterium) 		3 / 3 LEU A  48
ILE A  25
ARG A  29
 None
 0.67A 4mk4B-5u08A:
undetectable		 4mk4B-5u08A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 5u08 AAC3-I
(uncultured
bacterium) 		5 / 10 GLY A  70
GLY A  71
ILE A 103
ALA A  93
GLY A 104
 None
None
ACT  A 203 ( 4.8A)
None
ACT  A 203 (-3.7A)
 1.01A 6e5zA-5u08A:
undetectable		 6e5zA-5u08A:
22.22