SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u0r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_A_RBFA296_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 5u0r DH270.UCA1 LIGHT
CHAIN
(Homo
sapiens) 		5 / 11 THR L 166
VAL L 199
VAL L 148
LYS L 208
LEU L 139
 None
 1.49A 1t6zA-5u0rL:
undetectable		 1t6zA-5u0rL:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 5u0r DH270.UCA1 LIGHT
CHAIN
(Homo
sapiens) 		5 / 10 SER L  31
LEU L 100
SER L  92
ILE L  98
GLY L  95
 None
 1.41A 3ik6B-5u0rL:
undetectable
3ik6E-5u0rL:
undetectable		 3ik6B-5u0rL:
21.37
3ik6E-5u0rL:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)		 5u0r DH270.UCA1 LIGHT
CHAIN
(Homo
sapiens) 		5 / 9 LEU L 107
THR L 105
VAL L  10
ILE L  18
PHE L  64
 None
 1.03A 3tbgD-5u0rL:
undetectable		 3tbgD-5u0rL:
16.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ACL_A_SASA1111_1
(MCG)		 5u0r DH270.UCA1 LIGHT
CHAIN
(Homo
sapiens) 		5 / 7 SER L  36
TYR L  38
TYR L  51
GLU L  52
PRO L  57
 None
 0.35A 5aclA-5u0rL:
22.0		 5aclA-5u0rL:
80.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 5u0r DH270.UCA1 LIGHT
CHAIN
(Homo
sapiens) 		4 / 8 SER L  36
TYR L  38
SER L  97
PHE L 101
 None
 0.76A 5alcL-5u0rL:
17.9		 5alcL-5u0rL:
82.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 5u0r DH270.UCA1 LIGHT
CHAIN
(Homo
sapiens) 		5 / 12 ARG L  56
ASN L  62
SER L  17
GLN L  39
GLY L  15
 None
 1.31A 5oj0A-5u0rL:
undetectable		 5oj0A-5u0rL:
15.87