SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u1a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5u1a FERRITIN,MTRE
PROTEIN CHIMERA
(Helicobacter
pylori;
Neisseria
gonorrhoeae) 		5 / 12 PHE A  95
GLY A  97
LEU A  23
LEU A  58
TYR A  24
 None
 0.97A 1fm6X-5u1aA:
undetectable		 1fm6X-5u1aA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5u1a FERRITIN,MTRE
PROTEIN CHIMERA
(Helicobacter
pylori;
Neisseria
gonorrhoeae) 		3 / 3 LYS A 181
ASP A 170
CYH A  31
 None
 1.50A 2br4F-5u1aA:
undetectable		 2br4F-5u1aA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U52_A_CUA515_0
(PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN)		 5u1a FERRITIN,MTRE
PROTEIN CHIMERA
(Helicobacter
pylori;
Neisseria
gonorrhoeae) 		3 / 3 HIS A 111
HIS A 108
ILE A 112
 None
 0.84A 3u52A-5u1aA:
1.0
3u52C-5u1aA:
10.1		 3u52A-5u1aA:
17.30
3u52C-5u1aA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5u1a FERRITIN,MTRE
PROTEIN CHIMERA
(Helicobacter
pylori;
Neisseria
gonorrhoeae) 		5 / 12 SER A 115
ILE A 116
TYR A 138
LEU A 135
LEU A  76
 None
 1.12A 3vn2A-5u1aA:
undetectable		 3vn2A-5u1aA:
21.18