SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u1b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5u1b MTRE
PROTEIN,FERRITIN
CHIMERA
(Helicobacter
pylori;
Neisseria
gonorrhoeae) 		5 / 12 ILE A 101
LEU A  57
ALA A 108
ILE A   6
ILE A   7
 None
 0.93A 1epbA-5u1bA:
undetectable		 1epbA-5u1bA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5u1b MTRE
PROTEIN,FERRITIN
CHIMERA
(Helicobacter
pylori;
Neisseria
gonorrhoeae) 		5 / 12 ILE A 101
LEU A  57
ALA A 108
ILE A   6
ILE A   7
 None
 0.93A 1epbB-5u1bA:
undetectable		 1epbB-5u1bA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZQ_A_PCFA954_0
(CATECHOL
1,2-DIOXYGENASE)		 5u1b MTRE
PROTEIN,FERRITIN
CHIMERA
(Helicobacter
pylori;
Neisseria
gonorrhoeae) 		5 / 9 LEU A  83
HIS A  93
ALA A  90
TYR A  91
GLU A 131
 None
 1.46A 2azqA-5u1bA:
0.5		 2azqA-5u1bA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 5u1b MTRE
PROTEIN,FERRITIN
CHIMERA
(Helicobacter
pylori;
Neisseria
gonorrhoeae) 		4 / 8 ILE A  86
ALA A  90
PHE A 134
LEU A  23
 None
 0.95A 3hrdA-5u1bA:
undetectable
3hrdB-5u1bA:
undetectable		 3hrdA-5u1bA:
18.41
3hrdB-5u1bA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 5u1b MTRE
PROTEIN,FERRITIN
CHIMERA
(Helicobacter
pylori;
Neisseria
gonorrhoeae) 		5 / 9 GLY A 150
ASP A 155
LEU A 151
ASN A 146
ILE A 141
 None
 1.46A 3wdmA-5u1bA:
undetectable		 3wdmA-5u1bA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5u1b MTRE
PROTEIN,FERRITIN
CHIMERA
(Helicobacter
pylori;
Neisseria
gonorrhoeae) 		4 / 7 TYR A 123
GLU A  49
GLU A  17
GLU A  94
 None
 1.26A 4mi4A-5u1bA:
undetectable
4mi4C-5u1bA:
undetectable		 4mi4A-5u1bA:
27.15
4mi4C-5u1bA:
27.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_E_377E401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5u1b MTRE
PROTEIN,FERRITIN
CHIMERA
(Helicobacter
pylori;
Neisseria
gonorrhoeae) 		4 / 6 ASN A 102
GLU A  17
TYR A 123
LEU A 120
 None
 1.30A 4twdD-5u1bA:
3.8
4twdE-5u1bA:
3.8		 4twdD-5u1bA:
19.75
4twdE-5u1bA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		 5u1b MTRE
PROTEIN,FERRITIN
CHIMERA
(Helicobacter
pylori;
Neisseria
gonorrhoeae) 		3 / 3 VAL A 124
GLU A  50
GLU A  17
 None
 0.91A 5jsdB-5u1bA:
undetectable
5jsdC-5u1bA:
undetectable		 5jsdB-5u1bA:
14.05
5jsdC-5u1bA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5u1b MTRE
PROTEIN,FERRITIN
CHIMERA
(Helicobacter
pylori;
Neisseria
gonorrhoeae) 		4 / 4 GLN A  69
THR A  71
GLU A  12
LEU A  57
 None
 1.40A 5m66A-5u1bA:
undetectable		 5m66A-5u1bA:
18.05