SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u1h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_A_STIA201_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 5u1h OUTER MEMBRANE PORIN
F
(Pseudomonas
aeruginosa) 		4 / 6 VAL A 111
VAL A  85
ILE A  29
ARG A  65
 None
 0.85A 1iepA-5u1hA:
undetectable		 1iepA-5u1hA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5u1h OUTER MEMBRANE PORIN
F
(Pseudomonas
aeruginosa) 		4 / 6 VAL A 111
VAL A  85
ILE A  29
ARG A  65
 None
 1.14A 3ms9A-5u1hA:
undetectable		 3ms9A-5u1hA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5u1h OUTER MEMBRANE PORIN
F
(Pseudomonas
aeruginosa) 		4 / 6 VAL A 111
VAL A  85
ILE A  29
ARG A  65
 None
 1.13A 3mssA-5u1hA:
undetectable		 3mssA-5u1hA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5u1h OUTER MEMBRANE PORIN
F
(Pseudomonas
aeruginosa) 		4 / 7 VAL A 111
VAL A  85
ILE A  29
ARG A  65
 None
 0.80A 3mssB-5u1hA:
undetectable		 3mssB-5u1hA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5u1h OUTER MEMBRANE PORIN
F
(Pseudomonas
aeruginosa) 		4 / 6 VAL A 111
VAL A  85
ILE A  29
ARG A  65
 None
 1.13A 3mssC-5u1hA:
undetectable		 3mssC-5u1hA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_A_ACTA603_0
(CHOLINE OXIDASE)		 5u1h OUTER MEMBRANE PORIN
F
(Pseudomonas
aeruginosa) 		3 / 3 ARG A  94
HIS A  49
SER A  93
 None
 0.88A 4mjwA-5u1hA:
undetectable
4mjwB-5u1hA:
undetectable		 4mjwA-5u1hA:
12.64
4mjwB-5u1hA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 5u1h OUTER MEMBRANE PORIN
F
(Pseudomonas
aeruginosa) 		3 / 3 SER A  93
ARG A  94
HIS A  49
 None
 0.86A 4mjwA-5u1hA:
undetectable
4mjwB-5u1hA:
undetectable		 4mjwA-5u1hA:
12.64
4mjwB-5u1hA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 5u1h OUTER MEMBRANE PORIN
F
(Pseudomonas
aeruginosa) 		4 / 7 ALA A  67
ARG A  84
GLY A  82
GLU A  81
 None
 0.89A 5bs8A-5u1hA:
undetectable
5bs8B-5u1hA:
2.9
5bs8C-5u1hA:
undetectable		 5bs8A-5u1hA:
15.37
5bs8B-5u1hA:
20.70
5bs8C-5u1hA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 5u1h OUTER MEMBRANE PORIN
F
(Pseudomonas
aeruginosa) 		4 / 7 ALA A  67
ARG A  84
GLY A  82
GLU A  81
 None
 0.91A 5btdA-5u1hA:
undetectable
5btdB-5u1hA:
2.8
5btdC-5u1hA:
undetectable		 5btdA-5u1hA:
15.37
5btdB-5u1hA:
20.70
5btdC-5u1hA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5u1h OUTER MEMBRANE PORIN
F
(Pseudomonas
aeruginosa) 		4 / 7 ALA A  67
ARG A  84
GLY A  82
GLU A  81
 None
 0.91A 5btdA-5u1hA:
undetectable
5btdC-5u1hA:
undetectable
5btdD-5u1hA:
undetectable		 5btdA-5u1hA:
15.37
5btdC-5u1hA:
15.37
5btdD-5u1hA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 5u1h OUTER MEMBRANE PORIN
F
(Pseudomonas
aeruginosa) 		4 / 6 ALA A  67
ARG A  84
GLY A  82
GLU A  81
 None
 0.93A 5btgA-5u1hA:
undetectable
5btgB-5u1hA:
2.8
5btgC-5u1hA:
undetectable		 5btgA-5u1hA:
15.37
5btgB-5u1hA:
20.70
5btgC-5u1hA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 5u1h OUTER MEMBRANE PORIN
F
(Pseudomonas
aeruginosa) 		3 / 3 THR A  55
ASP A  56
ALA A  57
 None
 0.04A 5g5gB-5u1hA:
undetectable		 5g5gB-5u1hA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 5u1h OUTER MEMBRANE PORIN
F
(Pseudomonas
aeruginosa) 		4 / 6 PHE A  16
ARG A 109
ASN A  99
ASP A  51
 7QA  A 201 (-4.4A)
None
None
7QA  A 201 (-3.4A)
 1.29A 6dhbA-5u1hA:
undetectable		 6dhbA-5u1hA:
18.11