SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u24'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 GLY A  48
CYH A  47
HIS A 130
LEU A 241
LEU A 172
 EDO  A 403 ( 4.5A)
None
None
None
None
 1.42A 1fm6D-5u24A:
undetectable		 1fm6D-5u24A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAB_F_RTLF2_0
(PROTEIN (RETINOL
BINDING PROTEIN))		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 PHE A  39
ALA A 192
LEU A  32
GLY A  58
HIS A 160
 None
None
None
7SG  A 402 (-3.5A)
None
 1.17A 1qabF-5u24A:
undetectable		 1qabF-5u24A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 LEU A 237
ILE A  53
GLY A  54
VAL A  55
LEU A  64
 None
 0.96A 1vptA-5u24A:
undetectable		 1vptA-5u24A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 GLY A  48
CYH A  47
HIS A 130
LEU A 241
LEU A 172
 EDO  A 403 ( 4.5A)
None
None
None
None
 1.44A 1zgyA-5u24A:
undetectable		 1zgyA-5u24A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 LEU A  62
GLY A 193
SER A 227
ASN A  57
ALA A 184
 None
None
None
7SG  A 402 (-4.0A)
None
 0.97A 2bm9B-5u24A:
2.3		 2bm9B-5u24A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		4 / 6 ASN A 185
HIS A 279
ASN A 248
ILE A 163
 None
 1.19A 2hkkA-5u24A:
undetectable		 2hkkA-5u24A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_B_VDYB6178_1
(VITAMIN D
HYDROXYLASE)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 ILE A  85
THR A  83
VAL A  79
PRO A  98
LEU A 100
 None
 1.41A 3a51B-5u24A:
undetectable		 3a51B-5u24A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APX_A_Z80A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 PHE A  39
PHE A  43
LEU A 244
ALA A 184
PHE A 180
 None
 1.48A 3apxA-5u24A:
undetectable		 3apxA-5u24A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 LEU A 209
VAL A  55
GLY A  54
LEU A 229
ILE A 153
 None
 1.09A 3ijdA-5u24A:
undetectable		 3ijdA-5u24A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		4 / 5 PHE A  43
GLY A 177
CYH A 156
HIS A 160
 None
 1.33A 3r0lD-5u24A:
undetectable		 3r0lD-5u24A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 11 TYR A 132
GLY A 133
GLY A 161
PHE A 178
ALA A 176
 None
 1.15A 3sufC-5u24A:
undetectable		 3sufC-5u24A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		4 / 4 ASN A 248
GLY A 161
ASP A 104
ASP A 275
 None
 1.13A 4n49A-5u24A:
undetectable		 4n49A-5u24A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA205_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 GLU A  40
CYH A 194
ARG A 207
ALA A 210
LEU A 209
 None
 1.45A 4oadA-5u24A:
undetectable		 4oadA-5u24A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 ASP A 155
LEU A  59
GLY A  58
 7SG  A 402 (-2.6A)
7SG  A 402 (-4.4A)
7SG  A 402 (-3.5A)
 0.48A 4xmfA-5u24A:
undetectable		 4xmfA-5u24A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_B_FOLB201_0
(FOLATE ECF
TRANSPORTER)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 TYR A 258
PHE A 348
THR A 342
ARG A  12
LYS A 240
 None
 1.47A 4z7fB-5u24A:
undetectable		 4z7fB-5u24A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 GLY A  58
ILE A 195
LEU A  64
GLY A  54
GLY A 187
 7SG  A 402 (-3.5A)
None
None
None
None
 1.00A 5d4uA-5u24A:
3.3		 5d4uA-5u24A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 GLY A  58
ILE A 195
LEU A  64
GLY A  54
GLY A 187
 7SG  A 402 (-3.5A)
None
None
None
None
 1.07A 5d4uB-5u24A:
2.9		 5d4uB-5u24A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 GLY A  58
ILE A 195
LEU A  64
GLY A  54
GLY A 187
 7SG  A 402 (-3.5A)
None
None
None
None
 1.02A 5d4uD-5u24A:
undetectable		 5d4uD-5u24A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWZ_D_010D6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
PEDV MAIN PROTEASE)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 MET A 138
HIS A 130
GLY A 173
 None
 0.85A 5gwzB-5u24A:
undetectable		 5gwzB-5u24A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_E_SC2E1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 VAL A 169
GLN A 158
CYH A 156
 None
7SG  A 402 (-3.7A)
None
 0.84A 5icxA-5u24A:
undetectable
5icxE-5u24A:
undetectable		 5icxA-5u24A:
20.48
5icxE-5u24A:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 THR A  83
ILE A  85
LEU A  89
LEU A  62
ALA A  86
 None
None
None
None
7SG  A 402 ( 3.7A)
 0.98A 5l0zA-5u24A:
undetectable		 5l0zA-5u24A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 10 THR A  83
ILE A  85
LEU A  89
LEU A  62
ALA A  86
 None
None
None
None
7SG  A 402 ( 3.7A)
 1.03A 5l0zB-5u24A:
undetectable		 5l0zB-5u24A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 HIS A 279
ALA A 184
SER A 179
THR A 342
LEU A   6
 None
None
7SG  A 402 (-2.7A)
None
7SG  A 402 (-4.0A)
 1.45A 5m54B-5u24A:
undetectable		 5m54B-5u24A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_1
(CYTOCHROME P450 2C9)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 PHE A  39
ASN A 185
LEU A 244
GLY A 187
ALA A 188
 None
 1.46A 5x23A-5u24A:
undetectable		 5x23A-5u24A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_1
(CYTOCHROME P450 2C9)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 VAL A 169
ASN A 272
GLY A 133
ALA A 159
LEU A 244
 None
 0.99A 5x23A-5u24A:
undetectable		 5x23A-5u24A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_1
(CYTOCHROME P450 2C9)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 VAL A 169
ASN A 272
GLY A 133
ALA A 159
LEU A 244
 None
 1.03A 5xxiA-5u24A:
undetectable		 5xxiA-5u24A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GH9_A_MIXA1003_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		4 / 5 ASN A  94
TYR A 222
GLY A 213
ASP A  70
 None
 0.77A 6gh9A-5u24A:
undetectable		 6gh9A-5u24A:
12.16