SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u2l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5u2l HEAT SHOCK PROTEIN
104
(Candida
albicans) 		5 / 12 ALA A  34
ALA A  35
ASN A  13
LEU A  71
ILE A  84
 None
 0.95A 2aclA-5u2lA:
undetectable
2aclE-5u2lA:
undetectable		 2aclA-5u2lA:
19.92
2aclE-5u2lA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 5u2l HEAT SHOCK PROTEIN
104
(Candida
albicans) 		5 / 12 VAL A  93
PHE A 128
PHE A  63
HIS A  31
ALA A  35
 None
 1.14A 3apvA-5u2lA:
undetectable		 3apvA-5u2lA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 5u2l HEAT SHOCK PROTEIN
104
(Candida
albicans) 		5 / 12 VAL A  93
PHE A 128
PHE A  63
HIS A  31
ALA A  35
 None
 1.17A 3apvB-5u2lA:
undetectable		 3apvB-5u2lA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CD2_A_MTXA307_1
(DIHYDROFOLATE
REDUCTASE)		 5u2l HEAT SHOCK PROTEIN
104
(Candida
albicans) 		5 / 12 ILE A  66
LEU A  49
ILE A  37
LEU A  30
ILE A 127
 None
 1.17A 3cd2A-5u2lA:
undetectable		 3cd2A-5u2lA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 5u2l HEAT SHOCK PROTEIN
104
(Candida
albicans) 		5 / 12 LEU A  33
ALA A  35
LEU A  49
ILE A 127
LEU A  71
 None
 1.24A 3olsB-5u2lA:
undetectable		 3olsB-5u2lA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)		 5u2l HEAT SHOCK PROTEIN
104
(Candida
albicans) 		5 / 9 PHE A 128
LEU A  49
THR A  51
LEU A 119
ILE A 138
 None
 1.19A 3tbgD-5u2lA:
undetectable		 3tbgD-5u2lA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3A_A_TACA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 5u2l HEAT SHOCK PROTEIN
104
(Candida
albicans) 		5 / 12 SER A 158
PRO A  38
GLN A  47
GLN A 111
ILE A  11
 None
 1.43A 4b3aA-5u2lA:
undetectable		 4b3aA-5u2lA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 5u2l HEAT SHOCK PROTEIN
104
(Candida
albicans) 		4 / 7 GLN A 122
ASP A 126
HIS A  70
TYR A  58
 None
 1.24A 5ov9B-5u2lA:
undetectable		 5ov9B-5u2lA:
13.67