SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u2w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_1
(PROTEIN (HIV-1
PROTEASE))		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 10 ALA A 170
ASP A 172
GLY A 164
ILE A 163
VAL A 137
 None
 1.07A 1d4yA-5u2wA:
undetectable		 1d4yA-5u2wA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_2
(HIV-1 PROTEASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 9 ALA A 170
ASP A 172
GLY A 164
ILE A 163
VAL A 137
 None
 0.90A 1hpvB-5u2wA:
undetectable		 1hpvB-5u2wA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		6 / 12 TYR A 155
ILE A  18
GLY A 140
ALA A 160
SER A 158
GLY A 186
 IMD  A 304 ( 4.3A)
NAP  A 301 (-4.0A)
None
None
None
NAP  A 301 (-4.7A)
 1.19A 1kiaA-5u2wA:
7.4		 1kiaA-5u2wA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 TYR A 155
ILE A  18
GLY A 140
ALA A 160
GLY A 186
 IMD  A 304 ( 4.3A)
NAP  A 301 (-4.0A)
None
None
NAP  A 301 (-4.7A)
 1.08A 1kiaB-5u2wA:
5.8		 1kiaB-5u2wA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 TYR A 155
ILE A  18
GLY A 140
ALA A 160
GLY A 186
 IMD  A 304 ( 4.3A)
NAP  A 301 (-4.0A)
None
None
NAP  A 301 (-4.7A)
 1.08A 1kiaC-5u2wA:
7.3		 1kiaC-5u2wA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		3 / 3 ARG A 135
ARG A   8
ARG A 231
 None
 1.10A 1l7fA-5u2wA:
undetectable		 1l7fA-5u2wA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		3 / 3 ARG A 135
ARG A   8
ARG A 231
 None
 1.10A 1l7hA-5u2wA:
undetectable		 1l7hA-5u2wA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 TYR A 155
ILE A  18
GLY A 140
ALA A 160
SER A 158
 IMD  A 304 ( 4.3A)
NAP  A 301 (-4.0A)
None
None
None
 1.20A 1nbhA-5u2wA:
6.8		 1nbhA-5u2wA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		6 / 12 TYR A 155
ILE A  18
GLY A 140
ALA A 160
SER A 158
GLY A 186
 IMD  A 304 ( 4.3A)
NAP  A 301 (-4.0A)
None
None
None
NAP  A 301 (-4.7A)
 1.22A 1nbhB-5u2wA:
6.5		 1nbhB-5u2wA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 TYR A 155
ILE A  18
GLY A 140
ALA A 160
SER A 158
 IMD  A 304 ( 4.3A)
NAP  A 301 (-4.0A)
None
None
None
 1.21A 1nbhC-5u2wA:
5.9		 1nbhC-5u2wA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 TYR A 155
ILE A  18
GLY A 140
ALA A 160
SER A 158
 IMD  A 304 ( 4.3A)
NAP  A 301 (-4.0A)
None
None
None
 1.21A 1nbhD-5u2wA:
5.9		 1nbhD-5u2wA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		6 / 12 TYR A 155
ILE A  18
GLY A 140
ALA A 160
SER A 158
GLY A 186
 IMD  A 304 ( 4.3A)
NAP  A 301 (-4.0A)
None
None
None
NAP  A 301 (-4.7A)
 1.23A 1nbiA-5u2wA:
6.4		 1nbiA-5u2wA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		6 / 12 TYR A 155
ILE A  18
GLY A 140
ALA A 160
SER A 158
GLY A 186
 IMD  A 304 ( 4.3A)
NAP  A 301 (-4.0A)
None
None
None
NAP  A 301 (-4.7A)
 1.22A 1nbiB-5u2wA:
7.1		 1nbiB-5u2wA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		6 / 12 TYR A 155
GLY A 140
THR A 139
ALA A 160
SER A 158
GLY A 186
 IMD  A 304 ( 4.3A)
None
NAP  A 301 ( 3.8A)
None
None
NAP  A 301 (-4.7A)
 1.29A 1nbiC-5u2wA:
5.5		 1nbiC-5u2wA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		6 / 12 TYR A 155
GLY A 140
THR A 139
ALA A 160
SER A 158
GLY A 186
 IMD  A 304 ( 4.3A)
None
NAP  A 301 ( 3.8A)
None
None
NAP  A 301 (-4.7A)
 1.28A 1nbiD-5u2wA:
5.5		 1nbiD-5u2wA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ALA A 170
ASP A 172
GLY A 164
ILE A 163
VAL A 137
 None
 0.95A 2f81B-5u2wA:
undetectable		 2f81B-5u2wA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_1
(CYTOCHROME P450 2C8)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 THR A 190
VAL A 218
ALA A 219
VAL A  11
VAL A 137
 NAP  A 301 (-2.8A)
None
None
None
None
 0.74A 2nniA-5u2wA:
undetectable		 2nniA-5u2wA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNJ_A_225A501_1
(CYTOCHROME P450 2C8)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 10 VAL A 218
ALA A 219
VAL A 226
VAL A  89
VAL A 225
 None
 1.07A 2nnjA-5u2wA:
undetectable		 2nnjA-5u2wA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_1
(PROTEASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 11 ALA A 170
ASP A 172
GLY A 164
ILE A 163
VAL A 137
 None
 1.04A 2o4pA-5u2wA:
undetectable		 2o4pA-5u2wA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_1
(PROTEASE RETROPEPSIN)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 11 ALA A 170
ASP A 172
GLY A 164
ILE A 163
VAL A 137
 None
 1.02A 2qhcA-5u2wA:
undetectable		 2qhcA-5u2wA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ALA A 170
ASP A 172
GLY A 164
ILE A 163
VAL A 137
 None
 1.07A 2qhcB-5u2wA:
undetectable		 2qhcB-5u2wA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_2
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 4 VAL A  89
ARG A  25
ILE A  51
THR A 139
 None
None
None
NAP  A 301 ( 3.8A)
 1.19A 3cl9A-5u2wA:
1.8		 3cl9A-5u2wA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_2
(HIV-1 PROTEASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ALA A 170
ASP A 172
GLY A 164
ILE A 163
VAL A 137
 None
 0.96A 3d1xB-5u2wA:
undetectable		 3d1xB-5u2wA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ALA A 170
ASP A 172
GLY A 164
ILE A 163
VAL A 137
 None
 0.95A 3lzsA-5u2wA:
undetectable		 3lzsA-5u2wA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ALA A 170
ASP A 172
GLY A 164
ILE A 163
VAL A 137
 None
 0.96A 3lzsB-5u2wA:
undetectable		 3lzsB-5u2wA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ALA A 170
ASP A 172
GLY A 164
ILE A 163
VAL A 137
 None
 0.97A 3lzuA-5u2wA:
undetectable		 3lzuA-5u2wA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 11 ALA A  58
VAL A  47
ILE A  35
ILE A  87
ILE A  51
 None
 0.93A 3lzvB-5u2wA:
undetectable		 3lzvB-5u2wA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 10 VAL A  89
ALA A 215
THR A 188
ILE A 240
VAL A 183
 None
None
NAP  A 301 (-4.4A)
None
None
 1.02A 3me6A-5u2wA:
undetectable		 3me6A-5u2wA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_2
(HIV-1 PROTEASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ALA A 170
ASP A 172
GLY A 164
ILE A 163
VAL A 137
 None
 0.97A 3mwsB-5u2wA:
undetectable		 3mwsB-5u2wA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_1
(PROTEASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 10 ALA A  58
VAL A  47
ILE A  35
ILE A  87
ILE A  51
 None
 0.98A 3nujA-5u2wA:
undetectable		 3nujA-5u2wA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_1
(PROTEASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ALA A 170
ASP A 172
GLY A 164
ILE A 163
VAL A 137
 None
 0.93A 3pwmA-5u2wA:
undetectable		 3pwmA-5u2wA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 5 SER A 141
ILE A  18
TYR A 155
GLY A 186
 IMD  A 304 (-3.4A)
NAP  A 301 (-4.0A)
IMD  A 304 ( 4.3A)
NAP  A 301 (-4.7A)
 1.01A 3uboB-5u2wA:
7.6		 3uboB-5u2wA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 7 ALA A 161
ILE A 163
HIS A 184
GLY A 140
 None
 1.00A 3v4tH-5u2wA:
undetectable		 3v4tH-5u2wA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 10 ALA A 170
ASP A 172
GLY A 164
ILE A 163
VAL A 137
 None
 1.06A 4dqcA-5u2wA:
undetectable		 4dqcA-5u2wA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ALA A 200
ARG A 204
ALA A 215
GLY A 213
TYR A 212
 None
 1.25A 4r29B-5u2wA:
undetectable		 4r29B-5u2wA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ALA A 200
ARG A 204
ALA A 215
GLY A 213
TYR A 212
 None
 1.28A 4r29C-5u2wA:
undetectable		 4r29C-5u2wA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ILE A  35
ALA A 219
ARG A  43
VAL A  47
ILE A  51
 None
 1.10A 4rvdA-5u2wA:
5.7		 4rvdA-5u2wA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ILE A  35
ALA A 219
ARG A  43
VAL A  47
ILE A  51
 None
 1.12A 4rvgA-5u2wA:
5.8		 4rvgA-5u2wA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 11 ALA A  58
VAL A  47
ILE A  35
ILE A  87
ILE A  51
 None
 0.96A 4rvjA-5u2wA:
undetectable		 4rvjA-5u2wA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 11 ALA A  58
VAL A  47
ILE A  35
ILE A  87
ILE A  51
 None
 0.95A 4rvjC-5u2wA:
undetectable		 4rvjC-5u2wA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 4 ALA A 122
VAL A  89
GLY A  13
THR A  36
 None
None
NAP  A 301 (-3.4A)
None
 1.16A 4ubeA-5u2wA:
7.3		 4ubeA-5u2wA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		3 / 3 ASN A 193
SER A 187
ARG A 206
 NAP  A 301 ( 3.8A)
None
None
 0.81A 5b2qA-5u2wA:
undetectable		 5b2qA-5u2wA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB203_0
(HYDROXYNITRILE LYASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 4 VAL A  78
ALA A  74
ILE A  35
THR A  36
 None
 1.11A 5e4dB-5u2wA:
undetectable		 5e4dB-5u2wA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_2
(PROTEASE E35D-APV)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 9 ALA A 170
ASP A 172
GLY A 164
ILE A 163
VAL A 137
 None
 1.05A 5kr0B-5u2wA:
undetectable		 5kr0B-5u2wA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ILE A 240
VAL A 183
THR A 139
ILE A  22
ALA A  21
 None
None
NAP  A 301 ( 3.8A)
None
None
 1.06A 5lg3E-5u2wA:
undetectable		 5lg3E-5u2wA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		3 / 3 ALA A  74
GLN A  62
THR A  36
 None
 0.75A 5n0oA-5u2wA:
2.1		 5n0oA-5u2wA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 5 GLN A 203
THR A 239
HIS A 184
LEU A 143
 IMD  A 304 ( 4.4A)
None
None
IMD  A 304 (-4.7A)
 1.44A 6aphA-5u2wA:
9.0		 6aphA-5u2wA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)		 5u2w SHORT CHAIN
DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 5 GLN A 203
THR A 239
HIS A 184
LEU A 143
 IMD  A 304 ( 4.4A)
None
None
IMD  A 304 (-4.7A)
 1.41A 6gbnB-5u2wA:
3.1		 6gbnB-5u2wA:
22.00