SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u32'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 5u32 TRNA LIGASE
(Candida
albicans) 		3 / 3 ARG A 494
THR A 410
VAL A 502
 None
 0.87A 1hxbA-5u32A:
undetectable		 1hxbA-5u32A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 5u32 TRNA LIGASE
(Candida
albicans) 		3 / 3 ARG A 494
THR A 410
VAL A 502
 None
 0.80A 2qakA-5u32A:
undetectable		 2qakA-5u32A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 5u32 TRNA LIGASE
(Candida
albicans) 		4 / 9 ILE A 486
ARG A 483
ALA A 508
VAL A 416
 None
 0.99A 2vufB-5u32A:
undetectable		 2vufB-5u32A:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5u32 TRNA LIGASE
(Candida
albicans) 		4 / 6 ARG A 595
ILE A 596
ILE A 618
ASP A 615
 None
 1.11A 4w5qA-5u32A:
3.7		 4w5qA-5u32A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5u32 TRNA LIGASE
(Candida
albicans) 		4 / 6 ARG A 595
ILE A 596
ILE A 618
ASP A 615
 None
 1.14A 4w5tA-5u32A:
3.4		 4w5tA-5u32A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 5u32 TRNA LIGASE
(Candida
albicans) 		4 / 6 ARG A 595
ILE A 596
ILE A 618
ASP A 615
 None
 1.12A 4z4cA-5u32A:
3.8		 4z4cA-5u32A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5u32 TRNA LIGASE
(Candida
albicans) 		4 / 6 ARG A 595
ILE A 596
ILE A 618
ASP A 615
 None
 1.15A 4z4dA-5u32A:
3.8		 4z4dA-5u32A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5u32 TRNA LIGASE
(Candida
albicans) 		4 / 5 ALA A 479
TYR A 559
HIS A 574
PRO A 417
 None
 1.22A 4ze2A-5u32A:
undetectable		 4ze2A-5u32A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 5u32 TRNA LIGASE
(Candida
albicans) 		5 / 9 LEU A 463
VAL A 471
ILE A 486
PHE A 473
ILE A 490
 None
 1.24A 5yf9X-5u32A:
undetectable		 5yf9X-5u32A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)		 5u32 TRNA LIGASE
(Candida
albicans) 		4 / 6 ARG A 595
ILE A 596
ILE A 618
ASP A 615
 None
 1.10A 6cbdA-5u32A:
2.0		 6cbdA-5u32A:
13.04