SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u38'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5u38 LECTIN
(Platypodium
elegans) 		4 / 5 PHE A  91
PHE A 216
LEU A 229
PHE A  11
 None
 1.38A 2y69C-5u38A:
undetectable
2y69J-5u38A:
undetectable		 2y69C-5u38A:
23.69
2y69J-5u38A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5u38 LECTIN
(Platypodium
elegans) 		4 / 5 PHE A  91
PHE A 216
LEU A 229
PHE A  11
 None
 1.35A 3abmC-5u38A:
undetectable
3abmJ-5u38A:
undetectable		 3abmC-5u38A:
23.69
3abmJ-5u38A:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5u38 LECTIN
(Platypodium
elegans) 		4 / 5 PHE A  91
PHE A 216
LEU A 229
PHE A  11
 None
 1.34A 3ag3C-5u38A:
undetectable
3ag3J-5u38A:
undetectable		 3ag3C-5u38A:
23.69
3ag3J-5u38A:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_B_SAMB770_0
(23S RRNA
METHYLTRANSFERASE)		 5u38 LECTIN
(Platypodium
elegans) 		6 / 12 LEU A 109
GLY A 106
GLY A 221
ILE A  89
LEU A  34
VAL A  48
 None
MDM  A 304 ( 3.8A)
MDM  A 304 (-3.2A)
None
None
None
 1.44A 3nk7B-5u38A:
undetectable		 3nk7B-5u38A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP6_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 5u38 LECTIN
(Platypodium
elegans) 		5 / 12 PHE A 234
THR A 176
VAL A 186
ILE A  93
VAL A  57
 None
 1.40A 3sp6A-5u38A:
undetectable		 3sp6A-5u38A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5u38 LECTIN
(Platypodium
elegans) 		3 / 3 THR A 170
ASN A 172
GLU A 230
 None
 0.59A 3v4tA-5u38A:
undetectable
3v4tC-5u38A:
undetectable		 3v4tA-5u38A:
18.36
3v4tC-5u38A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 5u38 LECTIN
(Platypodium
elegans) 		4 / 8 SER A   7
LEU A 174
SER A 233
THR A 235
 None
 0.58A 4iklA-5u38A:
undetectable
4iklB-5u38A:
undetectable		 4iklA-5u38A:
23.83
4iklB-5u38A:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWL_A_ASCA303_0
(DIOSCORIN 5)		 5u38 LECTIN
(Platypodium
elegans) 		5 / 10 ASP A 151
VAL A 186
VAL A 175
PHE A 130
ALA A  90
 None
 1.26A 4twlA-5u38A:
undetectable		 4twlA-5u38A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWL_B_ASCB304_0
(DIOSCORIN 5)		 5u38 LECTIN
(Platypodium
elegans) 		5 / 10 ASP A 151
VAL A 186
VAL A 175
PHE A 130
ALA A  90
 None
 1.29A 4twlB-5u38A:
undetectable		 4twlB-5u38A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 5u38 LECTIN
(Platypodium
elegans) 		3 / 3 THR A 116
ALA A 122
ASN A 119
 None
NAG  A 301 (-3.5A)
NAG  A 301 (-1.8A)
 0.60A 5ersA-5u38A:
undetectable		 5ersA-5u38A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5u38 LECTIN
(Platypodium
elegans) 		4 / 8 THR A  26
LEU A  32
ILE A  51
LEU A 229
 None
 0.96A 5g48A-5u38A:
undetectable		 5g48A-5u38A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5u38 LECTIN
(Platypodium
elegans) 		4 / 8 THR A 183
TYR A 177
THR A 176
GLN A  71
 None
 1.35A 5tzoA-5u38A:
undetectable		 5tzoA-5u38A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5u38 LECTIN
(Platypodium
elegans) 		4 / 8 THR A 183
TYR A 177
THR A 176
GLN A  71
 None
 1.39A 5tzoB-5u38A:
5.1		 5tzoB-5u38A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5u38 LECTIN
(Platypodium
elegans) 		4 / 8 THR A 183
TYR A 177
THR A 176
GLN A  71
 None
 1.37A 5tzoC-5u38A:
undetectable		 5tzoC-5u38A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5u38 LECTIN
(Platypodium
elegans) 		4 / 5 PHE A  91
PHE A 216
LEU A 229
PHE A  11
 None
 1.34A 5wauC-5u38A:
undetectable
5wauJ-5u38A:
undetectable		 5wauC-5u38A:
23.69
5wauJ-5u38A:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5u38 LECTIN
(Platypodium
elegans) 		4 / 5 PHE A  91
PHE A 216
LEU A 229
PHE A  11
 None
 1.34A 5wauc-5u38A:
undetectable
5wauj-5u38A:
undetectable		 5wauc-5u38A:
23.69
5wauj-5u38A:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_0
(CARNOSINE
N-METHYLTRANSFERASE)		 5u38 LECTIN
(Platypodium
elegans) 		5 / 12 GLY A 110
GLY A  49
SER A 220
PHE A 112
PHE A 216
 None
 1.35A 5yf0A-5u38A:
undetectable		 5yf0A-5u38A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_B_TRPB403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 5u38 LECTIN
(Platypodium
elegans) 		4 / 7 GLU A 129
TRP A 141
ARG A 156
PRO A 143
 MN  A 302 (-2.7A)
None
None
None
 1.50A 6a4iB-5u38A:
undetectable		 6a4iB-5u38A:
19.17