SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u3k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_2
(TRANSTHYRETIN)		 5u3k DH511.2 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.71A 1ictD-5u3kL:
undetectable		 1ictD-5u3kL:
24.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OLD_B_IPHB2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 5u3k DH511.2 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 TYR L  36
HIS L  38
PRO L  44
TYR L  87
 None
 0.40A 2oldA-5u3kL:
16.2
2oldB-5u3kL:
20.3		 2oldA-5u3kL:
41.96
2oldB-5u3kL:
41.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 5u3k DH511.2 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 7 TYR L  36
HIS L  38
PRO L  44
TYR L  87
 None
 0.40A 2ombC-5u3kL:
18.2
2ombD-5u3kL:
20.0		 2ombC-5u3kL:
41.96
2ombD-5u3kL:
41.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 5u3k DH511.2 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 5 TYR L  36
GLN L  89
LEU L  96
PHE L  98
 None
 0.94A 3ls4L-5u3kL:
25.8		 3ls4L-5u3kL:
58.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 5u3k DH511.2 FAB LIGHT
CHAIN
(Homo
sapiens) 		3 / 3 ARG L 142
GLN L 166
GLU L 165
 None
 0.91A 4tvtA-5u3kL:
undetectable		 4tvtA-5u3kL:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)		 5u3k DH511.2 FAB LIGHT
CHAIN
(Homo
sapiens) 		4 / 8 THR L  74
SER L  63
THR L  72
SER L  65
 None
 0.97A 5l4eA-5u3kL:
undetectable
5l4eB-5u3kL:
undetectable
5l4eC-5u3kL:
undetectable
5l4eD-5u3kL:
3.2
5l4eE-5u3kL:
undetectable		 5l4eA-5u3kL:
20.97
5l4eB-5u3kL:
20.97
5l4eC-5u3kL:
20.97
5l4eD-5u3kL:
20.97
5l4eE-5u3kL:
20.97