SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u4h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CTR_A_TFPA153_1
(CALMODULIN)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 9 ILE A 206
LEU A 199
MET A 172
ALA A 174
VAL A 216
 None
 1.26A 1ctrA-5u4hA:
undetectable		 1ctrA-5u4hA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DDS_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A 390
ALA A 373
LEU A 339
ILE A 245
THR A 369
 None
 1.16A 1ddsB-5u4hA:
undetectable		 1ddsB-5u4hA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 11 LEU A  96
GLU A 168
LEU A 195
ILE A  39
LEU A  34
 None
 1.11A 1g50A-5u4hA:
undetectable		 1g50A-5u4hA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 MET A 307
LEU A 260
LEU A 283
VAL A 274
VAL A  16
 None
 1.01A 1hrkA-5u4hA:
undetectable		 1hrkA-5u4hA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		4 / 5 ILE A 118
ARG A 332
ASP A  49
ASN A  51
 0V5  A 509 (-4.5A)
FMT  A 507 (-3.5A)
None
None
 1.32A 1kiaD-5u4hA:
undetectable		 1kiaD-5u4hA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		4 / 4 ILE A 118
ARG A 332
ASP A  49
ASN A  51
 0V5  A 509 (-4.5A)
FMT  A 507 (-3.5A)
None
None
 1.31A 1nbiC-5u4hA:
undetectable		 1nbiC-5u4hA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		4 / 4 ILE A 118
ARG A 332
ASP A  49
ASN A  51
 0V5  A 509 (-4.5A)
FMT  A 507 (-3.5A)
None
None
 1.33A 1nbiD-5u4hA:
undetectable		 1nbiD-5u4hA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_2
(ANGIOTENSIN
CONVERTING ENZYME)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		4 / 4 SER A 238
VAL A  16
PHE A 267
VAL A 314
 None
 1.45A 1o86A-5u4hA:
undetectable		 1o86A-5u4hA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 10 ILE A 390
ALA A 373
LEU A 339
ILE A 245
THR A 369
 None
 1.14A 1rb3A-5u4hA:
undetectable		 1rb3A-5u4hA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RD7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A 234
ALA A  21
THR A 252
ILE A 281
LEU A 264
 None
 0.86A 1rd7B-5u4hA:
undetectable		 1rd7B-5u4hA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A 390
ALA A 373
LEU A 339
ILE A 245
THR A 369
 None
 1.06A 1re7A-5u4hA:
undetectable		 1re7A-5u4hA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A 170
ALA A 173
ALA A 146
LEU A  98
ILE A 137
 None
 1.02A 2h77A-5u4hA:
undetectable		 2h77A-5u4hA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H79_A_T3A1_1
(THRA PROTEIN)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A 170
ALA A 173
ALA A 146
LEU A  98
ILE A 137
 None
 1.00A 2h79A-5u4hA:
undetectable		 2h79A-5u4hA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA701_0
(FERROCHELATASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 MET A 307
LEU A 260
LEU A 283
VAL A 274
VAL A  16
 None
 1.04A 2hrcA-5u4hA:
undetectable		 2hrcA-5u4hA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1605_0
(FERROCHELATASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 MET A 307
LEU A 260
LEU A 283
VAL A 274
VAL A  16
 None
 1.05A 2hrcB-5u4hA:
undetectable		 2hrcB-5u4hA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 LEU A  96
GLU A 168
LEU A 195
ILE A  39
LEU A  34
 None
 1.09A 2j7xA-5u4hA:
undetectable		 2j7xA-5u4hA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		3 / 3 SER A 258
HIS A 254
ASP A  69
 None
 0.65A 2oxtA-5u4hA:
undetectable		 2oxtA-5u4hA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 11 MET A 307
LEU A 260
LEU A 283
VAL A 274
VAL A  16
 None
 1.22A 2po5B-5u4hA:
undetectable		 2po5B-5u4hA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 MET A 307
LEU A 260
LEU A 283
VAL A 274
VAL A  16
 None
 1.06A 2po7A-5u4hA:
undetectable		 2po7A-5u4hA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_2
(PROTEASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 10 LEU A 214
ALA A 174
VAL A 157
ALA A 186
ILE A 183
 None
 0.82A 3ekpB-5u4hA:
undetectable		 3ekpB-5u4hA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_1
(PROTEASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 10 LEU A 214
ALA A 174
VAL A 157
ALA A 186
ILE A 183
 None
 0.88A 3ekpC-5u4hA:
undetectable		 3ekpC-5u4hA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A 170
ALA A 173
ALA A 146
LEU A  98
ILE A 137
 None
 0.99A 3gwsX-5u4hA:
undetectable		 3gwsX-5u4hA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_A_LEIA16_0
(COIL SER L16D-PEN)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		4 / 6 LYS A 406
GLN A 408
LEU A 410
LEU A  12
 None
 0.88A 3h5gA-5u4hA:
undetectable
3h5gC-5u4hA:
undetectable		 3h5gA-5u4hA:
6.05
3h5gC-5u4hA:
6.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEG_A_BAXA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		4 / 6 MET A 342
VAL A 366
ILE A 390
LEU A 389
 None
 0.82A 3hegA-5u4hA:
undetectable		 3hegA-5u4hA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_B_AG2B1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 9 GLY A 237
SER A 238
TYR A 400
LEU A  47
ASP A 232
 None
 1.47A 3n2oA-5u4hA:
undetectable
3n2oB-5u4hA:
undetectable		 3n2oA-5u4hA:
24.96
3n2oB-5u4hA:
24.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		3 / 3 HIS A 254
ARG A  17
GLU A  15
 None
 0.86A 3qf1A-5u4hA:
undetectable		 3qf1A-5u4hA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL0_A_FOLA160_0
(DIHYDROFOLATE
REDUCTASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A 390
ALA A 373
LEU A 339
ILE A 245
THR A 369
 None
 1.13A 3ql0A-5u4hA:
undetectable		 3ql0A-5u4hA:
18.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V4T_A_ACTA502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		4 / 5 TYR A  85
VAL A  88
SER A 111
GLY A 114
 None
 0.38A 3v4tA-5u4hA:
64.4
3v4tD-5u4hA:
63.8		 3v4tA-5u4hA:
58.37
3v4tD-5u4hA:
58.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V4T_E_ACTE502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		3 / 3 LYS A  22
ARG A 332
LEU A 371
 FMT  A 507 ( 2.7A)
FMT  A 507 (-3.5A)
FMT  A 507 ( 4.9A)
 1.42A 3v4tE-5u4hA:
64.0		 3v4tE-5u4hA:
58.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		4 / 7 ALA A  93
ILE A  95
HIS A 126
GLY A 165
 None
 0.44A 3v4tH-5u4hA:
64.3		 3v4tH-5u4hA:
58.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1476_0
(MJ0495-LIKE PROTEIN)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		4 / 5 ILE A  39
ALA A  31
HIS A 223
MET A 202
 None
 1.22A 4ac9B-5u4hA:
undetectable
4ac9C-5u4hA:
undetectable		 4ac9B-5u4hA:
22.31
4ac9C-5u4hA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1476_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		4 / 5 ILE A  39
ALA A  31
HIS A 223
MET A 202
 None
 1.25A 4acaB-5u4hA:
undetectable
4acaC-5u4hA:
undetectable		 4acaB-5u4hA:
22.31
4acaC-5u4hA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 10 VAL A 366
ALA A 368
SER A 340
LEU A 361
THR A 369
 None
 1.50A 4eilB-5u4hA:
undetectable		 4eilB-5u4hA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_G_FOLG703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 10 VAL A 366
ALA A 368
SER A 340
LEU A 361
THR A 369
 None
 1.48A 4eilG-5u4hA:
undetectable		 4eilG-5u4hA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 LEU A  96
GLU A 168
LEU A 195
ILE A  39
LEU A  34
 None
 1.07A 4j24A-5u4hA:
undetectable		 4j24A-5u4hA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 LEU A  96
GLU A 168
LEU A 195
ILE A  39
LEU A  34
 None
 1.03A 4j24B-5u4hA:
undetectable		 4j24B-5u4hA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 LEU A  96
GLU A 168
LEU A 195
ILE A  39
LEU A  34
 None
 1.06A 4j24C-5u4hA:
undetectable		 4j24C-5u4hA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 LEU A  96
GLU A 168
ILE A  39
LEU A  41
LEU A  34
 None
 1.07A 4j24D-5u4hA:
undetectable		 4j24D-5u4hA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 LEU A  96
GLU A 168
LEU A 195
ILE A  39
LEU A  34
 None
 1.04A 4j26A-5u4hA:
undetectable		 4j26A-5u4hA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 LEU A  96
GLU A 168
LEU A 195
ILE A  39
LEU A  34
 None
 1.04A 4j26B-5u4hA:
undetectable		 4j26B-5u4hA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJL_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A 234
ALA A  21
THR A 252
ILE A 281
LEU A 264
 None
 1.02A 4kjlA-5u4hA:
undetectable		 4kjlA-5u4hA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_1
(MDR769 HIV-1
PROTEASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 11 GLY A 271
ALA A 272
ASP A 284
ILE A 245
VAL A 274
 None
 1.00A 4l1aA-5u4hA:
undetectable		 4l1aA-5u4hA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A 170
ALA A 173
ALA A 146
LEU A  98
ILE A 137
 None
 1.03A 4lnwA-5u4hA:
undetectable		 4lnwA-5u4hA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A 170
ALA A 173
ALA A 146
LEU A  98
ILE A 137
 None
 1.03A 4lnxA-5u4hA:
undetectable		 4lnxA-5u4hA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A 390
LEU A 407
PHE A 375
ARG A 372
ILE A 245
 None
None
None
FMT  A 507 (-3.7A)
None
 1.02A 4m6kA-5u4hA:
undetectable		 4m6kA-5u4hA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A 234
ALA A  21
LEU A 259
THR A 252
ILE A 281
 None
 1.11A 4ptjA-5u4hA:
undetectable		 4ptjA-5u4hA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 11 LEU A  96
GLU A 168
LEU A 195
ILE A  39
LEU A  34
 None
 1.12A 4pxmB-5u4hA:
undetectable		 4pxmB-5u4hA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLF_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 11 ILE A 390
ALA A 373
LEU A 339
ILE A 245
THR A 369
 None
 1.16A 4qlfA-5u4hA:
undetectable		 4qlfA-5u4hA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A 390
ALA A 373
LEU A 339
ILE A 245
THR A 369
 None
 1.11A 4qlgB-5u4hA:
undetectable		 4qlgB-5u4hA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 PHE A 267
ILE A 311
ALA A 244
THR A 252
LEU A 264
 None
 1.38A 4qzuA-5u4hA:
undetectable		 4qzuA-5u4hA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 9 THR A 388
ILE A 393
LEU A 361
ILE A 245
PHE A   4
 None
 1.28A 4r38C-5u4hA:
undetectable		 4r38C-5u4hA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 10 THR A 252
ILE A 234
LEU A 410
VAL A 378
LEU A 379
 None
 1.44A 4r3aB-5u4hA:
undetectable		 4r3aB-5u4hA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_A_15UA301_1
(THROMBIN HEAVY CHAIN)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  34
LEU A 133
ALA A 129
ALA A 174
GLY A  99
 None
 1.44A 4rn6A-5u4hA:
undetectable		 4rn6A-5u4hA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5F_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A 234
ALA A  21
LEU A 259
THR A 252
ILE A 281
 None
 1.14A 4x5fA-5u4hA:
undetectable		 4x5fA-5u4hA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5F_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A 234
ALA A  21
LEU A 259
THR A 252
ILE A 281
 None
 1.14A 4x5fB-5u4hA:
undetectable		 4x5fB-5u4hA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5G_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A 234
ALA A  21
LEU A 259
THR A 252
ILE A 281
 None
 1.14A 4x5gA-5u4hA:
undetectable		 4x5gA-5u4hA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 LEU A  96
GLU A 168
LEU A 195
ILE A  39
LEU A  34
 None
 1.13A 5gtrA-5u4hA:
undetectable		 5gtrA-5u4hA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 ALA A 316
GLY A 357
ALA A 380
LEU A 377
SER A 340
 None
 1.38A 5jglB-5u4hA:
undetectable		 5jglB-5u4hA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 11 ILE A  33
LEU A  98
ALA A 173
VAL A  62
LEU A  56
 None
 1.18A 5ji0A-5u4hA:
undetectable		 5ji0A-5u4hA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 LEU A 240
LEU A 379
VAL A  16
GLY A  14
LEU A  12
 None
 1.09A 5jw1B-5u4hA:
undetectable		 5jw1B-5u4hA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_1
(PROTEASE PR5-DRV)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 10 LEU A 382
ALA A 244
ILE A 311
GLY A 237
VAL A 378
 None
 0.98A 5kr1A-5u4hA:
undetectable		 5kr1A-5u4hA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		3 / 3 VAL A 358
LYS A 291
MET A 270
 None
 0.99A 5nknA-5u4hA:
undetectable		 5nknA-5u4hA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		6 / 12 LEU A  96
GLU A 168
LEU A 195
ILE A  39
LEU A  41
LEU A  34
 None
 1.19A 5toaB-5u4hA:
undetectable		 5toaB-5u4hA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		4 / 6 ALA A  93
PRO A 113
VAL A  88
ASP A  49
 None
 0.92A 5umd2-5u4hA:
undetectable
5umdF-5u4hA:
undetectable		 5umd2-5u4hA:
11.98
5umdF-5u4hA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_1
(CYTOCHROME P450 3A4)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 PHE A   4
ASP A 397
ALA A 243
THR A 246
ALA A 412
 None
 1.30A 5vcgA-5u4hA:
undetectable		 5vcgA-5u4hA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_2
(TUBULIN BETA CHAIN)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 LEU A 379
LEU A  12
ALA A 242
ILE A 414
ALA A 412
 None
 1.23A 5xiwD-5u4hA:
undetectable		 5xiwD-5u4hA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A 396
GLN A 310
ILE A 245
LEU A 382
ILE A 390
 None
 1.06A 5y2tB-5u4hA:
undetectable		 5y2tB-5u4hA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 ARG A  17
GLY A  20
LEU A  29
VAL A  71
LEU A 371
 None
None
None
None
FMT  A 507 ( 4.9A)
 0.89A 5ycnA-5u4hA:
undetectable		 5ycnA-5u4hA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 10 ILE A  33
ILE A 192
ALA A 196
LEU A 199
ALA A 204
 None
 1.33A 5zjiB-5u4hA:
undetectable		 5zjiB-5u4hA:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  96
GLU A 168
LEU A 195
ILE A  39
LEU A  34
 None
 1.11A 6cbzB-5u4hA:
undetectable		 6cbzB-5u4hA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A  39
THR A  70
VAL A  44
LEU A  78
TYR A 105
 None
 1.20A 6djzA-5u4hA:
undetectable		 6djzA-5u4hA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 LEU A 195
PHE A 159
VAL A 157
LEU A 222
ALA A 175
 None
 1.15A 6djzA-5u4hA:
undetectable		 6djzA-5u4hA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 12 LEU A 195
PHE A 159
VAL A 157
LEU A 222
ALA A 175
 None
 1.05A 6djzC-5u4hA:
undetectable		 6djzC-5u4hA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_B_TRPB502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE
(Acinetobacter
baumannii) 		5 / 10 TYR A 239
ALA A 242
LEU A 379
TYR A 400
VAL A 378
 None
 1.41A 6g2pB-5u4hA:
undetectable		 6g2pB-5u4hA:
22.58