SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u4q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 ALA A  62
ASP A  60
LEU A  59
LEU A   4
ILE A 109
 None
NAD  A 401 (-3.2A)
None
None
None
 1.07A 1ra3A-5u4qA:
undetectable		 1ra3A-5u4qA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RD7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 ALA A  62
ASP A  60
LEU A  59
LEU A   4
ILE A 109
 None
NAD  A 401 (-3.2A)
None
None
None
 1.02A 1rd7B-5u4qA:
undetectable		 1rd7B-5u4qA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A  66
ILE A 109
GLY A 112
VAL A  28
ILE A  30
 None
 0.85A 2hs1B-5u4qA:
undetectable		 2hs1B-5u4qA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.74A 2pxcA-5u4qA:
4.1		 2pxcA-5u4qA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		3 / 3 TYR A 182
VAL A 317
THR A 218
 None
 0.64A 2ygnA-5u4qA:
undetectable		 2ygnA-5u4qA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		3 / 3 TYR A 219
GLU A 225
ASP A 232
 None
 0.89A 3bxoB-5u4qA:
6.7		 3bxoB-5u4qA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_1
(HIV-1 PROTEASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A  66
ILE A 109
GLY A 112
VAL A  28
ILE A  30
 None
 0.92A 3d1zA-5u4qA:
undetectable		 3d1zA-5u4qA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.78A 3p97A-5u4qA:
5.8		 3p97A-5u4qA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.80A 3p97C-5u4qA:
5.0		 3p97C-5u4qA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQ9_A_MTXA2001_1
(DIHYDROFOLATE
REDUCTASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 ALA A  62
ASP A  60
LEU A  59
LEU A   4
ILE A 109
 None
NAD  A 401 (-3.2A)
None
None
None
 1.03A 3tq9A-5u4qA:
undetectable		 3tq9A-5u4qA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQB_A_FOLA2001_0
(DIHYDROFOLATE
REDUCTASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 11 ALA A  62
ASP A  60
LEU A  59
LEU A   4
ILE A 109
 None
NAD  A 401 (-3.2A)
None
None
None
 1.01A 3tqbA-5u4qA:
1.6		 3tqbA-5u4qA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.78A 4ctjA-5u4qA:
4.5		 4ctjA-5u4qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.82A 4ctjC-5u4qA:
5.9		 4ctjC-5u4qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.78A 4ctkA-5u4qA:
6.0		 4ctkA-5u4qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.80A 4ctkC-5u4qA:
5.9		 4ctkC-5u4qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFR_B_MTXB162_1
(DIHYDROFOLATE
REDUCTASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 ALA A  62
ASP A  60
LEU A  59
LEU A   4
ILE A 109
 None
NAD  A 401 (-3.2A)
None
None
None
 1.07A 4dfrB-5u4qA:
undetectable		 4dfrB-5u4qA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 ALA A 124
PHE A 178
ILE A 220
GLY A  13
VAL A 227
 NAD  A 401 (-3.3A)
NAD  A 401 (-4.7A)
None
None
None
 1.03A 4nkvC-5u4qA:
undetectable		 4nkvC-5u4qA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 ALA A 124
PHE A 178
ILE A 220
GLY A  13
VAL A 227
 NAD  A 401 (-3.3A)
NAD  A 401 (-4.7A)
None
None
None
 1.03A 4nkvD-5u4qA:
undetectable		 4nkvD-5u4qA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P66_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 11 ALA A  62
ASP A  60
LEU A  59
LEU A   4
ILE A 109
 None
NAD  A 401 (-3.2A)
None
None
None
 1.10A 4p66A-5u4qA:
undetectable		 4p66A-5u4qA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 LEU A 176
ILE A  80
ILE A 260
ALA A 226
ILE A  12
 None
None
None
None
NAD  A 401 (-3.9A)
 1.10A 4rp8C-5u4qA:
undetectable		 4rp8C-5u4qA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YBN_A_ACTA303_0
(FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		3 / 3 VAL A 321
TYR A 271
ALA A 274
 None
 0.52A 4ybnA-5u4qA:
undetectable		 4ybnA-5u4qA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.78A 5e9qA-5u4qA:
6.1		 5e9qA-5u4qA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.84A 5e9qC-5u4qA:
5.9		 5e9qC-5u4qA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.77A 5ec8A-5u4qA:
5.9		 5ec8A-5u4qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.79A 5ec8C-5u4qA:
4.5		 5ec8C-5u4qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.77A 5ehgA-5u4qA:
6.0		 5ehgA-5u4qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.80A 5ehgC-5u4qA:
5.2		 5ehgC-5u4qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.78A 5eifA-5u4qA:
4.9		 5eifA-5u4qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.82A 5eifC-5u4qA:
4.6		 5eifC-5u4qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.78A 5eiwC-5u4qA:
5.8		 5eiwC-5u4qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.77A 5ekxB-5u4qA:
5.5		 5ekxB-5u4qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 ILE A  16
VAL A 309
ILE A 260
LEU A 305
GLY A 310
 None
 1.05A 5ienA-5u4qA:
undetectable		 5ienA-5u4qA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		6 / 12 ILE A  80
LEU A 231
VAL A 309
ILE A 260
LEU A 305
GLY A 310
 None
 1.17A 5ienA-5u4qA:
undetectable		 5ienA-5u4qA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.84A 5ikmA-5u4qA:
4.9		 5ikmA-5u4qA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.79A 5kqrA-5u4qA:
6.1		 5kqrA-5u4qA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.79A 5kqsA-5u4qA:
3.4		 5kqsA-5u4qA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.79A 5m5bA-5u4qA:
5.9		 5m5bA-5u4qA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.79A 5njvA-5u4qA:
5.5		 5njvA-5u4qA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_B_SAMB301_0
(NS5)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.79A 5njvB-5u4qA:
5.8		 5njvB-5u4qA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_C_SAMC301_0
(NS5)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.85A 5njvC-5u4qA:
5.3		 5njvC-5u4qA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.79A 5vimA-5u4qA:
5.7		 5vimA-5u4qA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.77A 5vimB-5u4qA:
5.8		 5vimB-5u4qA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.83A 5wz1A-5u4qA:
6.1		 5wz1A-5u4qA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.84A 5wz1B-5u4qA:
5.9		 5wz1B-5u4qA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.84A 5wz1C-5u4qA:
5.9		 5wz1C-5u4qA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.85A 5wz1D-5u4qA:
6.0		 5wz1D-5u4qA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.84A 5wz1E-5u4qA:
6.0		 5wz1E-5u4qA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.85A 5wz1F-5u4qA:
6.0		 5wz1F-5u4qA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.85A 5wz1G-5u4qA:
5.9		 5wz1G-5u4qA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.85A 5wz1H-5u4qA:
6.1		 5wz1H-5u4qA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.78A 5wz2A-5u4qA:
5.2		 5wz2A-5u4qA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.79A 5wz2B-5u4qA:
6.3		 5wz2B-5u4qA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 183
GLY A  13
GLY A 186
VAL A   5
ILE A  16
 CL  A 402 (-4.3A)
None
CL  A 402 ( 4.4A)
None
None
 0.83A 5wz2C-5u4qA:
5.2		 5wz2C-5u4qA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 5u4q DTDP-GLUCOSE
4,6-DEHYDRATASE
(Klebsiella
pneumoniae) 		4 / 6 PHE A 311
LEU A 305
ALA A 226
GLN A 303
 None
 1.08A 6b89B-5u4qA:
1.9		 6b89B-5u4qA:
19.27