SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u4u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 5u4u MGC81300 PROTEIN
(Xenopus
laevis) 		3 / 3 ASN A 742
ALA A 730
ASN A 699
 None
 0.76A 1n4fA-5u4uA:
undetectable		 1n4fA-5u4uA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 5u4u MGC81300 PROTEIN
(Xenopus
laevis) 		5 / 11 ILE A 597
VAL A 596
CYH A 656
LEU A 693
ILE A 635
 None
 1.21A 1pkvA-5u4uA:
undetectable
1pkvB-5u4uA:
undetectable		 1pkvA-5u4uA:
16.85
1pkvB-5u4uA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODH_G_ACTG710_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 5u4u MGC81300 PROTEIN
(Xenopus
laevis) 		4 / 4 ARG A 751
ILE A 623
TYR A 621
ILE A 746
 None
 1.49A 5odhG-5u4uA:
undetectable		 5odhG-5u4uA:
13.64