SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u65'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_1
(HMG-COA REDUCTASE)		 5u65 VHH-5
(Camelus
dromedarius) 		4 / 8 ARG A  35
SER A  50
SER A  95
ASN A 100
 None
 1.18A 1hwkA-5u65A:
undetectable		 1hwkA-5u65A:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 5u65 VHH-5
(Camelus
dromedarius) 		4 / 8 ARG A  35
SER A  50
SER A  95
ASN A 100
 None
 1.16A 1hwkC-5u65A:
undetectable		 1hwkC-5u65A:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 5u65 VHH-5
(Camelus
dromedarius) 		4 / 8 ARG A  35
SER A  50
SER A  95
ASN A 100
 None
 1.16A 1hwkD-5u65A:
undetectable		 1hwkD-5u65A:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_A_ACTA601_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5u65 VHH-5
(Camelus
dromedarius) 		4 / 7 SER A  94
ALA A  93
SER A  95
THR A  96
 None
 0.89A 2i91A-5u65A:
undetectable		 2i91A-5u65A:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_B_ACTB602_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5u65 VHH-5
(Camelus
dromedarius) 		4 / 7 SER A  94
ALA A  93
SER A  95
THR A  96
 None
 0.89A 2i91B-5u65A:
undetectable		 2i91B-5u65A:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 5u65 VHH-5
(Camelus
dromedarius) 		4 / 4 THR A  28
VAL A  78
GLY A  55
THR A  56
 SO4  A 202 (-3.4A)
None
None
None
 0.66A 3cflA-5u65A:
undetectable		 3cflA-5u65A:
17.63