SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u6f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
4 / 8 THR A  20
GLY A 225
THR A 278
ILE A 269
None
0.80A 1c9sI-5u6fA:
undetectable
1c9sJ-5u6fA:
undetectable
1c9sI-5u6fA:
undetectable
1c9sJ-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 10 GLY A 225
ALA A 280
ILE A 269
GLY A  22
THR A  20
None
1.14A 1c9sN-5u6fA:
1.6
1c9sO-5u6fA:
2.2
1c9sN-5u6fA:
undetectable
1c9sO-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 10 GLY A 225
THR A 278
ILE A 269
GLY A  22
THR A  20
None
0.87A 1c9sN-5u6fA:
1.6
1c9sO-5u6fA:
2.2
1c9sN-5u6fA:
undetectable
1c9sO-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 11 GLY A 225
ALA A 280
ILE A 269
GLY A  22
THR A  20
None
1.13A 1c9sP-5u6fA:
1.6
1c9sQ-5u6fA:
1.6
1c9sP-5u6fA:
undetectable
1c9sQ-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 11 GLY A 225
THR A 278
ILE A 269
GLY A  22
THR A  20
None
0.86A 1c9sP-5u6fA:
1.6
1c9sQ-5u6fA:
1.6
1c9sP-5u6fA:
undetectable
1c9sQ-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 9 GLY A 225
ALA A 280
ILE A 269
GLY A  22
THR A  20
None
1.15A 1c9sQ-5u6fA:
1.6
1c9sR-5u6fA:
1.9
1c9sQ-5u6fA:
undetectable
1c9sR-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 9 GLY A 225
THR A 278
ILE A 269
GLY A  22
THR A  20
None
0.87A 1c9sQ-5u6fA:
1.6
1c9sR-5u6fA:
1.9
1c9sQ-5u6fA:
undetectable
1c9sR-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
4 / 8 GLY A 225
THR A 278
ILE A 269
THR A  20
None
0.81A 1c9sU-5u6fA:
undetectable
1c9sV-5u6fA:
undetectable
1c9sU-5u6fA:
undetectable
1c9sV-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 10 GLY A  22
THR A  20
GLY A 225
ALA A 280
ILE A 269
None
1.15A 1c9sL-5u6fA:
2.1
1c9sV-5u6fA:
1.9
1c9sL-5u6fA:
undetectable
1c9sV-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 10 GLY A  22
THR A  20
GLY A 225
THR A 278
ILE A 269
None
0.89A 1c9sL-5u6fA:
2.1
1c9sV-5u6fA:
1.9
1c9sL-5u6fA:
undetectable
1c9sV-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 9 GLY A  22
THR A  20
GLY A 225
ALA A 280
ILE A 269
None
1.18A 1gtfD-5u6fA:
1.9
1gtfE-5u6fA:
1.9
1gtfD-5u6fA:
undetectable
1gtfE-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 9 GLY A  22
THR A  20
GLY A 225
THR A 278
ILE A 269
None
0.90A 1gtfD-5u6fA:
1.9
1gtfE-5u6fA:
1.9
1gtfD-5u6fA:
undetectable
1gtfE-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 10 GLY A  22
THR A  20
GLY A 225
THR A 278
ILE A 269
None
0.93A 1gtfJ-5u6fA:
2.0
1gtfK-5u6fA:
1.9
1gtfJ-5u6fA:
undetectable
1gtfK-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 11 GLY A 225
THR A 278
ILE A 269
GLY A  22
THR A  20
None
0.88A 1gtfQ-5u6fA:
1.9
1gtfR-5u6fA:
1.9
1gtfQ-5u6fA:
undetectable
1gtfR-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 9 GLY A 225
ALA A 280
ILE A 269
GLY A  22
THR A  20
None
1.14A 1gtfR-5u6fA:
1.9
1gtfS-5u6fA:
1.5
1gtfR-5u6fA:
undetectable
1gtfS-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 9 GLY A 225
THR A 278
ILE A 269
GLY A  22
THR A  20
None
0.89A 1gtfR-5u6fA:
1.9
1gtfS-5u6fA:
1.5
1gtfR-5u6fA:
undetectable
1gtfS-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 11 GLY A 225
ALA A 280
ILE A 269
GLY A  22
THR A  20
None
1.15A 1gtfS-5u6fA:
1.5
1gtfT-5u6fA:
1.9
1gtfS-5u6fA:
undetectable
1gtfT-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 11 GLY A 225
THR A 278
ILE A 269
GLY A  22
THR A  20
None
0.88A 1gtfS-5u6fA:
1.5
1gtfT-5u6fA:
1.9
1gtfS-5u6fA:
undetectable
1gtfT-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
4 / 6 THR A  20
GLY A 225
THR A 278
ILE A 269
None
0.85A 1gtnD-5u6fA:
1.4
1gtnE-5u6fA:
1.9
1gtnD-5u6fA:
undetectable
1gtnE-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
4 / 7 THR A  20
GLY A 225
THR A 278
ILE A 269
None
0.84A 1gtnF-5u6fA:
1.6
1gtnG-5u6fA:
2.2
1gtnF-5u6fA:
undetectable
1gtnG-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
4 / 7 THR A  20
GLY A 225
THR A 278
ILE A 269
None
0.85A 1gtnJ-5u6fA:
1.9
1gtnK-5u6fA:
undetectable
1gtnJ-5u6fA:
undetectable
1gtnK-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 11 GLY A 225
ALA A 280
ILE A 269
GLY A  22
THR A  20
None
1.13A 1gtnT-5u6fA:
1.9
1gtnU-5u6fA:
1.9
1gtnT-5u6fA:
undetectable
1gtnU-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 11 GLY A 225
THR A 278
ILE A 269
GLY A  22
THR A  20
None
0.89A 1gtnT-5u6fA:
1.9
1gtnU-5u6fA:
1.9
1gtnT-5u6fA:
undetectable
1gtnU-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 12 GLY A  22
THR A  20
GLY A 225
THR A 278
ILE A 269
None
0.90A 1gtnL-5u6fA:
2.1
1gtnV-5u6fA:
1.8
1gtnL-5u6fA:
undetectable
1gtnV-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
4 / 7 TYR A  44
GLU A 133
SER A 146
VAL A 149
None
0.92A 1tv8B-5u6fA:
undetectable
1tv8B-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 10 GLY A 225
THR A 278
ILE A 269
GLY A  22
THR A  20
None
0.89A 1utdE-5u6fA:
1.9
1utdF-5u6fA:
1.9
1utdE-5u6fA:
undetectable
1utdF-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 10 GLY A 225
THR A 278
ILE A 269
GLY A  22
THR A  20
None
0.91A 1utdH-5u6fA:
2.3
1utdI-5u6fA:
1.6
1utdH-5u6fA:
undetectable
1utdI-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 12 GLY A 225
THR A 278
ILE A 269
GLY A  22
THR A  20
None
0.89A 1utdL-5u6fA:
2.2
1utdM-5u6fA:
1.9
1utdL-5u6fA:
undetectable
1utdM-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 12 GLY A 225
THR A 278
ILE A 269
GLY A  22
THR A  20
None
0.90A 1utdO-5u6fA:
1.5
1utdP-5u6fA:
1.9
1utdO-5u6fA:
undetectable
1utdP-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 11 GLY A 225
THR A 278
ILE A 269
GLY A  22
THR A  20
None
0.89A 1utdP-5u6fA:
1.9
1utdQ-5u6fA:
2.2
1utdP-5u6fA:
undetectable
1utdQ-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 11 GLY A 225
ALA A 280
ILE A 269
GLY A  22
THR A  20
None
1.14A 1utdS-5u6fA:
1.9
1utdT-5u6fA:
1.9
1utdS-5u6fA:
undetectable
1utdT-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 11 GLY A 225
THR A 278
ILE A 269
GLY A  22
THR A  20
None
0.87A 1utdS-5u6fA:
1.9
1utdT-5u6fA:
1.9
1utdS-5u6fA:
undetectable
1utdT-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 10 GLY A 225
ALA A 280
ILE A 269
GLY A  22
THR A  20
None
1.13A 1utdU-5u6fA:
1.9
1utdV-5u6fA:
1.9
1utdU-5u6fA:
undetectable
1utdV-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 10 GLY A 225
THR A 278
ILE A 269
GLY A  22
THR A  20
None
0.87A 1utdU-5u6fA:
1.9
1utdV-5u6fA:
1.9
1utdU-5u6fA:
undetectable
1utdV-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 11 GLY A  22
THR A  20
GLY A 225
THR A 278
ILE A 269
None
0.91A 1utdL-5u6fA:
2.2
1utdV-5u6fA:
1.9
1utdL-5u6fA:
undetectable
1utdV-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
4 / 7 LEU A 211
PHE A 209
ILE A 230
GLY A 214
None
0.84A 2v0mC-5u6fA:
undetectable
2v0mC-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
4 / 6 SER A 259
GLU A 264
VAL A 284
THR A 285
None
1.12A 4lnxA-5u6fA:
undetectable
4lnxA-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
3 / 3 GLU A 124
TRP A 127
ASN A 153
None
1.07A 5dv4A-5u6fA:
undetectable
5dv4A-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 10 GLY A  22
THR A  20
GLY A 225
THR A 278
ILE A 269
None
0.92A 5eevA-5u6fA:
1.9
5eevB-5u6fA:
1.9
5eevA-5u6fA:
undetectable
5eevB-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 10 GLY A  22
THR A  20
GLY A 225
THR A 278
ILE A 269
None
0.92A 5eewA-5u6fA:
1.9
5eewB-5u6fA:
1.9
5eewA-5u6fA:
undetectable
5eewB-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 10 GLY A  22
THR A  20
GLY A 225
THR A 278
ILE A 269
None
0.92A 5eexA-5u6fA:
1.9
5eexB-5u6fA:
undetectable
5eexA-5u6fA:
undetectable
5eexB-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 10 GLY A  22
THR A  20
GLY A 225
THR A 278
ILE A 269
None
0.92A 5eeyA-5u6fA:
1.9
5eeyB-5u6fA:
1.9
5eeyA-5u6fA:
undetectable
5eeyB-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 10 GLY A  22
THR A  20
GLY A 225
THR A 278
ILE A 269
None
0.92A 5eezA-5u6fA:
1.8
5eezB-5u6fA:
undetectable
5eezA-5u6fA:
undetectable
5eezB-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 10 GLY A  22
THR A  20
GLY A 225
THR A 278
ILE A 269
None
0.92A 5ef0A-5u6fA:
1.9
5ef0B-5u6fA:
1.9
5ef0A-5u6fA:
undetectable
5ef0B-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 10 GLY A  22
THR A  20
GLY A 225
THR A 278
ILE A 269
None
0.92A 5ef1A-5u6fA:
1.8
5ef1B-5u6fA:
1.9
5ef1A-5u6fA:
undetectable
5ef1B-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 10 GLY A  22
THR A  20
GLY A 225
THR A 278
ILE A 269
None
0.92A 5ef2A-5u6fA:
1.9
5ef2B-5u6fA:
1.9
5ef2A-5u6fA:
undetectable
5ef2B-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 10 GLY A  22
THR A  20
GLY A 225
THR A 278
ILE A 269
None
0.92A 5ef3A-5u6fA:
1.9
5ef3B-5u6fA:
1.9
5ef3A-5u6fA:
undetectable
5ef3B-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 12 GLU A 216
LEU A 171
LYS A 172
ALA A 265
VAL A 255
None
1.24A 5kbwB-5u6fA:
undetectable
5kbwB-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
5 / 10 VAL A  11
ILE A  29
LEU A  50
ALA A  16
PHE A  17
None
1.06A 5mxbA-5u6fA:
undetectable
5mxbA-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
4 / 6 SER A 161
ASP A 117
GLN A  53
GLU A 165
None
1.50A 6djzA-5u6fA:
undetectable
6djzA-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris)
4 / 6 ASP A 245
GLN A 235
VAL A 238
ALA A 265
None
1.11A 6djzB-5u6fA:
undetectable
6djzB-5u6fA:
undetectable