SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u7s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_A_NIOA704_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5u7s FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE
(Acinetobacter
baumannii) 		4 / 4 SER A 107
PHE A 181
GLU A 142
GLY A 141
 None
 1.36A 1icvA-5u7sA:
undetectable
1icvB-5u7sA:
undetectable		 1icvA-5u7sA:
21.17
1icvB-5u7sA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 5u7s FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE
(Acinetobacter
baumannii) 		4 / 6 ASP A 111
GLY A 109
THR A 114
PRO A 115
 None
 0.89A 1n4fA-5u7sA:
undetectable		 1n4fA-5u7sA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 5u7s FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE
(Acinetobacter
baumannii) 		4 / 6 ASP A 111
GLY A 112
THR A 114
PRO A 115
 None
 0.77A 1n4fA-5u7sA:
undetectable		 1n4fA-5u7sA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 5u7s FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE
(Acinetobacter
baumannii) 		5 / 8 LEU A  10
ASN A 275
GLU A 140
HIS A 232
ALA A 189
 None
CIT  A 401 (-4.5A)
None
NA  A 402 ( 3.4A)
None
 1.02A 2bnnA-5u7sA:
undetectable
2bnnB-5u7sA:
undetectable		 2bnnA-5u7sA:
21.53
2bnnB-5u7sA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_B_0LIB2_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5u7s FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE
(Acinetobacter
baumannii) 		6 / 12 ALA A  22
ILE A 192
LEU A 229
VAL A 230
LEU A  10
ALA A 189
 None
 1.32A 3ik3B-5u7sA:
undetectable		 3ik3B-5u7sA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5u7s FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE
(Acinetobacter
baumannii) 		4 / 6 VAL A 139
VAL A 341
ILE A  95
ARG A 126
 None
 1.11A 3ms9A-5u7sA:
undetectable		 3ms9A-5u7sA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5u7s FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE
(Acinetobacter
baumannii) 		4 / 6 VAL A 139
VAL A 341
ILE A  95
ARG A 126
 None
 1.10A 3mssA-5u7sA:
undetectable		 3mssA-5u7sA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5u7s FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE
(Acinetobacter
baumannii) 		4 / 6 VAL A 139
VAL A 341
ILE A  95
ARG A 126
 None
 1.11A 3mssC-5u7sA:
undetectable		 3mssC-5u7sA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 5u7s FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE
(Acinetobacter
baumannii) 		5 / 12 ARG A 205
PHE A 203
GLY A 257
ALA A 213
GLY A 209
 None
 1.33A 3v3oB-5u7sA:
undetectable		 3v3oB-5u7sA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 5u7s FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE
(Acinetobacter
baumannii) 		5 / 11 ARG A 205
PHE A 203
GLY A 257
ALA A 213
GLY A 209
 None
 1.26A 4a6nA-5u7sA:
undetectable		 4a6nA-5u7sA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5u7s FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE
(Acinetobacter
baumannii) 		4 / 8 VAL A 128
CYH A 135
VAL A 139
ILE A  95
 None
 1.11A 4aftD-5u7sA:
undetectable
4aftE-5u7sA:
undetectable		 4aftD-5u7sA:
18.26
4aftE-5u7sA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_1
(CYTOCHROME P450 2D6)		 5u7s FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE
(Acinetobacter
baumannii) 		5 / 12 LEU A 229
GLY A 195
LEU A 212
SER A 234
VAL A 258
 None
 0.97A 4wnwB-5u7sA:
undetectable		 4wnwB-5u7sA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 5u7s FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE
(Acinetobacter
baumannii) 		5 / 10 GLY A 109
GLY A 106
SER A 107
LEU A 108
GLU A 142
 None
 1.24A 5hwkA-5u7sA:
undetectable		 5hwkA-5u7sA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 5u7s FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE
(Acinetobacter
baumannii) 		5 / 10 GLY A 109
GLY A 106
SER A 107
LEU A 108
GLU A 142
 None
 1.24A 5hwkB-5u7sA:
undetectable		 5hwkB-5u7sA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 5u7s FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE
(Acinetobacter
baumannii) 		5 / 11 ILE A 276
ILE A 315
VAL A 230
MET A 231
LEU A 263
 None
 1.44A 5jkwA-5u7sA:
undetectable		 5jkwA-5u7sA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5u7s FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE
(Acinetobacter
baumannii) 		5 / 12 ARG A 343
ILE A 335
ILE A  70
ILE A 332
HIS A   0
 None
 1.11A 5y2tB-5u7sA:
undetectable		 5y2tB-5u7sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 5u7s FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE
(Acinetobacter
baumannii) 		5 / 12 ILE A 192
PHE A 181
GLY A 141
ASP A 105
LEU A 146
 None
 1.07A 6dwnD-5u7sA:
undetectable		 6dwnD-5u7sA:
12.28