SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u8e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 5u8e ARGININE KINASE
(Polybetes
pythagoricus) 		5 / 9 TYR A  75
THR A 269
LEU A 275
VAL A  65
ILE A  67
 None
 1.38A 1gebA-5u8eA:
undetectable		 1gebA-5u8eA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 5u8e ARGININE KINASE
(Polybetes
pythagoricus) 		5 / 12 ILE A  86
TYR A  89
ILE A 279
ALA A 338
ASN A 327
 None
 1.08A 1jtxA-5u8eA:
undetectable		 1jtxA-5u8eA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH8_A_VIBA1_1
(MAJOR PRION PROTEIN)		 5u8e ARGININE KINASE
(Polybetes
pythagoricus) 		4 / 6 HIS A  99
ASP A 263
ASP A 262
TYR A  75
 None
 1.43A 2lh8A-5u8eA:
undetectable		 2lh8A-5u8eA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 5u8e ARGININE KINASE
(Polybetes
pythagoricus) 		5 / 12 ILE A 350
ILE A 346
LEU A 287
VAL A 283
VAL A 308
 None
 1.06A 2nnhA-5u8eA:
undetectable		 2nnhA-5u8eA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5u8e ARGININE KINASE
(Polybetes
pythagoricus) 		3 / 3 ASN A 274
ARG A 330
ASP A 324
 None
 0.98A 2qe6A-5u8eA:
undetectable		 2qe6A-5u8eA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5u8e ARGININE KINASE
(Polybetes
pythagoricus) 		3 / 3 ASN A 274
ARG A 330
ASP A 324
 None
 0.98A 2qe6B-5u8eA:
undetectable		 2qe6B-5u8eA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_B_X2NB1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 5u8e ARGININE KINASE
(Polybetes
pythagoricus) 		5 / 12 PRO A 138
ALA A 200
ALA A  45
THR A  76
LEU A 268
 None
 1.24A 2x2nB-5u8eA:
undetectable		 2x2nB-5u8eA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_0
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5u8e ARGININE KINASE
(Polybetes
pythagoricus) 		5 / 12 SER A 122
MET A 342
ILE A 346
LEU A 219
GLU A 162
 None
 1.50A 3aocC-5u8eA:
1.3		 3aocC-5u8eA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 5u8e ARGININE KINASE
(Polybetes
pythagoricus) 		4 / 5 ILE A  86
HIS A  90
TYR A  75
GLY A 276
 None
 1.17A 3b9mA-5u8eA:
1.0		 3b9mA-5u8eA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5u8e ARGININE KINASE
(Polybetes
pythagoricus) 		3 / 3 ASN A 223
MET A 173
PHE A 188
 None
 1.13A 3g4lD-5u8eA:
undetectable		 3g4lD-5u8eA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 5u8e ARGININE KINASE
(Polybetes
pythagoricus) 		5 / 12 GLY A 133
PHE A 259
LEU A 131
GLU A  73
ALA A  72
 None
 1.17A 3kkzA-5u8eA:
undetectable		 3kkzA-5u8eA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_1
(SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5u8e ARGININE KINASE
(Polybetes
pythagoricus) 		4 / 6 LEU A 275
SER A 260
PHE A 259
GLU A 254
 None
 1.30A 5b8iA-5u8eA:
undetectable		 5b8iA-5u8eA:
25.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_A_PFLA412_1
(PROTON-GATED ION
CHANNEL)		 5u8e ARGININE KINASE
(Polybetes
pythagoricus) 		5 / 10 ILE A 346
ILE A 325
MET A 342
VAL A 113
THR A 123
 None
 1.33A 5mzrA-5u8eA:
undetectable		 5mzrA-5u8eA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 5u8e ARGININE KINASE
(Polybetes
pythagoricus) 		4 / 5 ASP A 174
PRO A 205
GLU A 149
THR A 171
 None
 1.30A 5uxcA-5u8eA:
0.2		 5uxcA-5u8eA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)		 5u8e ARGININE KINASE
(Polybetes
pythagoricus) 		5 / 12 VAL A 250
PHE A 104
THR A 277
GLY A 276
GLY A 266
 None
 0.93A 6brdB-5u8eA:
1.0		 6brdB-5u8eA:
11.46