SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u9c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1872_0
(FPRA)		 5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE
(Yersinia
enterocolitica) 		4 / 5 SER A 130
ASN A  80
ALA A  62
GLU A  63
 None
 1.43A 1lqtA-5u9cA:
undetectable
1lqtB-5u9cA:
undetectable		 1lqtA-5u9cA:
22.39
1lqtB-5u9cA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1429_0
(FPRA)		 5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE
(Yersinia
enterocolitica) 		4 / 5 SER A 130
ASN A  80
ALA A  62
GLU A  63
 None
 1.42A 1lquA-5u9cA:
3.4
1lquB-5u9cA:
3.2		 1lquA-5u9cA:
22.39
1lquB-5u9cA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE
(Yersinia
enterocolitica) 		5 / 11 GLY A 157
GLY A 158
TYR A 283
PHE A 287
HIS A 163
 None
 0.98A 1w76A-5u9cA:
3.1		 1w76A-5u9cA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE
(Yersinia
enterocolitica) 		4 / 6 GLY A  95
PRO A  54
LYS A  53
THR A  50
 None
 1.37A 2m2oB-5u9cA:
undetectable		 2m2oB-5u9cA:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_1
(ESTROGEN RECEPTOR)		 5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE
(Yersinia
enterocolitica) 		4 / 6 ALA A 251
ASP A  67
GLU A  70
ARG A 129
 None
 1.22A 2ouzA-5u9cA:
undetectable		 2ouzA-5u9cA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE
(Yersinia
enterocolitica) 		4 / 7 ILE A 229
GLY A 230
PHE A 235
ILE A 180
 None
 0.79A 2y7wC-5u9cA:
undetectable		 2y7wC-5u9cA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE
(Yersinia
enterocolitica) 		3 / 3 ASP A  67
ARG A  71
ARG A 186
 None
 0.92A 3k37A-5u9cA:
undetectable		 3k37A-5u9cA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE
(Yersinia
enterocolitica) 		4 / 5 GLY A  10
THR A  19
ILE A  30
VAL A  29
 None
 0.85A 3wriA-5u9cA:
undetectable		 3wriA-5u9cA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE
(Yersinia
enterocolitica) 		4 / 5 GLY A  10
THR A  19
ILE A  30
VAL A  29
 None
 0.84A 3wriB-5u9cA:
undetectable		 3wriB-5u9cA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE
(Yersinia
enterocolitica) 		6 / 12 MET A 154
ALA A  61
PHE A  60
ILE A 149
LEU A  99
ILE A 200
 None
 1.11A 4kjjA-5u9cA:
undetectable		 4kjjA-5u9cA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJK_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE
(Yersinia
enterocolitica) 		5 / 12 MET A 154
PHE A  60
ILE A 149
LEU A  99
ILE A 200
 None
 1.09A 4kjkA-5u9cA:
undetectable		 4kjkA-5u9cA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX6_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE
(Yersinia
enterocolitica) 		5 / 12 MET A 154
PHE A  60
ILE A 149
LEU A  99
ILE A 200
 None
 1.12A 4nx6A-5u9cA:
undetectable		 4nx6A-5u9cA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSS_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE
(Yersinia
enterocolitica) 		6 / 12 MET A 154
ALA A  61
PHE A  60
ILE A 149
LEU A  99
ILE A 200
 None
 1.11A 4pssA-5u9cA:
undetectable		 4pssA-5u9cA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSY_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE
(Yersinia
enterocolitica) 		5 / 12 MET A 154
ALA A  61
PHE A  60
ILE A 149
LEU A  99
 None
 0.98A 4psyA-5u9cA:
undetectable		 4psyA-5u9cA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE
(Yersinia
enterocolitica) 		4 / 7 VAL A  18
ILE A 149
ALA A 203
ILE A 148
 None
 0.66A 4uxqA-5u9cA:
undetectable		 4uxqA-5u9cA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)		 5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE
(Yersinia
enterocolitica) 		3 / 3 PRO A 254
ARG A 186
GLU A 257
 None
 0.93A 5j6hA-5u9cA:
undetectable		 5j6hA-5u9cA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE
(Yersinia
enterocolitica) 		5 / 12 PHE A  60
LEU A 147
LEU A 196
PHE A 199
ILE A 204
 None
 1.16A 5ljcA-5u9cA:
undetectable		 5ljcA-5u9cA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE
(Yersinia
enterocolitica) 		4 / 5 ALA A  88
SER A 137
GLY A 134
TYR A 100
 None
 1.06A 5yodB-5u9cA:
undetectable		 5yodB-5u9cA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE
(Yersinia
enterocolitica) 		4 / 5 ALA A  88
SER A 137
GLY A 134
TYR A 100
 None
 1.01A 5yodD-5u9cA:
undetectable		 5yodD-5u9cA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE
(Yersinia
enterocolitica) 		5 / 10 SER A 137
GLY A 134
ILE A  45
ALA A  83
LEU A  82
 None
 1.37A 5zjiA-5u9cA:
undetectable
5zjiJ-5u9cA:
undetectable		 5zjiA-5u9cA:
17.18
5zjiJ-5u9cA:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE
(Yersinia
enterocolitica) 		3 / 3 ARG A 186
PHE A 223
PHE A 247
 None
None
BDF  A 301 ( 3.7A)
 1.03A 6nknC-5u9cA:
undetectable
6nknJ-5u9cA:
undetectable		 6nknC-5u9cA:
19.59
6nknJ-5u9cA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE
(Yersinia
enterocolitica) 		5 / 12 MET A 154
PHE A  60
ILE A 149
LEU A  99
ILE A 200
 None
 1.06A 7dfrA-5u9cA:
undetectable		 7dfrA-5u9cA:
19.66