SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u9l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 5u9l PARALOG OF
ACCUMULATION AND
REPLICATION OF
CHLOROPLASTS 6
(PARC6)
(Arabidopsis
thaliana) 		4 / 5 ILE A 769
LEU A 696
ASP A 689
ALA A 755
 None
 1.02A 2opxA-5u9lA:
undetectable		 2opxA-5u9lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5u9l PARALOG OF
ACCUMULATION AND
REPLICATION OF
CHLOROPLASTS 6
(PARC6)
(Arabidopsis
thaliana) 		4 / 8 LEU A 708
LEU A 721
VAL A 643
GLY A 644
 None
 0.68A 2po5A-5u9lA:
undetectable		 2po5A-5u9lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 5u9l PARALOG OF
ACCUMULATION AND
REPLICATION OF
CHLOROPLASTS 6
(PARC6)
(Arabidopsis
thaliana) 		4 / 6 ALA A 788
ASN A 787
LEU A 779
VAL A 780
 None
 1.01A 4g24A-5u9lA:
undetectable		 4g24A-5u9lA:
9.94