SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u9m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 5u9m SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		5 / 12 GLY B 213
ILE B 192
LEU B  84
ASP B 208
THR B 146
 None
 1.16A 1jg2A-5u9mB:
undetectable		 1jg2A-5u9mB:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 5u9m SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		5 / 11 GLY B 213
ILE B 192
LEU B  84
ASP B 208
THR B 146
 None
 1.11A 1jg3B-5u9mB:
undetectable		 1jg3B-5u9mB:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 5u9m SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		5 / 11 ASN B  30
GLY B  33
THR B  56
ILE B  57
LEU B  28
 None
 1.35A 3bexC-5u9mB:
undetectable
3bexD-5u9mB:
undetectable		 3bexC-5u9mB:
22.86
3bexD-5u9mB:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 5u9m SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		5 / 10 LEU B  28
ASN B  30
GLY B  33
THR B  56
ILE B  57
 None
 1.35A 3bexC-5u9mB:
undetectable
3bexD-5u9mB:
undetectable		 3bexC-5u9mB:
22.86
3bexD-5u9mB:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 5u9m SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		5 / 10 ASN B  30
GLY B  33
THR B  56
ILE B  57
LEU B  28
 None
 1.34A 3bexE-5u9mB:
undetectable
3bexF-5u9mB:
undetectable		 3bexE-5u9mB:
22.86
3bexF-5u9mB:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 5u9m SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		5 / 11 LEU B  28
ASN B  30
GLY B  33
THR B  56
ILE B  57
 None
 1.34A 3bexE-5u9mB:
undetectable
3bexF-5u9mB:
undetectable		 3bexE-5u9mB:
22.86
3bexF-5u9mB:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 5u9m SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		5 / 11 ASN B  30
GLY B  33
THR B  56
ILE B  57
LEU B  28
 None
 1.40A 3bf1A-5u9mB:
undetectable
3bf1B-5u9mB:
undetectable		 3bf1A-5u9mB:
22.86
3bf1B-5u9mB:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 5u9m SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		5 / 11 ASN B  30
GLY B  33
THR B  56
ILE B  57
LEU B  28
 None
 1.36A 3bf1C-5u9mB:
undetectable
3bf1D-5u9mB:
undetectable		 3bf1C-5u9mB:
22.86
3bf1D-5u9mB:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 5u9m SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		5 / 11 LEU B  28
ASN B  30
GLY B  33
THR B  56
ILE B  57
 None
 1.34A 3bf1C-5u9mB:
undetectable
3bf1D-5u9mB:
undetectable		 3bf1C-5u9mB:
22.86
3bf1D-5u9mB:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 5u9m SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		5 / 11 ASN B  30
GLY B  33
THR B  56
ILE B  57
LEU B  28
 None
 1.32A 3bf1E-5u9mB:
undetectable
3bf1F-5u9mB:
undetectable		 3bf1E-5u9mB:
22.86
3bf1F-5u9mB:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 5u9m SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		5 / 11 LEU B  28
ASN B  30
GLY B  33
THR B  56
ILE B  57
 None
 1.35A 3bf1E-5u9mB:
undetectable
3bf1F-5u9mB:
undetectable		 3bf1E-5u9mB:
22.86
3bf1F-5u9mB:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 5u9m SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		5 / 12 ASN B  30
GLY B  33
THR B  56
ILE B  57
LEU B  28
 None
 1.30A 5b8hA-5u9mB:
undetectable
5b8hB-5u9mB:
undetectable		 5b8hA-5u9mB:
20.58
5b8hB-5u9mB:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 5u9m SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		5 / 12 LEU B  28
ASN B  30
GLY B  33
THR B  56
ILE B  57
 None
 1.28A 5b8hA-5u9mB:
undetectable
5b8hB-5u9mB:
undetectable		 5b8hA-5u9mB:
20.58
5b8hB-5u9mB:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 5u9m SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE
(Saccharomyces
cerevisiae) 		4 / 5 PHE B 116
PHE B 175
LEU B 115
LEU B 103
 None
 0.87A 5veuH-5u9mB:
undetectable		 5veuH-5u9mB:
18.96