SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u9o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_A_CAMA502_0
(CYTOCHROME P450-CAM)		 5u9o PLASTID DIVISION
PROTEIN CDP1,
CHLOROPLASTIC,PLASTI
D DIVISION PROTEIN
PDV1
(Arabidopsis
thaliana) 		4 / 5 PHE A 810
TYR A 798
LEU A 773
VAL A 703
 None
 1.50A 1dz6A-5u9oA:
undetectable		 1dz6A-5u9oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NOS_B_H4BB1011_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 5u9o PLASTID DIVISION
PROTEIN CDP1,
CHLOROPLASTIC,PLASTI
D DIVISION PROTEIN
PDV1
(Arabidopsis
thaliana) 		4 / 6 PHE A 745
GLU A 706
VAL A 703
TRP A 700
 None
 1.35A 3nosA-5u9oA:
undetectable
3nosB-5u9oA:
undetectable		 3nosA-5u9oA:
11.43
3nosB-5u9oA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5u9o PLASTID DIVISION
PROTEIN CDP1,
CHLOROPLASTIC,PLASTI
D DIVISION PROTEIN
PDV1
(Arabidopsis
thaliana) 		4 / 6 VAL A 703
TRP A 700
PHE A 745
GLU A 706
 None
 1.38A 4d39A-5u9oA:
undetectable
4d39B-5u9oA:
undetectable		 4d39A-5u9oA:
11.32
4d39B-5u9oA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 5u9o PLASTID DIVISION
PROTEIN CDP1,
CHLOROPLASTIC,PLASTI
D DIVISION PROTEIN
PDV1
(Arabidopsis
thaliana) 		5 / 7 ARG A 855
GLY A 856
ALA A 777
GLU A 775
GLN A 728
 None
 1.30A 4g0uB-5u9oA:
undetectable		 4g0uB-5u9oA:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)		 5u9o PLASTID DIVISION
PROTEIN CDP1,
CHLOROPLASTIC,PLASTI
D DIVISION PROTEIN
PDV1
(Arabidopsis
thaliana) 		4 / 6 GLY A 856
ALA A 777
GLU A 775
GLN A 728
 None
 1.06A 4g0uA-5u9oA:
undetectable		 4g0uA-5u9oA:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCP_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5u9o PLASTID DIVISION
PROTEIN CDP1,
CHLOROPLASTIC,PLASTI
D DIVISION PROTEIN
PDV1
(Arabidopsis
thaliana) 		4 / 6 VAL A 703
TRP A 700
PHE A 745
GLU A 706
 None
 1.42A 4kcpA-5u9oA:
undetectable
4kcpB-5u9oA:
undetectable		 4kcpA-5u9oA:
11.32
4kcpB-5u9oA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCR_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5u9o PLASTID DIVISION
PROTEIN CDP1,
CHLOROPLASTIC,PLASTI
D DIVISION PROTEIN
PDV1
(Arabidopsis
thaliana) 		4 / 6 VAL A 703
TRP A 700
PHE A 745
GLU A 706
 None
 1.40A 4kcrA-5u9oA:
undetectable
4kcrB-5u9oA:
undetectable		 4kcrA-5u9oA:
11.32
4kcrB-5u9oA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCS_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5u9o PLASTID DIVISION
PROTEIN CDP1,
CHLOROPLASTIC,PLASTI
D DIVISION PROTEIN
PDV1
(Arabidopsis
thaliana) 		4 / 6 VAL A 703
TRP A 700
PHE A 745
GLU A 706
 None
 1.39A 4kcsA-5u9oA:
undetectable
4kcsB-5u9oA:
undetectable		 4kcsA-5u9oA:
11.32
4kcsB-5u9oA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 5u9o PLASTID DIVISION
PROTEIN CDP1,
CHLOROPLASTIC,PLASTI
D DIVISION PROTEIN
PDV1
(Arabidopsis
thaliana) 		5 / 12 GLY A 709
TYR A 790
LEU A 732
GLU A 775
PHE A 745
 None
 1.03A 4pd9A-5u9oA:
undetectable		 4pd9A-5u9oA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5u9o PLASTID DIVISION
PROTEIN CDP1,
CHLOROPLASTIC,PLASTI
D DIVISION PROTEIN
PDV1
(Arabidopsis
thaliana) 		4 / 5 GLU A 775
GLU A 701
TYR A 798
TYR A 794
 None
 1.26A 4twdA-5u9oA:
undetectable
4twdE-5u9oA:
undetectable		 4twdA-5u9oA:
13.36
4twdE-5u9oA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_B_377B401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5u9o PLASTID DIVISION
PROTEIN CDP1,
CHLOROPLASTIC,PLASTI
D DIVISION PROTEIN
PDV1
(Arabidopsis
thaliana) 		4 / 5 TYR A 794
GLU A 775
GLU A 701
TYR A 798
 None
 1.21A 4twdA-5u9oA:
undetectable
4twdB-5u9oA:
undetectable		 4twdA-5u9oA:
13.36
4twdB-5u9oA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5u9o PLASTID DIVISION
PROTEIN CDP1,
CHLOROPLASTIC,PLASTI
D DIVISION PROTEIN
PDV1
(Arabidopsis
thaliana) 		4 / 7 GLU A 775
GLU A 701
TYR A 798
TYR A 794
 None
 1.22A 4twdF-5u9oA:
undetectable
4twdJ-5u9oA:
undetectable		 4twdF-5u9oA:
13.36
4twdJ-5u9oA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_H_377H401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5u9o PLASTID DIVISION
PROTEIN CDP1,
CHLOROPLASTIC,PLASTI
D DIVISION PROTEIN
PDV1
(Arabidopsis
thaliana) 		4 / 6 TYR A 794
GLU A 775
GLU A 701
TYR A 798
 None
 1.20A 4twdG-5u9oA:
undetectable
4twdH-5u9oA:
undetectable		 4twdG-5u9oA:
13.36
4twdH-5u9oA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_H_377H402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5u9o PLASTID DIVISION
PROTEIN CDP1,
CHLOROPLASTIC,PLASTI
D DIVISION PROTEIN
PDV1
(Arabidopsis
thaliana) 		4 / 5 TYR A 794
GLU A 775
GLU A 701
TYR A 798
 None
 1.21A 4twdH-5u9oA:
undetectable
4twdI-5u9oA:
undetectable		 4twdH-5u9oA:
13.36
4twdI-5u9oA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_2_BEZ2801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 5u9o PLASTID DIVISION
PROTEIN CDP1,
CHLOROPLASTIC,PLASTI
D DIVISION PROTEIN
PDV1
(Arabidopsis
thaliana) 		4 / 4 LEU A 772
ARG A 855
ILE A 796
ILE A 815
 None
 1.33A 5dzk2-5u9oA:
undetectable
5dzkM-5u9oA:
undetectable
5dzkN-5u9oA:
undetectable		 5dzk2-5u9oA:
undetectable
5dzkM-5u9oA:
undetectable
5dzkN-5u9oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV6_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5u9o PLASTID DIVISION
PROTEIN CDP1,
CHLOROPLASTIC,PLASTI
D DIVISION PROTEIN
PDV1
(Arabidopsis
thaliana) 		4 / 6 VAL A 703
TRP A 700
PHE A 745
GLU A 706
 None
 1.39A 5vv6A-5u9oA:
undetectable
5vv6B-5u9oA:
undetectable		 5vv6A-5u9oA:
11.32
5vv6B-5u9oA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV8_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5u9o PLASTID DIVISION
PROTEIN CDP1,
CHLOROPLASTIC,PLASTI
D DIVISION PROTEIN
PDV1
(Arabidopsis
thaliana) 		4 / 6 VAL A 703
TRP A 700
PHE A 745
GLU A 706
 None
 1.36A 5vv8A-5u9oA:
undetectable
5vv8B-5u9oA:
undetectable		 5vv8A-5u9oA:
11.32
5vv8B-5u9oA:
11.32