SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5u9p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5u9p GLUCONATE
5-DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ILE A  39
GLY A  21
GLY A  19
LEU A  52
LEU A  26
 None
NAP  A 301 ( 4.2A)
NAP  A 301 (-3.7A)
None
None
 1.08A 1rjdA-5u9pA:
5.9		 1rjdA-5u9pA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5u9p GLUCONATE
5-DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ILE A  39
GLY A  21
GLY A  19
LEU A  52
LEU A  26
 None
NAP  A 301 ( 4.2A)
NAP  A 301 (-3.7A)
None
None
 1.06A 1rjdB-5u9pA:
5.8		 1rjdB-5u9pA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5u9p GLUCONATE
5-DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ILE A  39
GLY A  21
GLY A  19
LEU A  52
LEU A  26
 None
NAP  A 301 ( 4.2A)
NAP  A 301 (-3.7A)
None
None
 1.07A 1rjdC-5u9pA:
5.6		 1rjdC-5u9pA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 5u9p GLUCONATE
5-DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 7 GLY A  31
ALA A 231
VAL A  94
ILE A  39
 None
 0.74A 3a2qA-5u9pA:
undetectable		 3a2qA-5u9pA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5u9p GLUCONATE
5-DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 GLY A  19
GLY A  21
ASP A  69
VAL A  70
VAL A 119
 NAP  A 301 (-3.7A)
NAP  A 301 ( 4.2A)
NAP  A 301 (-3.5A)
NAP  A 301 (-3.8A)
NAP  A 301 (-4.3A)
 0.88A 3dmfA-5u9pA:
6.7		 3dmfA-5u9pA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 5u9p GLUCONATE
5-DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 8 ILE A  41
ALA A  29
LEU A  16
ALA A  37
 None
 0.95A 3hrdA-5u9pA:
undetectable
3hrdB-5u9pA:
undetectable		 3hrdA-5u9pA:
21.96
3hrdB-5u9pA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5u9p GLUCONATE
5-DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 8 GLU A  46
LYS A  48
ASN A  45
ILE A  41
 None
NAP  A 301 ( 4.9A)
None
None
 1.09A 3kp6A-5u9pA:
undetectable
3kp6B-5u9pA:
undetectable		 3kp6A-5u9pA:
19.41
3kp6B-5u9pA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 5u9p GLUCONATE
5-DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 11 GLY A  19
ALA A  97
ILE A  17
ALA A  29
ASP A  43
 NAP  A 301 (-3.7A)
NAP  A 301 (-3.6A)
None
None
NAP  A 301 ( 4.2A)
 1.15A 3nmuB-5u9pA:
undetectable
3nmuJ-5u9pA:
7.7		 3nmuB-5u9pA:
22.51
3nmuJ-5u9pA:
25.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 5u9p GLUCONATE
5-DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 5 SER A 148
ILE A  24
TYR A 161
GLY A 192
 TLA  A 302 (-2.9A)
NAP  A 301 (-3.9A)
TLA  A 302 ( 4.0A)
None
 0.90A 3uboB-5u9pA:
5.7		 3uboB-5u9pA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)		 5u9p GLUCONATE
5-DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 5 PHE A 194
GLY A 252
THR A 254
VAL A 149
 None
 1.01A 3wrkD-5u9pA:
undetectable		 3wrkD-5u9pA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_A_ADNA401_1
(APH(2'')-ID)		 5u9p GLUCONATE
5-DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 10 ALA A  15
ILE A  17
ILE A 146
LEU A 189
ILE A 144
 None
None
NAP  A 301 (-4.4A)
None
None
 1.30A 4dtaA-5u9pA:
undetectable		 4dtaA-5u9pA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_A_MOAA502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 5u9p GLUCONATE
5-DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 8 ASP A 122
ASN A 126
THR A  18
GLY A  98
 EDO  A 304 ( 4.1A)
EDO  A 304 (-2.9A)
None
NAP  A 301 (-3.8A)
 0.93A 4fo4A-5u9pA:
undetectable		 4fo4A-5u9pA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5u9p GLUCONATE
5-DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 TYR A 161
GLY A  98
ILE A  24
GLY A  23
ASN A 199
 TLA  A 302 ( 4.0A)
NAP  A 301 (-3.8A)
NAP  A 301 (-3.9A)
NAP  A 301 (-3.5A)
TLA  A 302 ( 3.0A)
 1.17A 4obwA-5u9pA:
7.2		 4obwA-5u9pA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5u9p GLUCONATE
5-DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 TYR A 161
GLY A  98
ILE A  24
GLY A  23
ASN A 199
 TLA  A 302 ( 4.0A)
NAP  A 301 (-3.8A)
NAP  A 301 (-3.9A)
NAP  A 301 (-3.5A)
TLA  A 302 ( 3.0A)
 1.15A 4obwD-5u9pA:
6.4		 4obwD-5u9pA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5u9p GLUCONATE
5-DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 9 ILE A 144
ASN A  96
LEU A 198
VAL A 224
LEU A 227
 None
NAP  A 301 (-3.3A)
NAP  A 301 ( 3.5A)
None
None
 1.11A 4r38C-5u9pA:
undetectable		 4r38C-5u9pA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5u9p GLUCONATE
5-DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 10 ILE A 144
ASN A  96
LEU A 198
VAL A 224
LEU A 227
 None
NAP  A 301 (-3.3A)
NAP  A 301 ( 3.5A)
None
None
 1.30A 4r3aB-5u9pA:
undetectable		 4r3aB-5u9pA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5u9p GLUCONATE
5-DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 ILE A  39
ALA A  15
GLY A  60
GLY A  36
LEU A  10
 None
 0.90A 5i73A-5u9pA:
undetectable		 5i73A-5u9pA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUI_B_CTCB405_0
(TETRACYCLINE
DESTRUCTASE TET(50))		 5u9p GLUCONATE
5-DEHYDROGENASE
(Burkholderia
cenocepacia) 		5 / 12 GLY A  25
VAL A 168
GLY A 188
GLY A  98
VAL A  70
 None
None
None
NAP  A 301 (-3.8A)
NAP  A 301 (-3.8A)
 0.84A 5tuiB-5u9pA:
4.5		 5tuiB-5u9pA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 5u9p GLUCONATE
5-DEHYDROGENASE
(Burkholderia
cenocepacia) 		4 / 7 LEU A  28
VAL A 249
LEU A 189
LEU A 234
 None
 0.69A 6g9bA-5u9pA:
undetectable
6g9bB-5u9pA:
undetectable		 6g9bA-5u9pA:
16.33
6g9bB-5u9pA:
16.96