SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ua0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 5ua0 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 LEU A  92
VAL A 113
TYR A 110
GLY A 114
 None
 0.82A 1lweA-5ua0A:
undetectable		 1lweA-5ua0A:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 5ua0 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 LEU A  92
VAL A 113
TYR A 110
GLY A 114
 None
 0.98A 1s1xA-5ua0A:
undetectable		 1s1xA-5ua0A:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 5ua0 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 PHE A  53
ASN A  27
ARG A  78
VAL A 115
 None
 0.98A 1wu8A-5ua0A:
1.4
1wu8C-5ua0A:
undetectable		 1wu8A-5ua0A:
15.35
1wu8C-5ua0A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 5ua0 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 PHE A  53
ASN A  27
TYR A 110
VAL A 115
 None
 1.25A 1wu8A-5ua0A:
1.4
1wu8C-5ua0A:
undetectable		 1wu8A-5ua0A:
15.35
1wu8C-5ua0A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 5ua0 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 GLU A 158
VAL A 193
CYH A 196
 None
 0.93A 3fbxA-5ua0A:
undetectable		 3fbxA-5ua0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GVU_A_STIA1001_2
(TYROSINE-PROTEIN
KINASE ABL2)		 5ua0 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 VAL A  49
ILE A  38
TYR A 260
MET A 146
 None
 1.38A 3gvuA-5ua0A:
undetectable		 3gvuA-5ua0A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5ua0 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 GLY A  28
THR A  98
ASN A  27
 None
 0.60A 3v4tD-5ua0A:
undetectable		 3v4tD-5ua0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 5ua0 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 11 HIS A 252
HIS A 235
VAL A 175
LEU A 173
THR A 189
 None
 1.14A 4lu3A-5ua0A:
undetectable		 4lu3A-5ua0A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 5ua0 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 THR A  98
THR A 121
ASP A  96
TYR A 110
 None
 1.21A 4oltA-5ua0A:
undetectable		 4oltA-5ua0A:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 5ua0 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 THR A  98
THR A 121
ASP A  96
TYR A 110
 None
 1.23A 4oltB-5ua0A:
undetectable		 4oltB-5ua0A:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)		 5ua0 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE 2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 THR A  98
THR A 121
ASP A  96
TYR A 110
 None
 1.22A 4qwpA-5ua0A:
undetectable		 4qwpA-5ua0A:
13.89