SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ua2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 5ua2 HTH-TYPE
TRANSCRIPTIONAL
REPRESSOR KSTR
(Mycobacterium
tuberculosis) 		4 / 6 LEU A  43
THR A  46
PHE A  78
LEU A  74
 None
 1.12A 2wm3A-5ua2A:
undetectable		 2wm3A-5ua2A:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDZ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5ua2 HTH-TYPE
TRANSCRIPTIONAL
REPRESSOR KSTR
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 161
ILE A 181
GLY A 119
MET A 125
 None
 0.90A 4zdzA-5ua2A:
1.9		 4zdzA-5ua2A:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5ua2 HTH-TYPE
TRANSCRIPTIONAL
REPRESSOR KSTR
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  85
PHE A 161
ILE A 181
GLY A 119
MET A 125
 None
 1.20A 5eshA-5ua2A:
2.4		 5eshA-5ua2A:
10.42