SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uai'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 5uai METHIONYL-TRNA
FORMYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 246
LEU A 241
THR A 262
VAL A 273
ALA A 308
 None
 1.12A 1n5xA-5uaiA:
undetectable		 1n5xA-5uaiA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 5uai METHIONYL-TRNA
FORMYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 246
LEU A 241
THR A 262
VAL A 273
ALA A 308
 None
 1.12A 1n5xB-5uaiA:
undetectable		 1n5xB-5uaiA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5uai METHIONYL-TRNA
FORMYLTRANSFERASE
(Pseudomonas
aeruginosa) 		6 / 12 LEU A 172
LEU A 175
ALA A 179
GLU A 182
LEU A 153
LEU A 114
 None
 1.33A 1s9pA-5uaiA:
undetectable		 1s9pA-5uaiA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5uai METHIONYL-TRNA
FORMYLTRANSFERASE
(Pseudomonas
aeruginosa) 		6 / 12 LEU A 172
LEU A 175
ALA A 179
GLU A 182
LEU A 153
LEU A 114
 None
 1.35A 1s9pD-5uaiA:
undetectable		 1s9pD-5uaiA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 5uai METHIONYL-TRNA
FORMYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 5 LEU A 280
LEU A 282
LEU A 312
LEU A 215
 None
 1.05A 2ab2B-5uaiA:
undetectable		 2ab2B-5uaiA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 5uai METHIONYL-TRNA
FORMYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 10 GLU A  14
GLY A 176
VAL A 155
LEU A 168
THR A 157
 None
 1.27A 3a3yA-5uaiA:
undetectable		 3a3yA-5uaiA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_B_KKKB413_1
(FLAVOHEMOGLOBIN)		 5uai METHIONYL-TRNA
FORMYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  22
LEU A  24
LEU A  61
GLY A 176
PRO A 177
 None
 1.08A 3ozwB-5uaiA:
4.3		 3ozwB-5uaiA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RD0_A_EDPA175_1
(FERRITIN LIGHT CHAIN)		 5uai METHIONYL-TRNA
FORMYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 282
ALA A 266
ARG A 281
LEU A 285
 None
 1.15A 3rd0A-5uaiA:
undetectable		 3rd0A-5uaiA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 5uai METHIONYL-TRNA
FORMYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 6 PHE A 306
ALA A 244
PRO A 245
LEU A 287
 None
 0.92A 4dtzB-5uaiA:
undetectable		 4dtzB-5uaiA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 5uai METHIONYL-TRNA
FORMYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 7 PHE A 306
ALA A 244
PRO A 245
LEU A 287
 None
 0.90A 4du2A-5uaiA:
undetectable		 4du2A-5uaiA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 5uai METHIONYL-TRNA
FORMYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 7 PHE A 306
ALA A 244
PRO A 245
LEU A 287
 None
 0.86A 4du2B-5uaiA:
undetectable		 4du2B-5uaiA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 5uai METHIONYL-TRNA
FORMYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 10 PRO A 245
LEU A 241
ALA A 266
PHE A 295
PRO A 288
 None
 1.37A 5m0oA-5uaiA:
undetectable		 5m0oA-5uaiA:
21.57