SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ub6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5ub6 PHOSPHATE-BINDING
PROTEIN
(Xanthomonas
citri) 		3 / 3 GLN A 148
ILE A 134
HIS A 143
 POP  A 401 ( 4.5A)
None
None
 0.71A 1fm9A-5ub6A:
undetectable		 1fm9A-5ub6A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5ub6 PHOSPHATE-BINDING
PROTEIN
(Xanthomonas
citri) 		3 / 3 GLN A 148
ILE A 134
HIS A 143
 POP  A 401 ( 4.5A)
None
None
 0.73A 1k74A-5ub6A:
undetectable		 1k74A-5ub6A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 5ub6 PHOSPHATE-BINDING
PROTEIN
(Xanthomonas
citri) 		5 / 12 LYS A 226
PHE A 127
LEU A 125
PHE A 199
ASN A 195
 None
 1.32A 1nw3A-5ub6A:
undetectable		 1nw3A-5ub6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRH_A_NIOA200_1
(PROTEIN HP0721)		 5ub6 PHOSPHATE-BINDING
PROTEIN
(Xanthomonas
citri) 		4 / 7 GLY A 300
THR A 153
GLN A 104
LEU A 297
 None
POP  A 401 (-4.2A)
None
None
 1.03A 2xrhA-5ub6A:
undetectable		 2xrhA-5ub6A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 5ub6 PHOSPHATE-BINDING
PROTEIN
(Xanthomonas
citri) 		3 / 3 MET A 189
CYH A 170
PRO A 159
 None
 1.03A 3h52C-5ub6A:
undetectable		 3h52C-5ub6A:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_A_FUNA201_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 5ub6 PHOSPHATE-BINDING
PROTEIN
(Xanthomonas
citri) 		5 / 11 SER A 136
ILE A 134
VAL A 128
VAL A 207
ILE A 231
 None
 1.27A 3rf4A-5ub6A:
undetectable
3rf4C-5ub6A:
2.1		 3rf4A-5ub6A:
25.22
3rf4C-5ub6A:
25.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_B_FUNB202_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 5ub6 PHOSPHATE-BINDING
PROTEIN
(Xanthomonas
citri) 		5 / 11 ILE A 231
SER A 136
ILE A 134
VAL A 128
VAL A 207
 None
 1.31A 3rf4A-5ub6A:
undetectable
3rf4B-5ub6A:
undetectable		 3rf4A-5ub6A:
25.22
3rf4B-5ub6A:
25.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_C_FUNC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 5ub6 PHOSPHATE-BINDING
PROTEIN
(Xanthomonas
citri) 		5 / 11 ILE A 231
SER A 136
ILE A 134
VAL A 128
VAL A 207
 None
 1.30A 3rf4B-5ub6A:
undetectable
3rf4C-5ub6A:
2.1		 3rf4B-5ub6A:
25.22
3rf4C-5ub6A:
25.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5ub6 PHOSPHATE-BINDING
PROTEIN
(Xanthomonas
citri) 		5 / 12 GLN A 104
VAL A 304
ILE A  39
GLY A  97
ALA A 150
 None
 0.81A 3sufB-5ub6A:
undetectable		 3sufB-5ub6A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BKJ_B_STIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 5ub6 PHOSPHATE-BINDING
PROTEIN
(Xanthomonas
citri) 		4 / 5 LEU A 111
TYR A  83
MET A  80
ARG A  60
 None
 1.48A 4bkjB-5ub6A:
undetectable		 4bkjB-5ub6A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5ub6 PHOSPHATE-BINDING
PROTEIN
(Xanthomonas
citri) 		4 / 6 LEU A  54
VAL A  57
VAL A 253
ASP A  90
 None
 1.11A 4l4cA-5ub6A:
undetectable		 4l4cA-5ub6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 5ub6 PHOSPHATE-BINDING
PROTEIN
(Xanthomonas
citri) 		3 / 3 PRO A 159
MET A 160
TYR A 156
 None
 0.90A 4qa0B-5ub6A:
undetectable		 4qa0B-5ub6A:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 5ub6 PHOSPHATE-BINDING
PROTEIN
(Xanthomonas
citri) 		3 / 3 PRO A 159
MET A 160
TYR A 156
 None
 0.86A 4qa0A-5ub6A:
undetectable		 4qa0A-5ub6A:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 5ub6 PHOSPHATE-BINDING
PROTEIN
(Xanthomonas
citri) 		3 / 3 PRO A 159
MET A 160
TYR A 156
 None
 0.89A 4qa2B-5ub6A:
undetectable		 4qa2B-5ub6A:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 5ub6 PHOSPHATE-BINDING
PROTEIN
(Xanthomonas
citri) 		4 / 6 ARG A 293
ARG A 120
VAL A 238
ASP A 121
 None
 1.27A 4xqeA-5ub6A:
undetectable		 4xqeA-5ub6A:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 5ub6 PHOSPHATE-BINDING
PROTEIN
(Xanthomonas
citri) 		4 / 6 ARG A 293
ARG A 120
VAL A 238
ASP A 121
 None
 1.23A 4xqeB-5ub6A:
undetectable		 4xqeB-5ub6A:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5ub6 PHOSPHATE-BINDING
PROTEIN
(Xanthomonas
citri) 		3 / 3 TYR A 187
ALA A 150
TYR A 156
 None
 0.86A 5uunB-5ub6A:
undetectable		 5uunB-5ub6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YK2_A_ERYA501_0
(PROBABLE CONSERVED
ATP-BINDING PROTEIN
ABC TRANSPORTER)		 5ub6 PHOSPHATE-BINDING
PROTEIN
(Xanthomonas
citri) 		5 / 11 ARG A 240
ALA A  98
ILE A  39
ARG A  38
VAL A  92
 None
 1.10A 5yk2A-5ub6A:
undetectable		 5yk2A-5ub6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 5ub6 PHOSPHATE-BINDING
PROTEIN
(Xanthomonas
citri) 		3 / 3 TYR A  47
LEU A  54
ASP A  90
 None
 0.89A 5zv2B-5ub6A:
undetectable		 5zv2B-5ub6A:
20.83