SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5uba'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 5uba RNA PSEUDOURIDYLATE
SYNTHASE
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		4 / 5 TYR A 185
LEU A 152
VAL A 159
VAL A 181
 None
 1.17A 1t88B-5ubaA:
undetectable		 1t88B-5ubaA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_2
(VITAMIN D RECEPTOR)		 5uba RNA PSEUDOURIDYLATE
SYNTHASE
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		4 / 7 LEU A 275
LEU A 271
ILE A 264
ARG A 179
 None
CL  A 401 (-4.2A)
None
None
 1.23A 2hc4A-5ubaA:
undetectable		 2hc4A-5ubaA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5uba RNA PSEUDOURIDYLATE
SYNTHASE
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		4 / 5 TYR A 185
LEU A 152
VAL A 159
VAL A 181
 None
 1.19A 2m56A-5ubaA:
undetectable		 2m56A-5ubaA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5uba RNA PSEUDOURIDYLATE
SYNTHASE
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		4 / 6 TYR A 185
LEU A 152
VAL A 159
VAL A 181
 None
 1.19A 2zawA-5ubaA:
undetectable		 2zawA-5ubaA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5uba RNA PSEUDOURIDYLATE
SYNTHASE
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		4 / 5 TYR A 185
LEU A 152
VAL A 159
VAL A 181
 None
 1.22A 4l49A-5ubaA:
undetectable		 4l49A-5ubaA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5uba RNA PSEUDOURIDYLATE
SYNTHASE
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		5 / 10 LEU A 356
LEU A 308
LEU A 305
ILE A 188
HIS A 287
 None
 1.39A 4mk4A-5ubaA:
undetectable		 4mk4A-5ubaA:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5uba RNA PSEUDOURIDYLATE
SYNTHASE
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		5 / 10 ASP A 129
VAL A 130
LEU A  95
THR A  96
ALA A  94
 None
 1.22A 4yhaB-5ubaA:
undetectable		 4yhaB-5ubaA:
19.73