SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ubc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_A_BHSA1610_1
(NITRIC OXIDE
SYNTHASE)		 5ubc PROTEIN TOC75-3,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 SER A 246
ALA A 322
PHE A 243
GLU A 223
 None
 0.95A 1dmiA-5ubcA:
undetectable
1dmiB-5ubcA:
undetectable		 1dmiA-5ubcA:
19.56
1dmiB-5ubcA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 5ubc PROTEIN TOC75-3,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 THR A 231
PRO A 233
THR A 236
 None
 0.78A 209dC-5ubcA:
undetectable		 209dC-5ubcA:
4.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5ubc PROTEIN TOC75-3,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ASP A 432
LEU A 261
GLY A 364
GLN A 345
ILE A 439
 None
 1.14A 2ogyA-5ubcA:
undetectable		 2ogyA-5ubcA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5ubc PROTEIN TOC75-3,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 GLN A 400
ASP A 365
ILE A 366
VAL A 441
PHE A 404
 None
 1.09A 4dx5B-5ubcA:
undetectable		 4dx5B-5ubcA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 5ubc PROTEIN TOC75-3,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 GLY A 409
ILE A 366
ASN A 428
VAL A 441
LEU A 369
 None
 0.92A 4fr0A-5ubcA:
undetectable		 4fr0A-5ubcA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5ubc PROTEIN TOC75-3,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 GLN A 400
ASP A 365
ILE A 366
VAL A 441
PHE A 404
 None
 1.13A 4u8vB-5ubcA:
undetectable		 4u8vB-5ubcA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 5ubc PROTEIN TOC75-3,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 THR A 215
THR A 218
PHE A 349
 None
 0.61A 5cxvA-5ubcA:
undetectable		 5cxvA-5ubcA:
19.73